Table_1_Differential effects on TDP-43, piezo-2, tight-junction proteins in various brain regions following repetitive low-intensity blast overpressure.XLSX by Lanier Heyburn (7055039)

“…</p>Methods<p>In this study, using a rodent model of relBOP and western blotting for protein expression we showed the differential expression of various neuropathological proteins like TDP-43, tight junction proteins (claudin-5, occludin, and glial fibrillary acidic protein (GFAP)) and a mechanosensitive protein (piezo-2) in different regions of the brain at different intensities and frequency of blast.…”

Glycolysis is significantly upregulated in the PAH lung. by Yidan Zhao (522267)

“…Lung lysate (20 ug per lane) was loaded and immunoblotted with antibody against G6PC3 or LDHB and GAPDH (loading control). Consistent with a significant decrease of G6PC3 and an increase of LDHB gene expression in PAH, protein expression for G6PC3 (39KD) was significantly decreased while LDH (37KD) was significantly increased in PAH lungs compared with NL lungs. …”

Supplementary Material for: Meta-analysis of the efficacy and safety of finerenone in diabetic kidney disease by Zheng Y. (4132180)

“…Analysis results demonstrated that patients receiving finerenone showed a significant decrease in changing urinary albumin-to-creatinine ratio (UACR) from baseline (MD: ﹣0.30; 95%CI [﹣0.33, ﹣0.27] P=0.46, I2=0%) (P＜0.05). …”

10 μM βE2 pretreatment for 0.5 hrs protected primary cultured SD rat retinal cells from apoptosis induced by 100 μM H₂O₂ treatment for 24 hrs. by Yan Feng (128912)

“…<p>The PI3K/Akt pathway mediated this process, but the alteration in [Ca²⁺]_i was undetectable. A: The Annexin V/Propidium Iodide staining apoptosis assay; B: Quantitative data of A; C and D: Cell viability and [Ca²⁺]_i quantitative data; 10 μM βE2 pretreatment for 0.5 hrs significantly restored the decrease in cell viability and apoptosis, which was significantly inhibited by 10 μM LY (B, C), but the [Ca²⁺]_i was not significantly altered in all treated groups (D); E: Western blot results, 10 μM βE2 pretreatment for 0.5 hrs promoted p-Akt level, which was inhibited by 10 μM LY pretreatment for 0.5 hrs before βE2 and H₂O₂ co-treatment. …”

Table_4_miR-344-5p Modulates Cholesterol-Induced β-Cell Apoptosis and Dysfunction Through Regulating Caveolin-1 Expression.docx by Xulong Sun (11195769)

“…<p>Diabetes is a metabolic disorder induced by the modulation of insulin on glucose metabolism, and the dysfunction and decreased number of islets β-cells are the main causes of T2DM (type 2 diabetes mellitus). …”

Image_2_Metagenomic analysis demonstrates distinct changes in the gut microbiome of Kawasaki diseases children.pdf by Linli Han (19186516)

“…However, the molecular mechanisms of KD were not fully underlined, leading to a confused situation in disease management and providing precious prognosis prediction. …”

Image1_TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity.JPEG by Yun-Yi Li (12031955)

“…Through in vivo isopeptidase activity analysis by rescue expression of SENP1 and its Y270 mutants in a SENP1 CRISPR knockout T cell line, we found that SENP1 Y270F downregulated its isopeptidase activity towards both SUMO1 and SUMO2/3 conjugation by reducing SENP1 binding with sumoylated targets. …”

Table_1_White Matter Abnormalities of Auditory Neural Pathway in Sudden Sensorineural Hearing Loss Using Diffusion Spectrum Imaging: Different Findings From Tinnitus.DOCX by Zihao Zhang (2335846)

“…<p>Sudden sensorineural hearing loss (SSNHL) is a complex and challenging emergency which requires evidence regarding its pathophysiological changes to guide the treatment. …”

Image_5_Severe COVID-19 Is Associated With an Altered Upper Respiratory Tract Microbiome.jpeg by Meghan H. Shilts (5900660)

“…</p>Objective<p>Our primary objective was to identify URT microbiome signature/s that consistently changed over a spectrum of COVID-19 severity.</p>Methods<p>Using data from 103 adult participants from two cities in the United States, we compared the bacterial load and the URT microbiome between five groups: 20 asymptomatic SARS-CoV-2-negative participants, 27 participants with mild COVID-19, 28 participants with moderate COVID-19, 15 hospitalized patients with severe COVID-19, and 13 hospitalized patients in the ICU with very severe COVID-19.…”

Table_3_Conventional-Vincristine Sulfate vs. Modified Protocol of Vincristine Sulfate and L-Asparaginase in Canine Transmissible Venereal Tumor.DOCX by Chanokchon Setthawongsin (6568634)

“…<p>Background: Vincristine (VCR) is a mono-chemotherapy for canine transmissible venereal tumor (CTVT). …”

