Effect of set up protocols on the accuracy of alchemical free energy calculation over a set of ACK1 inhibitors by José M. Granadino-Roldán (6449285)

“…The main finding is that use of knowledge derived from X-ray structures to model binding modes, together with the manual placement of a bridging water molecule, improves the R² from 0.45 ± 0.06 to 0.76 ± 0.02 and decreases the mean unsigned error from 2.11 ± 0.08 to 1.24 ± 0.04 kcal mol^-1. …”

Image_2_Effects of SGLT2 inhibitors on hepatic fibrosis and steatosis: A systematic review and meta-analysis.jpeg by Peipei Zhou (838409)

“…Further subgroup analyses indicated that SGLT2i presented more advantages on longer treatment duration and more serious steatosis in decreasing LSM. For CAP, SGLT2i exhibited a clear advantage in subgroup analyses of longer treatment duration, younger people, dapagliflozin, worse fibrosis, and steatosis.…”

Table1_Effectiveness and safety of tripterygium wilfordii poly-glycosides on glomerulonephritis: a systematic review and meta-analysis.docx by Xiaolin Yan (3796822)

“…Analysis revealed that additional TWP administration improved patients’ outcomes and total remission rates, reduced 24-h urine protein (24hUP) and decreased relapse events. The pooled results demonstrated the non-inferiority of TWP to glucocorticoids in achieving total remission, reducing 24hUP, and converting the phospholipase A2 receptor (PLA2R) status to negative. …”

Image_1_Alterations of gut microbiota in cirrhotic patients with spontaneous bacterial peritonitis: A distinctive diagnostic feature.tif by Zumo Zhou (293879)

“…Background<p>Spontaneous bacterial peritonitis (SBP) is a severe infection in cirrhotic patients that requires early diagnosis to improve the long-term outcome. …”

Charge Density-Regulated Microchannel-Based Electrochemiluminescence Sensor for Hydrogen Sulfide Detection with a Highly Efficient Accumulation Strategy by Yanling Huang (577654)

“…The interaction of azide groups and hydrogen sulfide served as a research model. Hydrogen sulfide can react with the negatively charged azide groups in the microchannel surface to produce positively charged amino groups, decreasing the negative charge density of the microchannel and thus altering the ionic current and ECL intensity. …”

Making Cells as a “Nirvana Phoenix”: Precise Coupling of Precursors Prior to ROS Bursts for Intracellular Synthesis of Quantum Dots by Juan Kong (2230867)

“…Such a comprehensive control strategy can inhibit the production of cytotoxic Se species and ROS bursts, significantly increasing the cell viability from 4 to 80% and enhancing the fluorescence of intracellularly synthesized Ag₂Se QDs by over 8.7 times. …”

Image_1_Effectiveness of a novel compound microbial agent for water quality and the gut microbiota of Micropterus salmoides.tif by Qian Li (114642)

“…<p>The cultivation of largemouth bass (Micropterus salmoides), a species of significant economic value in aquaculture, has experienced notable growth recently. …”

DataSheet_1_MXSGD alleviates CsA-induced hypoimmunity lung injury by regulating microflora metabolism.pdf by Chun Ye (265823)

“…Context<p>Ma Xing Shi Gan Decoction (MXSGD) is a traditional remedy for treating lung injuries that was developed by the Typhoid and Fever School of Pharmaceutical Biology. …”

Data_Sheet_1_A Novel Microglia-Specific Transcriptional Signature Correlates With Behavioral Deficits in Neuropsychiatric Lupus.pdf by Hadijat M. Makinde (5791190)

“…NP-SLE microglia exhibit numerical expansion, increased synaptic uptake, and a more metabolically active phenotype. Microglia from multiple SLE-prone models express a “NP-SLE signature” unrelated to type I interferon. …”

DataSheet_1_Causal effects of gut microbiota on the risk of bipolar disorder: a Mendelian randomization study.zip by Ran Xu (316855)

“…Background<p>Recent studies have suggested a possible association between gut microbiota and bipolar disorder (BD). …”

Experimental Investigation on the Dynamics of On-Demand Ferrofluid Drop Formation under a Pulse-Width-Modulated Nonuniform Magnetic Field by Mohamad Ali Bijarchi (9007640)

