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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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144801
Table1_Curcumin-loaded graphene oxide quantum dots enhance otoprotective effects via blocking cuproptosis.docx
Published 2023“…</p><p>Conclusion: The results demonstrate that CUR/GOQDs is a promising therapeutic agent that can prevent CIS-induced ototoxicity by blocking the cuproptosis signal pathway.…”
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144802
Table 1_The role and mechanism of “eight famous herbals in Zhejiang” in cancer via network pharmacology and experimental validation.docx
Published 2024“…Finally, we found that three active ingredients (ferulic acid, luteolin, and quercetin) could inhibit the proliferation of NSCLC cells and decrease the protein expression of EGFR in a concentration-dependent manner. …”
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144803
Free energy properties in cultured neural networks.
Published 2015“…<p>Transitions during learning (left) and overall before-and-after changes (right) in connection strengths (top) and in three descriptors of evoked responses modeled on information-theoretic functions (bottom). <b>(A)</b> Connection strengths of the neural population estimated from the number of evoked response per trial. …”
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144804
Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number
Published 2016“…Hence, each tissue of an individual seems to regulate mtCN in a tissue-related rather than an individual-dependent manner. …”
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144805
Table_1_Zika Induces Human Placental Damage and Inflammation.docx
Published 2020“…An evaluation of BDNF showed a decrease that could modulate neuronal damage in the developing fetus. …”
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144806
Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response
Published 2015“…Our results provide a better understanding of the host response to WNV infection and highlight multiple targets for the development of antiviral and anti-inflammatory therapies.…”
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144807
Interplay between Active Chromatin Marks and RNA-Directed DNA Methylation in <i>Arabidopsis thaliana</i>
Published 2013“…We previously showed that <i>Arabidopsis thaliana</i> plants with mutations in the H3K4m2/m3 demethylase <i>JUMONJI 14</i> (<i>JMJ14</i>) exhibit a mild reduction in RNA-directed DNA methylation (RdDM) that is associated with an increase in H3K4m2/m3 levels. …”
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144808
Changes in Patch Features May Exacerbate or Compensate for the Effect of Habitat Loss on Forest Bird Populations
Published 2011“…<div><p>One and a half centuries after Darwin visited Chiloe Island, what he described as “…an island covered by one great forest…” has lost two-thirds of its forested areas. …”
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144809
Image_6_Metabolomics and Lipidomics Reveal the Effect of Hepatic Vps33b Deficiency on Bile Acids and Lipids Metabolism.JPEG
Published 2019“…In addition, lipid profiles were significantly altered with the lack of Vps33b in the liver. A variety of lipids, such as triglycerides and sphingomyelins, were significantly decreased in the liver and increased in the serum of hepatic Vps33b-depleted mice compared to those in wild-type mice. …”
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144810
Ethnic inequality impacts after 10 years from two sodium reduction interventions (CVD mortality rates, rate ratios and rate differences, and QALYs gained for individuals given mode...
Published 2015“…<p><sup><b>a</b></sup> CVD mortality rates in 2021, and rate differences in CVD mortality rates, per 100,000 population. …”
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144811
Lipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosis
Published 2015“…LPS can induce the formation of autophagosomes through a TLR4-dependent pathway, and LPS may exacerbate the apoptosis in AMs. …”
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144812
Synonymous Rare Arginine Codons and tRNA Abundance Affect Protein Production and Quality of TEV Protease Variant
Published 2014“…<div><p>It has been identified that a TEV protease (TEVp) variant, TEVp<sup>5M</sup>, displays improved solubility. …”
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144813
Image_1_Assessing the adaptive role of cannabidiol (CBD) in Cannabis sativa defense against cannabis aphids.jpeg
Published 2023“…In addition to cannabinoids, C. sativa also possesses a range of defense mechanisms via phytohormone signaling pathways that are well described in other plant species. …”
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144814
TNFα stabilizes myocardin mRNA through MEK/MAPK and NF-κB pathways.
Published 2014“…<p>(<b>A</b>) VSMCs were serum-starved for 24 h and transcription was blocked using α-amanitin (50 µM). …”
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144815
Differences in Fine-Root Biomass of Trees and Understory Vegetation among Stand Types in Subtropical Forests
Published 2015“…One examination compared two categories of basal areas (high vs. low basal area) in stands of single species. A second examination compared single-species and mixed stands with comparable basal areas. …”
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144816
Further Studies on the Latitudinal and Temporal Trends of Persistent Organic Pollutants in Norwegian and U.K. Background Air
Published 2004“…Data are presented for PBDEs, PCBs, and selected organochlorine compounds, measured at background locations by passive air samplers (semipermeable membrane devices, SPMDs) along a latitudinal transect from the south of the U.K. to the north of Norway during 2000−2002. …”
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144817
PDE1 inhibition reduces palmitate-induced apoptosis and stimulates CREB phosphorylation in INS-1 cells.
Published 2019“…<p>A) Incubation of INS-1 cells with palmitate for 12h significantly elevates caspase-3/7 activation (*, P < 0.05 compared to BSA; Student’s unpaired t-test). …”
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144818
DataSheet1_Improved the Activity of Phosphite Dehydrogenase and its Application in Plant Biotechnology.PDF
Published 2021“…<p>Phosphorus (P) is a nonrenewable resource, which is one of the major challenges for sustainable agriculture. …”
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144819
Table1_Exosomal circSCMH1/miR-874 ratio in serum to predict carotid and coronary plaque stability.doc
Published 2023“…ROC curve analysis demonstrated that lg (circSCMH1/miR-874) has a higher diagnostic value for ACS, AMI and medium-high risk plaques than previously used predictive ratios.…”
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144820
S-nitrosoglutathione inhibits pyroptosis of kidney tubular epithelial cells in sepsis via the SIRT3/SOD2/mtROS signaling pathway
Published 2025“…</p> <p>By constructing a mice model of sepsis, we pretreated them with SNG and used biochemical methods to detect the levels of serum inflammatory factors and mitochondrial reactive oxygen species (mtROS), assessed the severity of kidney injury and KTECs mitochondrial damage, and detected the expression of KTECs pyroptosis-related proteins and sirtuin 3 (SIRT3)/superoxide dismutase 2 (SOD2) pathway proteins.…”