Table_5_Comparative Physiological and Transcriptome Profiles Uncover Salt Tolerance Mechanisms in Alfalfa.XLSX by Jiali Li (436886)

“…It was interesting to find that salinity caused a decrease in total unsaturated fatty acid in Adrenalin other than Magnum Salt, C18:2 was increased significantly after salinity in Magnum Salt, while it was unaltered in Adrenalin. …”

Developing Updateable Habitat Models for Endangered Stephens’ Kangaroo Rats Using Satellite ImageryPhase I - Rangewide Habitat Model by Heather Rusigian-Romsos (6093715)

“…The available data (10 and 20m spatial resolution, updated every five days, covering a wide electromagnetic spectrum) provide more nuanced and rapidly updateable information compared to more traditional geospatial datasets that are often too imprecise or too unreliably updated for useful habitat tracking.…”

Image_5_p53 Deacetylation Alleviates Sepsis-Induced Acute Kidney Injury by Promoting Autophagy.pdf by Maomao Sun (2427562)

“…After sepsis stimulation, the autophagy levels of RTECs increased temporarily, followed by a sharp decrease. Autophagy inhibition was accompanied by an increased renal tubular injury score. …”

DataSheet1_Nitrogen Fixation at the Edges of Boron Nitride Nanomaterials: Synergy of Doping.docx by Venkata Surya Kumar Choutipalli (4381336)

“…<p>Synthesis of ammonia at ambient conditions is very demanding yet challenging to achieve due to the production of ammonia fuel, which is considered to be a future fuel for sustainable energy. In this context, computational studies on the catalytic activity of the edge sites of boron nitride nanomaterials for possible nitrogen reduction into ammonia have been investigated. …”

Modulation of human monocytes by exposure to mitochondrial DNA. by Irene Fernández-Ruiz (5653951)

“…<p>(<b>A</b>) Workflow diagram: MΦs from HV were pre-exposed to mitochondrial DNA isolated from HeLa (mtDNA, 5 µg/ml, white bars), LPS (10 ng/ml, gray bars) or left untreated (black bars) for 5 days, then stimulated for 24 h with LPS, as described in the scheme. …”

Association between Serum Atypical Fibroblast Growth Factors 21 and 19 and Pediatric Nonalcoholic Fatty Liver Disease by Anna Alisi (139476)

“…FGF21 and FGF19 showed a tendency to decrease from CTRL (median FGF21 = 196 pg/mL; median FGF19 = 201 pg/mL) to NASH− (FGF21 = 89 pg/mL; FGF19 = 81 pg/mL) to NASH+ patients (FGF21 = 54 pg/mL; FGF19 = 41 pg/mL) (<i>p</i><0.001 for all comparisons) and were inversely associated with the probability of NASH and fibrosis in children with NAFLD. …”

DataSheet_3_Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis.csv by Wenjuan Qian (3909184)

“…<p>Temperature affects seed germination and seedling growth, which is a critical and complex stage in plant life cycle. …”

Data Sheet 1_An oral M-cell targeted Lactococcus lactis vaccine against Echinococcus multilocularis infection.pdf by Yang Xiao (146335)

“…For both primary and secondary infections, oral immunization with LL-plSAM-GILE led to a significant decrease in the diameter and weight of hepatic cysts.…”

Image 1_Therapeutic plasma exchange accelerates immune cell recovery in severe COVID-19.pdf by Aurelie Guironnet-Paquet (15407171)

“…</p>Methods<p>In this study, we set up a prospective, randomised clinical trial (ClinicalTrials.gov ID: NCT04751643) and performed therapeutic plasma exchange (TPE) in severe COVID-19 patients in order to decrease excess cytokines and auto-antibodies and to assess whether adding TPE to the standard treatment (ST, including corticosteroids plus high-flow rate oxygen) could help restore immune parameters and limit the progression of acute respiratory distress syndrome (ARDS).…”

Model performance evaluation results. by Ke Yan (331581)

“…On the other hand, taking English writing teaching as an example, the proposed method is further verified by designing a comparative experiment in groups. The results show that: (1) From the experimental data of word sense disambiguation, the accuracy of the SMOSS-LSTM model proposed in this paper is the lowest when the context range is "3+3", then it rises in turn at "5+5" and "7+7", reaches the highest at "7+7", and then begins to decrease at "10+10"; (2) Compared with the control group, the accuracy of syntactic analysis in the experimental group reached 89.5%, while that in the control group was only 73.2%. (3) In the aspect of English text error detection, the detection accuracy of the proposed model in the experimental group is as high as 94.8%, which is significantly better than the traditional SMOSS-based text error detection method, and its accuracy is only 68.3%. (4) Compared with other existing researches, although it is slightly inferior to Bidirectional Encoder Representations from Transformers (BERT) in word sense disambiguation, this proposed model performs well in syntactic analysis and English text error detection, and its comprehensive performance is excellent. …”