MYCN protein partners identified in NB cells. by Zhihui Liu (95891)

“…We demonstrate that MYCN cooperates with WDR5 and G9a to orchestrate global gene transcription. The targeting of both these cofactors is a novel therapeutic strategy to indirectly target the oncogenic activity of <i>MYCN</i>.…”

Effect of apixaban on platelet and fibrin interactions with damaged vessels exposed to flowing blood. by Gines Escolar (310448)

“…The size of platelet aggregates was apparently decreased in samples exposed to apixaban. (<b>C</b>) Activated and non activated prothrombin complex concentrates, aPCCs and PCCs, restored levels of fibrin deposited on the subendothelium. …”

Altered vesicular cargo composition in enriched fractions of <i>Rabgef1-KO</i> retina. by Passley Hargrove-Grimes (9915365)

“…<p>(A) Summary of proteins identified from mass spectrometric analysis of vesicle enriched sub-cellular fractions from control and <i>Rabgef1</i>^<i>-/-</i> retina. …”

Video_4_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Video_3_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Image_1_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.tif by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Video_1_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Image_2_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.tif by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

ODE modeling of WNT5A-EGF/AR signaling and experimental validation. by Zhiwei Ji (493628)

“…<p>(<b>A)</b> The effect of WNT5A on 22RV1 cell viability. …”

Video_2_Defective Neutrophil Transendothelial Migration and Lateral Motility in ARPC1B Deficiency Under Flow Conditions.mp4 by Lanette Kempers (10899027)

“…Here we show that under physiological flow conditions human ARPC1B-deficient neutrophils were able to transmigrate through TNF-α-pre-activated endothelial cells with a decreased efficiency and, once transmigrated, showed definite impairment in subendothelial crawling. …”

Data_Sheet_1_Methylseleninic Acid Sensitizes Ovarian Cancer Cells to T-Cell Mediated Killing by Decreasing PDL1 and VEGF Levels.docx by Deepika Nair (5625854)

“…Treatment of the ovarian cancer cell line A2780 with selenite and MSA increases NK cell mediated lysis, and enhances the cytolytic activity of T cells. …”

ART-naive and short-term ART experienced individuals have decreased frequency of CD161-expressing gut homing CD8+ T-cells. by Olivia Briceño (3369029)

Increased acetylated ATG proteins and decreased ATG5-ATG12 conjugation in the livers of L-<i>G6pc</i>-/- mice. by Jun-Ho Cho (4053676)

RIP3 depletion reduced the necrotic cells in the lung and decreased the expression of MLKL, but had no impact on cleaved caspase-3 in LPS-induced ARDS. by Linlin Wang (289071)

The decreased <i>in vivo</i> phagocytic activity of resKCs for acetylated LDL in LXRα KO and LXRα/β KO mice. by Takuya Ishikiriyama (6735674)

DataSheet1_Satellite observations reveal decreasing soil erosion in Northeast Inner Mongolia, China, over the past four decades.docx by Wei Jiang (14986)

“…Multisource satellite remote sensing with auxiliary data, including meteorology, land use, vegetation coverage, and digital elevation, was collected to establish a distributed soil erosion model to quantify the soil erosion intensity in Northeast Inner Mongolia. …”

Figure S1 from Membranous NECTIN-4 Expression Frequently Decreases during Metastatic Spread of Urothelial Carcinoma and Is Associated with Enfortumab Vedotin Resistance by Niklas Klümper (15048887)

Immune pathways in <i>Ae</i>. <i>aegypti</i> mosquitoes infected by DENV. by Ju-Mei Wang (6589220)

“…<p><b>A</b>, Heatmap of transcriptional variation in expression of immune-related genes (ROS pathways and AMP genes) in DENV-infected mosquitoes. …”

Data_Sheet_1_The HDAC6 Inhibitor Trichostatin A Acetylates Microtubules and Protects Axons From Excitotoxin-Induced Degeneration in a Compartmented Culture Model.PDF by Kelsey Hanson (5147819)

“…While there were no changes to tyrosinated tubulin or MAP1B, acetylated tubulin was significantly (p < 0.05) decreased by 40% at 6 h post-treatment. To determine whether increasing microtubule acetylation prior to kainic acid exposure could prevent axon fragmentation, we investigated the effect of reducing microtubule deacetylation with the HDAC6 inhibitor, trichostatin A. …”

Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression by Sathidpak Nantasanti (3181224)

“…We show that loss of Rb and p53 resulted in reduced Cyp3a expression decreased accumulation of protoporphyrin and consequently less ductular reaction in livers of mice fed with DDC for 3 weeks. …”