Supplementary Material for: Efficacy of Huanglian Jiedu Decoction for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis by Wang M. (3632518)

“…Furthermore, combination therapy enhanced the efficacy rate and favorably altered lipid profiles, including increasing HDL-C and decreasing LDL-C, TC, and TG levels. It was worth noting that the results of the subgroup analysis indicated that, in terms of reducing HbA1c and 2hPG, the efficacy of HJD alone for a duration of less than 3 months was found to be potentially superior to that observed in treatments exceeding 3 months. …”

Table_1_v2_Beyond aroma: A scoping review on the impact of chronic rhinosinusitis on retronasal olfaction.docx by Joel James (771227)

“…Of six studies evaluating the relationship between retronasal and orthonasal olfactory test scores in CRS patients two out of six (33%) demonstrated a correlation between both forms of olfaction and CRS, and two out of six studies (33%) found significantly lower orthonasal olfactory test scores compared to retronasal olfactory test scores. …”

Image 5_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.tif by Hong-Xing Li (316258)

“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”

Image_2_TNFR2 Is a Crucial Hub Controlling Mesenchymal Stem Cell Biological and Functional Properties.TIFF by Ghada Beldi (9730292)

“…In this article, we have explored the importance of TNFR2 expression in a series of MSCs’ biological and functional properties. …”

<i>P. expansum</i> exhibited a limited loss of plasma membrane integrity, but displayed protein oxidative damage. by Guozheng Qin (214834)

“…<p>(A) H₂O₂ treatment decreases the percentage of fungal survival. …”

Data_Sheet_1_Sphingomyelin and Medullary Sponge Kidney Disease: A Biological Link Identified by Omics Approach.PDF by Simona Granata (477257)

“…<p>Background: Molecular biology has recently added new insights into the comprehension of the physiopathology of the medullary sponge kidney disease (MSK), a rare kidney malformation featuring nephrocalcinosis and recurrent renal stones. …”

Recruitment of RED-SMU1 Complex by Influenza A Virus RNA Polymerase to Control Viral mRNA Splicing by Guillaume Fournier (577584)

“…We demonstrate that the splicing of the NS1 viral mRNA is specifically affected in cells depleted of RED or SMU1, leading to a decreased production of the spliced mRNA species NS2, and to a reduced NS2/NS1 protein ratio. …”

DataSheet4_Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway.ZIP by Ting Zeng (1521649)

“…Transcriptome sequencing and bioinformatics analysis results showed that in cobll1a knockout group, the expression level of genes in the Retinoic Acid (RA) signaling pathway was affected, and the expression level of lipid metabolism-related genes (fasn, scd, elovl2, elovl6, dgat1a, srebf1 and srebf2) were significantly changed (p < 0.01), leading to increased lipid synthesis and decreased lipid catabolism. …”

Table_1_Case report: Sympathetic ophthalmia after vitrectomies in a patient with Von Hippel–Lindau syndrome.XLS by Xiaonan Zhuang (14604530)

“…</p>Case presentation<p>A 21-year-old woman suffered from decreased vision in the right eye and was diagnosed with retinal capillary hemangioblastomas associated with Von Hippel–Lindau syndrome. …”

Table_2_Gut microbiota composition in travellers is associated with faecal lipocalin-2, a mediator of gut inflammation.csv by Javier Gandasegui (778298)

“…Differential abundance (DA) testing highlighted a microbial profile tied to high LCN2 levels, marked by increased Proteobacteria and Escherichia-Shigella, and decreased Firmicutes, notably Oscillospiraceae. …”

DataSheet_1_A Novel Homozygous Mutation Destabilizes IKKβ and Leads to Human Combined Immunodeficiency.zip by Tao Qin (177288)

“…Targeted gene panel sequencing revealed a novel homozygous missense mutation in the IKBKB gene of a patient with immune dysregulation and combined T and B cell functional defects. …”

Presentation_1_Assessing the importance of kelp forests for small-scale fisheries under a global change scenario.pdf by Cristina Piñeiro-Corbeira (10021615)

“…On the other hand, compared to two decades ago, fishers reported a substantial contraction in the area occupied by kelp forests and decreases in the fisheries typically associated with this habitat. …”

Supplementary materials: Recommendations from Cochrane reviews for improving future trials on anesthesia and pain: a meta-research study by Renata Runjic (18500446)

“…<p dir="ltr"><b>These are peer-reviewed supplementary materials for the article '</b><b>Recommendations from Cochrane reviews </b><b>for improving future trials on anesthesia </b><b>and pain: a meta-research study</b><b>' published in the</b><b> </b><b><i>Journal of Comparative Effectiveness Research</i></b><b>.…”

Table_1_Effects of SGLT2 inhibitors on hepatic fibrosis and steatosis: A systematic review and meta-analysis.docx by Peipei Zhou (838409)

“…Further subgroup analyses indicated that SGLT2i presented more advantages on longer treatment duration and more serious steatosis in decreasing LSM. For CAP, SGLT2i exhibited a clear advantage in subgroup analyses of longer treatment duration, younger people, dapagliflozin, worse fibrosis, and steatosis.…”

Supplementary Material for: The EFEMP1 Gene: A Frequent Target for Epigenetic Silencing in Multiple Human Pituitary Adenoma Subtypes by Duong C.V. (3835249)

“…<strong><em>Background/Aims:</em></strong> In a genome-wide investigation we recently identified the EGF-containing fibulin-like extracellular matrix protein 1 gene, <i>EFEMP1</i>, as hypermethylated in growth hormone-secreting adenoma. …”

Image_4_A Novel Mice Model for Studying the Efficacy and IRAEs of Anti-CTLA4 Targeted Immunotherapy.tif by Shengchao Xu (5715461)

“…Background<p>Patient-derived orthotopic xenograft (PDOX) is a popular animal model for translational cancer research. …”

Table 1_Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies.docx by Zhongmei Fu (11869694)

Image_1_Iron status and obesity-related traits: A two-sample bidirectional Mendelian randomization study.pdf by Zengyuan Zhou (6381080)

“…In this study, we performed a two-sample bidirectional Mendelian randomization analysis to investigate the causal link between iron status and obesity-related traits.…”

Experiences of Community-Living Older Adults Receiving Integrated Care Based on the Chronic Care Model: A Qualitative Study by Sophie L. W. Spoorenberg (816772)

“…The prospect of becoming dependent and losing control was a key concept in the lives of the older adults interviewed. …”

DataSheet5_Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway.docx by Ting Zeng (1521649)

“…Transcriptome sequencing and bioinformatics analysis results showed that in cobll1a knockout group, the expression level of genes in the Retinoic Acid (RA) signaling pathway was affected, and the expression level of lipid metabolism-related genes (fasn, scd, elovl2, elovl6, dgat1a, srebf1 and srebf2) were significantly changed (p < 0.01), leading to increased lipid synthesis and decreased lipid catabolism. …”