Macrophages Have Distinct Transcriptional Responses to Vacuolar and Cytosolic L. monocytogenes Infection by Jess H Leber (4401)

“…Red indicates an increase in RNA abundance relative to uninfected macrophages, and green indicates a decrease. Genes identified by SAM and at least 4-fold induced in WT macrophages by <i>hly− L. monocytogenes</i> are indicated as targets of the “Vacuolar Response”. …”

Detailed agreement between ¹³C CEST, smFRET, SAXS, and SEC elution profiles with the generalized Manning model corroborates pre-organization by Mg²⁺. by Susmita Roy (589965)

“…(i) Compaction of SAM-II as a function of [Mg²⁺] obtained from SEC elution profiles is consistent with a decrease in hydrodynamic radius (experimental data adapted from ref. 40), [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005406#pcbi.1005406.ref040" target="_blank">40</a>] in qualitative agreement with the observed folding transition in the average radius of gyration (Rg) obtained from equilibrium simulations at Mg_1/2≈6.0 mM.…”

DataSheet1_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.PDF by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

Cost-utility of 20-valent pneumococcal conjugate vaccine compared to no vaccination and recommended alternative vaccines among Belgian adults by Sophie Marbaix (5488280)

“…This cost-effectiveness analysis indicates that use of PCV20 will help decrease the number of pneumococcal disease cases, hospitalizations, and premature deaths at an affordable healthcare cost: PCV20 is a cost-effective option compared to no vaccination and a cost-saving option compared to the sequential regimen PCV15 followed by PPV23 in the Belgian adult population recommended for pneumococcal vaccination.…”

DataSheet3_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.PDF by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

Image_2_Impact of in-utero exposure to HIV and latent TB on infant humoral responses.jpeg by Kimberly J. S. Hjelmar (18890608)

“…All infants showed a decrease in IgG to viral antigens (HIV GP120 and HA) from 12 to 44 weeks attributed to waning of maternally transferred antibody titers. …”

Table_1_Correlation between dietary factors and Parkinson’s disease revealed by the analysis of Mendelian randomization.XLSX by Shan Zeng (3464564)

“…Employing MR, specifically the IVW method, revealed a significant inverse association between bap intake and gut microbiota, marked by an 8.010-fold decrease in Parabacteroides goldsteinii per standard deviation increase in bap intake (95% CI 1.005–63.818, p = 0.049). …”

Reduction of BMP-signaling in <i>Fgf3</i> mutants partially rescues axis extension. by Matthew J. Anderson (265883)

“…<i>Fgf3</i>^<i>Δ/Δ</i><i>; Bmpr1b</i>^<i>Δ/Δ</i> compound mutants, compared to <i>Fgf3</i>^<i>Δ/Δ</i> mutants show a narrower, more normal neural tube at 28 ss (<b>B</b> compare to <b>A</b>; <b>black brackets</b> indicate measurement of NT width, quantified in <b>C</b>), a decrease in neuroectoderm proliferation as measured by phospho-histone H3 staining (<b>D</b>, 26–27 ss, n = 3 each, percentage represents positive nuclei per total nuclei), an increase in tailbud progenitors (<b>F</b> compare to <b>E</b>; <b>black arrows</b> denote tailbud progenitor domain) and a rostrally shifted, more normal, posterior limit of neural crest cells at 34 ss (<b>H</b> compare to <b>G</b>; <b>red arrows</b> indicate posterior limit of neural crest expansion and somites are marked by <b><i>Uncx4</i>.1</b> expression). …”

Feedback coupling among reactions and structural transitions in KaiC hexamer. by Masaki Sasai (25828)

“…KaiA unbinds from the CII of the <i>X</i> ≈ 0 KaiC, promoting the dP process to decrease <i>D</i>. …”

Homolog pairing and sister chromatid cohesion in interphase remain unaffected genome-wide after knockdown of Rad21. by T. Niroshini Senaratne (3067776)

“…A simple separation of sister chromatids would be expected to cause a decrease in the percentage of nuclei with a single FISH signal, or an increase in the area of FISH signals; we observed neither (see main text for details).…”

<b>Supporting data for ‘Identification and Characterization of Viral and Host Factors Determining Virus Replication Fitness</b><b>’</b> by Ronghui Liang (9151553)

“…The research revealed that the modulation of D-mannose flux rewires the virus-triggered immunometabolic response cascade, thereby reducing tissue damage. From a mechanistic perspective, D-mannose slows down glycolysis, which in turn limits the production of mitochondrial reactive oxygen species and succinate-mediated hypoxia-inducible factor-1α signal pathway, consequently leads to a decrease in proinflammatory cytokine production incited by the virus. …”

Effect of reducing Dscam1 expression level on the phenotype–diversity correlations. by Haiyang Dong (4783608)

“…<b>(H)</b> The normal phenotypes in mutants expressing a single exon 9.1 improved with the decrease in the Dscam1 expression level. …”

Experience-dependent and temporally restricted serotonin signaling and synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…Two-way ANOVA with Tukey’s multiple comparison shows a highly significant decrease in the Or42a OSN innervation (<i>n</i> = 28/condition, <i>p</i> = 7.45 × 10⁻¹¹) and increase in serotonin (<i>n</i> = 28/condition, <i>p</i> = 4.10 × 10⁻¹⁴). …”

Overlapping concepts can be retrieved separately and jointly. by Chiara Gastaldi (7857911)

“…Arrows indicate direction and speed of increase or decrease of the similarity variables. Intersections of blue and orange lines (the “nullclines” of the two variables <i>m</i>¹, <i>m</i>²) indicate fixed points, with a stability encoded by color (legend). …”

The C₇H₆ Potential Energy Surface Revisited: Relative Energies and IR Assignment by Stephan Matzinger (2538523)

“…The relative energies and the nature of the different <b>CHT</b> stationary points depend on the method of calculation, but it appears that the decrease in electron repulsion lowers the ¹A₂ state slightly below the ¹A₁ state so that the open shell species serves as a planar transition state for enantiomerization of <b>CHTE</b> with an estimated activation energy of ∼20 kcal/mol. …”

Table2_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.XLSX by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

Addition of ARPP-21 into the signaling network confers input-order constraint. by Anu G. Nair (461390)

“…(E) The mean (solid black line) of normalized pSubstrate activation area and associated standard deviation (shaded grey region) produced by two fold increase or decrease in individual parameter values, one at a time. …”

Image1_Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers.JPEG by Roberto Martin-Hernandez (3661549)

“…Using an independent dataset, associations of the genes included in the signature with Overall Survival (OS) data demonstrated that patients with differential expression levels of 8 genes and 4 micro RNA's showed a statistically significant decrease in OS. We also found an independent prognostic signature for ACC with potential use in clinical practice, combining 9-gene/micro RNA features, that successfully predicted high-risk ACC cancer patients.…”

<i>trx</i> regulates <i>tan</i> expression and is involved in female abdominal pigmentation and its plasticity. by Jean-Michel Gibert (68707)

“…<i>trx</i> down-regulation induced a decrease in <i>tan</i> expression (t-test; *: p<0.05). …”

The Impacts of Human Disturbance on Species Abundance in Pond and Impermeable Habitats by Setareh Rezvani (3113955)

“…A woody plant is defined as a tree greater than 1.5 meters in height.…”