Sensitivity analysis of system behavior as a function of geochemical variation provides physiological context for <i>in situ</i> measurements. by Kristopher A. Hunt (5797163)

“…<p>Three scenarios (middle panel) predicted the metabolic space feasible for autotroph-heterotroph interactions of the entire community (top panel). Scenario A analyzes a community composed solely of an Fe(II) oxidizing autotroph (represented by R1 or Fe) and autotroph-consuming heterotroph (R4 or AC), which are present at relative population abundances of 0.3 and 0.5 autotroph to heterotroph. …”

Image_1_Effect of nutrient reductions on dissolved oxygen and pH: a case study of Narragansett bay.pdf by Hongjie Wang (54357)

“…We observed significant decreases in surface DO levels, concurrent with a significant increase in bottom DO, associated with the nitrogen load reduction. …”

image1_A Novel Antioxidant Protects Against Contrast Medium-Induced Acute Kidney Injury in Rats.tif by Shuo Huang (624671)

“…The results demonstrated that the CI-AKI rats caused a significant decrease in renal function accompanied by a remarkable increase in Malondialdehyde (MDA), bax, caspase-3, cytochrome c (Cyt C) level, TdT-mediated dUTP nick end labeling (TUNEL) positive apoptotic cells, and damaged mitochondria, while a decline in antioxidase activities and mitochondrial superoxide dismutase 2 (SOD2) expression compared with the control rats. …”

Data_Sheet_1_Evolution of benzodiazepine receptor agonist prescriptions in general practice: A registry-based study.docx by Kristien Coteur (12972584)

“…Among 65+ female patients, a decrease was found since 2006, with an annual percentage change of −0.7 (95% CI: −1.3, −0.1). …”

Table_5_Trichohyalin gene expression is negatively correlated with the severity of dermatitis in a canine atopic dermatitis model.XLSX by Rosanna Marsella (8606172)

“…Introduction<p>Canine atopic dermatitis (AD) closely mimics human AD and is recognized as a beneficial animal model. House dust mites (HDM) are a common allergen for both species. …”

Image_3_An INF-STAT Axis Augments Tissue Damage and Inflammation in a Mouse Model of Crohn's Disease.TIFF by Iris Stolzer (10829022)

“…However, a decrease in inflammatory cell death was still associated with mild inflammation in the small intestine. …”

Presentation_1_Immunization against nucleus pulposus antigens to accelerate degenerative disc disease in a rabbit model.PPTX by Andres F. Bonilla (14004456)

“…Imaging evaluation evidenced a decrease in disc height index and higher scores of disc degeneration in animals after disc punctures and in those animals that received the NP vaccine in addition to disc puncture. …”

Whole-Core 3D Multiphysics Transient Modeling of a Prismatic Micro High-Temperature Gas-Cooled Reactor by Marc C. Van Den Berg (21609902)

“…We furthermore contend that the graphite thermal conductivity values used in modeling should always be made explicit and that the temperature of irradiation should be included as a parameter since it can cause a sharp decrease (up to 97%) in the conductivity. …”

Table_2_The Effects of Psychological Interventions on Symptoms and Psychology of Functional Dyspepsia: A Systematic Review and Meta-Analysis.DOC by Zhongcao Wei (12372928)

“…</p>Results<p>Fourteen RCTs with a total of 1,434 FD patients were included. Compared with the control group, psychological interventions were significantly more likely to symptom improvement [RR = 1.74, 95% CI (1.12, 2.72), p = 0.01], relieve gastrointestinal symptoms scores at follow up [SMD = −1.06, 95% CI (−1.55, −0.57), p < 0.0001], relieve gastrointestinal symptoms scores at end of treatment [SMD = −0.98, 95% CI (−1.29, −0.67), p < 0.001], decrease anxiety [SMD = −0.8, 95% CI (−1.38, −0.22), p = 0.006] and depression levels [SMD = −1.11, 95% CI (−1.62, −0.61), p < 0.001]. …”

