Data_Sheet_3_Biomechanical Response of the Lower Extremity to Running-Induced Acute Fatigue: A Systematic Review.docx by Salil Apte (5431346)

“…From the 42 parameters identified in response to acute fatigue, flight time, contact time, knee flexion angle at initial contact, trunk flexion angle, peak tibial acceleration, CoP velocity during balance test showed an increasing behavior and cadence, vertical stiffness, knee extension force during MVC, maximum vertical ground reaction forces, and CMJ height showed a decreasing trend across different fatigue protocols.…”

Image_2_Lutzomyia longipalpis TGF-β Has a Role in Leishmania infantum chagasi Survival in the Vector.JPEG by Tatiana Di-Blasi (4680811)

“…The blockage of the LlTGF-β pathway increased significantly antimicrobial peptides expression and nitric oxide levels in the insect gut, as expected. Both methods led to a decreased L. i. chagasi infection. Our results show that inactivation of the L. longipalpis TGF-β signal transduction pathway reduce L. i. chagasi survival, therefore suggesting that under natural conditions the parasite benefits from the insect LlTGF-β pathway, as already seen in Plamodium infection of mosquitoes.…”

Table4_Impact of systemic lupus erythematosus on cardiovascular morphologic and functional phenotypes: a Mendelian randomization analysis.xlsx by Zishan Lin (14501705)

“…</p>Results<p>SLE exhibited a correlation with increased stroke volume (β_LVSV = 0.007, P = 0.045), regional peak circumferential strain (β_{Ecc_AHA_9} = 0.013, P = 0.002; β_{Ecc_AHA_12} = 0.009, P = 0.043; β_{Ecc_AHA_14} = 0.013, P = 0.006), and global peak circumferential strain of the LV (β_{Ecc_global} = 0.010, P = 0.022), as well as decreased regional radial strain (β_{Err_AHA_11} = −0.010, P = 0.017).…”

Table_2_Effects of Flavonoid Supplementation on Nanomaterial-Induced Toxicity: A Meta-Analysis of Preclinical Animal Studies.DOCX by Dongli Xie (400786)

“…STATA 15.0 software was used for meta-analyses.</p>Results<p>A total of 26 studies were identified. The results showed that flavonoid supplementation could significantly increase the levels of antioxidative enzymes (superoxide dismutase, catalase, glutathione, glutathione peroxidase, and glutathione-S-transferase), reduce the production of oxidative agents (malonaldehyde) and pro-inflammatory mediators (tumor necrosis factor-α, interleukin-6, IL-1β, C-reactive protein, immunoglobulin G, nitric oxide, vascular endothelial growth factor, and myeloperoxidase), and alleviate cell apoptosis (manifested by decreases in the mRNA expression levels of pro-apoptotic factors, such as caspase-3, Fas cell surface death receptor, and Bax, and increases in the mRNA expression levels of Bcl2), DNA damage (reductions in tail length and tail DNA%), and nanomaterial-induced injuries of the liver (reduced alanine aminotransferase and aspartate aminotransferase activities), kidney (reduced urea, blood urea nitrogen, creatinine, and uric acid concentration), testis (increased testosterone, sperm motility, 17β-hydroxysteroid dehydrogenase type, and reduced sperm abnormalities), and brain (enhanced acetylcholinesterase activities). …”

Table 7_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Background<p>Osteomyelitis, a persistent inflammatory bone disease, is only partially responsive to conventional antibiotics and surgery. …”

Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy by Mayank Verma (314207)

“…<div><p>Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disease in which the dystrophin coding for a membrane stabilizing protein is mutated. Recently, the vasculature has also shown to be perturbed in DMD and DMD model <i>mdx</i> mice. …”

Data_Sheet_1_Biomechanical Response of the Lower Extremity to Running-Induced Acute Fatigue: A Systematic Review.xlsx by Salil Apte (5431346)

“…From the 42 parameters identified in response to acute fatigue, flight time, contact time, knee flexion angle at initial contact, trunk flexion angle, peak tibial acceleration, CoP velocity during balance test showed an increasing behavior and cadence, vertical stiffness, knee extension force during MVC, maximum vertical ground reaction forces, and CMJ height showed a decreasing trend across different fatigue protocols.…”

A new elasmosaurid (Plesiosauria: Sauropterygia) from the López de Bertodano Formation: new data on the evolution of the aristonectine morphology by Jose P. O’Gorman (8570223)

“…The phylogenetic analysis recovers <i>M. molinai</i> gen. et sp. nov. within the Weddellonectia and as a sister group of aristonectines, indicating that the process of decreasing cervical vertebrae numbers, wide symphyseal sulcus and atlas-axis complex with circular atlantal cup and low and rounded hypapophyseal keel started previous to the appearance of aristonectines. …”

