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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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54861
Theoretical Mechanistic Insights into Dinitrogen Activation by a Diniobium Tetrahydride: Two-State Reactivity and the Role of Potassium Cation Promoter
Published 2020“…Remarkably, it is revealed that alkali metal cations play a crucial role via alkali···N coordination interaction, which is capable of decreasing the activation barriers of N–H formation and subsequent H<sub>2</sub> elimination in particular. …”
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54862
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54863
Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in <i>Caenorhabditis elegans</i>
Published 2017“…We conclude that cytosolic redox established through the PPP is a key regulator of mitochondrial function and defines a new mechanism for mitochondrial regulation of longevity.…”
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54864
Video 5_Transcatheter mitral valve replacement to treat rheumatic mitral stenosis: a case series.mp4
Published 2024“…Background<p>Rheumatic mitral stenosis (RMS) is a common valvular heart disease in developing countries. …”
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54865
Image1_Trimetazidine Modulates Mitochondrial Redox Status and Disrupted Glutamate Homeostasis in a Rat Model of Epilepsy.JPEG
Published 2021“…<p>Mitochondrial oxidative status exerts an important role in modulating glia–neuron interplay during epileptogenesis. Trimetazidine (TMZ), a well-known anti-ischemic drug, has shown promising potential against a wide range of neurodegenerative disorders including epilepsy. …”
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54866
Data Sheet 2_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf
Published 2025“…Frequently mentioned metabolites were subjected to enrichment analysis using the MetaboAnalyst 6.0 platform.</p>Results<p>A total of 51 studies were included. Quality assessment revealed that 54.8% of the diagnostic studies and 69.2% of the prognostic studies were high-quality, with most controlling for confounding factors. …”
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54867
Transcriptional changes in COL.<i>w</i>Mel relative to COL.tet following a ZIKV-infected bloodmeal.
Published 2023“…<p><b>(A)</b> Volcano plots showing differentially expressed transcripts in midgut and carcass tissues at 4 and 7 dpf after a ZIKV-infected bloodmeal, highlighting <i>Aedes aegypti</i> predicted innate immune genes (highlighted in magenta). …”
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54868
Data_Sheet_1_A Bispecific Antibody-Based Approach for Targeting Mesothelin in Triple Negative Breast Cancer.docx
Published 2019“…Its overexpression in breast tumors has been recently correlated with a decreased disease-free survival and an increase of distant metastases. …”
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54869
Data_Sheet_1_Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.doc
Published 2019“…</p><p>Methods: A detailed analysis protocol was registered at the PROSPERO database prior to data extraction (CRD42018110798). …”
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54870
Supplementary Material for: Resistance Exercise Improves Mitochondrial Quality Control in a Rat Model of Sporadic Inclusion Body Myositis
Published 2019“…Most importantly, the decreased Aβ accumulation improved both mitochondrial quality control (MQC) through increased mitochondrial biogenesis and mitophagy, and mitochondrial dynamics. …”
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54871
<b>Litter decomposition regulated by stand ECM dominance but not litter mycorrhizal type in a subtropical mountainous forest</b>
Published 2025“…In the initial one month, leaf dry matter content (LDMC) was the most important factor.</a> AM and ECM litter decomposition in plots with a natural gradient of ECM tree dominance showed that the decomposition rates of both AM litter and ECM litter decreased significantly in plots with increasing ECM dominance. …”
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54872
DataSheet1_Efficacy and safety of levetiracetam for migraine prophylaxis in children: a systematic review and meta-analysis.pdf
Published 2024“…More than 83% experienced a >50% reduction in monthly headache frequency. …”
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54873
A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe
Published 2016“…Moreover, our results shown that a transient activation of the nuclear factor κB (NFκB) occurred early in these cells, but decreased after 6 h of the treatment, explaining in part the diminution of the anti-apoptotic proteins. …”
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54874
Cell number of early embryos determines the formation of type <i>a</i> and type <i>b</i> blastocysts.
Published 2014“…(C) A type <i>b</i> 4n blastocyst from 4C-1 embryos showing the decreased cell number and missing the ICM. …”
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54875
Osteocyte Network; a Negative Regulatory System for Bone Mass Augmented by the Induction of Rankl in Osteoblasts and Sost in Osteocytes at Unloading
Published 2012“…<div><p>Reduced mechanical stress is a major cause of osteoporosis in the elderly, and the osteocyte network, which comprises a communication system through processes and canaliculi throughout bone, is thought to be a mechanosensor and mechanotransduction system; however, the functions of osteocytes are still controversial and remain to be clarified. …”
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54876
Image_5_The Design, Characterizations, and Tumor Angiogenesis Inhibition of a Multi-Epitope Peptibody With bFGF/VEGFA.TIF
Published 2021“…In in vitro experiments, the isolated anti-Peptibody antibody inhibited the proliferation and migration of A549 cells and human umbilical vein endothelial cells (HUVECs) by decreasing the MAPK/Akt/mTOR signal pathways. …”
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54877
Image_3_The Design, Characterizations, and Tumor Angiogenesis Inhibition of a Multi-Epitope Peptibody With bFGF/VEGFA.TIF
Published 2020“…In in vitro experiments, the isolated anti-Peptibody antibody inhibited the proliferation and migration of A549 cells and human umbilical vein endothelial cells (HUVECs) by decreasing the MAPK/Akt/mTOR signal pathways. …”
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54878
Data Sheet 1_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf
Published 2025“…Frequently mentioned metabolites were subjected to enrichment analysis using the MetaboAnalyst 6.0 platform.</p>Results<p>A total of 51 studies were included. Quality assessment revealed that 54.8% of the diagnostic studies and 69.2% of the prognostic studies were high-quality, with most controlling for confounding factors. …”
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54879
Video_1_Immunohistochemical Evaluation of Histological Change in a Chinese Milroy Disease Family With Venous and Skin Abnormities.MOV
Published 2019“…</p><p>Methods: Here we report a Chinese MD family with 2 affected members of two generations. …”
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54880
Image_6_The Design, Characterizations, and Tumor Angiogenesis Inhibition of a Multi-Epitope Peptibody With bFGF/VEGFA.TIF
Published 2020“…In in vitro experiments, the isolated anti-Peptibody antibody inhibited the proliferation and migration of A549 cells and human umbilical vein endothelial cells (HUVECs) by decreasing the MAPK/Akt/mTOR signal pathways. …”