Effect of Anti-Obesity Drug on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Yu-Hao Zhou (156711)

“…</p> <h3>Conclusion/Significance</h3><p>We identified that anti-obesity therapy was associated with a decrease of weight regardless of the type of the drug. …”

Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein by Denys A. Khaperskyy (596268)

“…At the same time, loss of PA-X resulted in changes in the synthesis of select viral mRNAs and a decrease in viral protein accumulation. Collectively, these results significantly advance our understanding of IAV host shutoff, and suggest that the PA-X causes selective degradation of host mRNAs by discriminating some aspect of Pol II-dependent RNA biogenesis in the nucleus.…”

The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice by Jian Zheng (287758)

“…<div><p>A novel avian influenza virus H7N9 infection occurred among human populations since 2013. …”

Transcriptome analysis reveals a stress response of <i>Shewanella oneidensis</i> deprived of background levels of ionizing radiation by Hugo Castillo (5227337)

“…The greatest change observed in the treatment was the downregulation of ribosomal proteins (21% of all annotated ribosomal protein genes during early- and 14% during late-exponential) and tRNA genes (14% of all annotated tRNA genes in early-exponential), indicating a marked decrease in protein translation. Other significant changes were the upregulation of membrane transporters, implying an increase in the traffic of substrates across the cell membrane, as well as the up and downregulation of genes related to respiration, which could be interpreted as a response to insufficient oxidants in the cells. …”

<em>Shewanella</em> spp. Genomic Evolution for a Cold Marine Lifestyle and <em>In-Situ</em> Explosive Biodegradation by Jian-Shen Zhao (253637)

“…<div><p><em>Shewanella halifaxensis</em> and <em>Shewanella sediminis</em> were among a few aquatic γ-proteobacteria that were psychrophiles and the first anaerobic bacteria that degraded hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). …”

A phage promoter can substitute for the <i>pilE</i> G4-associated sRNA promoter. by Laty A. Cahoon (102333)

“…Expression of T7 polymerase at the NICS (NICS T7 Pol.) does not affect phase variation whereas replacement of the G4 sRNA promoter with a minimal T7 promoter (T7 Prom.) causes a decrease in phase variation which is rescued by expression of T7 polymerase at the NICS (T7 Prom.…”

Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects by Marie-Laure Crouch (405007)

“…We found that exposed mice developed a persistent decrease in treadmill running time compared to baseline (25.7±10.6 vs. 49.0±16.8 min, <i>P</i> = 0.0012). …”

Table1_Example for process validation in biobanking: Fit for purpose testing of a cryopreservation method without isopentane.DOCX by Monika Wieser (13886388)

“…The freezing method was robust for the tested tissue types and the application of OCT, with exception of liver tissue, where it led to a significant decrease of the RIN value. Gene expression analyzes showed good comparability of results regardless of the applied freezing method.…”

Table_6_Trichohyalin gene expression is negatively correlated with the severity of dermatitis in a canine atopic dermatitis model.XLSX by Rosanna Marsella (8606172)

“…Introduction<p>Canine atopic dermatitis (AD) closely mimics human AD and is recognized as a beneficial animal model. House dust mites (HDM) are a common allergen for both species. …”

Cycle Checkpoint Abnormalities during Dementia: A Plausible Association with the Loss of Protection against Oxidative Stress in Alzheimer’s Disease by Pavel Katsel (257692)

“…In addition to gene expression changes, the downstream target of ATM-p53 signaling - TIGAR, a p53-inducible protein, the activation of which can regulate energy metabolism and protect against oxidative stress was progressively decreased as severity of dementia evolved, but it was unaffected in subjects with SZ. …”

Data_Sheet_1_Evaluation of Metagenomic-Enabled Antibiotic Resistance Surveillance at a Conventional Wastewater Treatment Plant.PDF by Haniyyah J. Majeed (10792509)

“…Relative abundance of total ARGs decreased by ∼50% from the influent to the effluent, with each sampling location defined by a unique resistome (i.e., total ARG) composition. …”