Video1_Journey through a virtual tunnel: Simulated motion and its effects on the experience of time.MP4 by Maximilian Landeck (11151309)

“…Previous work has shown that the perception of motion can affect the perception of time. We developed a virtual environment that simulates motion in a tunnel and measured its effects on the estimation of the duration of time, the speed at which perceived time passes, and the illusion of self-motion, also known as vection. …”

Table 5_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Background<p>Osteomyelitis, a persistent inflammatory bone disease, is only partially responsive to conventional antibiotics and surgery. …”

Supplementary Material for: Association of MTHFR gene with type 2 diabetes mellitus: A case-control study and meta-analysis by figshare admin karger (2628495)

“…Results: In case-control study at the C677T(rs1801133), we found that compared with the AA genotype, GG + GA genotype was associated with an increased risk of T2DM (OR=1.605; 95% CI: 1.229–2.095; P=0.001); compared with the GG/GA genotype, AA genotype was associated with a decreased risk of T2DM (OR=0.620; 95% CI: 0.450–0.855; P=0.004; OR=0.625; 95% CI: 0.470–0.830; P=0.001). …”

Table_1_Refractory Ileal Perforations in a Cytomegalovirus-Infected Premature Neonate Resolved After Ganciclovir Therapy.docx by Mari Morimoto (9118313)

“…CMV-DNA was also detected in the dried umbilical cord which was obtained within a week from birth. A 6-week course of intravenous ganciclovir (12 mg/kg/day) was started at DOL34 and then symptoms resolved along with decreasing blood CMV-DNA. …”

Table4_Transcriptomics reveals a distinct metabolic profile in T cells from severe allergic asthmatic patients.xlsx by Carmela Pablo-Torres (10192451)

“…Severe allergic asthmatic patients presented downregulation in genes related to oxidative phosphorylation, fatty acid oxidation and glycolysis together with increased expression of genes coding inflammatory cytokines (e.g. IL-19, IL-23A and IL-31). Moreover, the downregulation of genes involved in TGFβ pathway together with a decreased tendency on the percentage of T regulatory cell (CD4 + CD25+), suggest a compromised regulatory function in severe allergic asthmatic patients. …”

Data_Sheet_1_Causal Relationship Between Parathyroid Hormone and the Risk of Osteoarthritis: A Mendelian Randomization Study.docx by Guiwu Huang (11183319)

“…</p>Conclusion<p>MR analysis supported a potential causative relationship between decreased serum circulating PTH and a higher risk of hip and knee OA.…”

Image_1_Causality between Ankylosing Spondylitis and osteoarthritis in European ancestry: a bidirectional Mendelian randomization study.tif by Yangguang Lu (17906228)

“…MR results revealed that individuals with AS exhibit a decreased risk of knee OA (OR = 0.9882, 95% CI: 0.9804-0.9962) but no significant increase in the risk of hip OA (OR = 0.9901, 95% CI: 0.9786-1.0018). …”

Table_3_Causality between Ankylosing Spondylitis and osteoarthritis in European ancestry: a bidirectional Mendelian randomization study.docx by Yangguang Lu (17906228)

“…MR results revealed that individuals with AS exhibit a decreased risk of knee OA (OR = 0.9882, 95% CI: 0.9804-0.9962) but no significant increase in the risk of hip OA (OR = 0.9901, 95% CI: 0.9786-1.0018). …”

Data Sheet 1_Unveiling nitrogen preferences in indica rice: a classification study of cultivars in South China.pdf by Chu-sheng Lu (21188636)

“…</p>Result<p>Compared to ammonium-only nutrition, a mixed ammonium-nitrate treatment significantly boosted root and shoot growth, while nitrate-only nutrition led to a decline in chlorophyll content. …”

Table_1_Prevalence and effect on survival of pre-treatment sarcopenia in patients with hematological malignancies: a meta-analysis.doc by Jianzhu Xiong (17106295)

“…Background & aims<p>Evidence regarding the prevalence of pre-treatment sarcopenia and its impact on survival in patients with hematological malignancies (HM) varies across studies. We conducted a systematic review and meta-analysis to summarize this discrepancy.…”

Image6_Efficacy of propofol for the prevention of emergence agitation after sevoflurane anaesthesia in children: A meta-analysis.tif by Yinggang Xiao (13896222)

“…</p>Discussion<p>We confirmed that a prophylactic dose of propofol prevented EA and decreased its severity in children under sevoflurane anesthesia. …”

Image_1_A population of dermal Langerin+ dendritic cells promote the inflammation in mouse model of atopic dermatitis.tif by Chunying Xiao (8612091)