“…Also, the effect of the duty cycle, the induced frequency, the magnetic induction, and the vertical interval between the coil’s top surface and the nozzle on the drop formation evolution, the equivalent diameter of the droplets, the frequency of droplet formation, and the pulses that are necessary to form a drop was studied. Additionally, it was illustrated that by prolonging the duty cycle, the magnetic induction, or by decreasing the induced frequency, the equivalent diameter of the drop and the pulses that are necessary to form a drop reduce, while the frequency of drop formation increases. …”

Space-time variations in child mortality in a rural South African population with high HIV prevalence (2000–2014) by Boikhutso Tlou (4390138)

“…Childhood mortality decreased by 80% over the period from >20 per 1000 person-years in 2001–2003 to 4 per 1000 person-years in 2014. …”

Supplementary Material for: Unravelling Pathophysiology of Crystalline Nephropathy in Ceftriaxone-Associated Acute Kidney Injury: A Cellular Proteomic Approach by Chatchen S. (4767918)

“…<b><i>Results:</i></b> Phase-contrast microscopy showed increased intracellular vesiculation and cell enlargement as a result of ceftriaxone crystal exposure. Proteome analysis revealed a total of 20 altered proteins (14 increased, 5 decreased and 1 absent) in ceftriaxone crystal-treated MDCK cells as compared to untreated cells (<i>p</i> < 0.05). …”

Accuracy of molecular biology techniques for the diagnosis of <i>Strongyloides stercoralis</i> infection—A systematic review and meta-analysis by Dora Buonfrate (101978)

“…<div><p>Background</p><p><i>Strongyloides stercoralis</i> infection is a neglected tropical disease which can lead to severe symptoms and even death in immunosuppressed people. …”

Table 2_PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment.xlsx by Hong-Xing Li (316258)

“…Objective<p>This study aimed to investigate the role of poly(A) binding protein nuclear 1 (PABPN1) as a potential pan-cancer biomarker for prognosis and immunotherapy.…”

Experimental Investigation on the Dynamics of On-Demand Ferrofluid Drop Formation under a Pulse-Width-Modulated Nonuniform Magnetic Field by Mohamad Ali Bijarchi (9007640)

“…Also, the effect of the duty cycle, the induced frequency, the magnetic induction, and the vertical interval between the coil’s top surface and the nozzle on the drop formation evolution, the equivalent diameter of the droplets, the frequency of droplet formation, and the pulses that are necessary to form a drop was studied. Additionally, it was illustrated that by prolonging the duty cycle, the magnetic induction, or by decreasing the induced frequency, the equivalent diameter of the drop and the pulses that are necessary to form a drop reduce, while the frequency of drop formation increases. …”

Making Cells as a “Nirvana Phoenix”: Precise Coupling of Precursors Prior to ROS Bursts for Intracellular Synthesis of Quantum Dots by Juan Kong (2230867)

“…Such a comprehensive control strategy can inhibit the production of cytotoxic Se species and ROS bursts, significantly increasing the cell viability from 4 to 80% and enhancing the fluorescence of intracellularly synthesized Ag₂Se QDs by over 8.7 times. …”

Image_1_‘TIME’: A Web Application for Obtaining Insights into Microbial Ecology Using Longitudinal Microbiome Data.PDF by Krishanu D. Baksi (7381298)

“…A number of these microbiome studies have focused on understanding changes in the microbial community over time. …”

Switchable Dielectric Phase Transition with Drastic Symmetry Breaking in a Sn(IV)-Based Perovskite-Type Halide Semiconductor by Xiu-Ni Hua (1678858)

“…Variable-temperature structure analyses disclose that the drastic symmetry breaking occurs with the structure transferring from <i>Fm</i>3̅<i>m</i> to <i>C</i>2/<i>c</i> by the temperature decreasing. The mechanism of such a transition is associated with the order–disorder transformation of organic ammonium and the displacement of the inorganic framework, which benefits from the discrete anionic architectures that provide enough space. …”

Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials by Sofía Tejada (10699920)

“…A positive trend favored antivirals administration to reduce pneumonia (OR:0.47, 95%CI: 0.16–1.33), or hospitalization rates (OR:0.65; 95%CI: 0.34–1.24) compared to placebo, but did not reach statistical significance. …”