Showing 9,561 - 9,580 results of 226,405 for search '(( a ((a decrease) OR (linear decrease)) ) OR ( a ((largest decrease) OR (greater decrease)) ))', query time: 1.13s Refine Results
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    Data Sheet 1_Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD.docx by Hyun-ju Lee (7550741)

    Published 2025
    “…Finally, hippocampal DYRK1A knockdown in PS19 mice [a model of AD that overexpresses human mutant tau (P301S)] selectively decreased insoluble tau hyperphosphorylation at Ser396 and Ser404 and alleviated proinflammatory responses/glial-associated neuroinflammatory dynamics. …”
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    Stability scores with refinement, no USM decreases, no W. by Jedediah M. Singer (10331212)

    Published 2022
    “…<p>Effects of guided and random substitutions within GM designs with a maximum sequence identity to any expert-designed protein of less than 50%, when guided substitutions are not permitted to decrease USM EC<sub>50</sub> predictions and neither guided nor random substitutions are allowed to change amino acids to tryptophan.…”
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