An <i>in-silico</i> analysis to identify structural, functional and regulatory role of SNPs in <i>hMRE11</i> by Bhoomi Tarapara (11977197)

“…<p>Meiotic recombination 11 (<i>MRE11</i>) is a component of the tri-molecular <i>MRE11</i>-RAD50-NBS1 (MRN) complex, which functions as an exonuclease and endonuclease which is involved in identifying, signalling, protecting and repairing double-strand breaks in DNA (DSBs). …”

Oxidative stress and NF-κB signaling are involved in LPS induced pulmonary dysplasia in chick embryos by Yun Long (1421299)

“…Upon LPS exposure, pulmonary cell proliferation was significantly altered and cell apoptosis was inhibited as well, indicating a delayed progress of pulmonary development. LPS treatment also resulted in reduced CAV-1 expression and up-regulation of Collagen I, suggesting increased lung fibrosis, which was verified by Masson staining. …”

Preferential Ionic Interactions and Microscopic Structural Changes Drive Nonideality in Binary Ionic Liquid Mixtures as Revealed from Molecular Simulations by Utkarsh Kapoor (3396041)

“…Further, predictions of ionic conductivities using both the Nernst–Einstein formalism and Einstein relationship pointed to the presence of correlated ionic motion which was confirmed by the long ion-pair relaxation time constants especially for the anion present as a minor component.…”

Image_1_Association of Increased Circulating Acetic Acid With Poor Survival in Pseudomonas aeruginosa Ventilator-Associated Pneumonia Patients.tif by Xiaoling Qi (5564066)

“…</p>Results<p>We developed a partial least squares discriminant analysis (PLS-DA) model to examine differential SCFAs in 49 patients with PA-VAP. …”

Table_1_Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.DOCX by Masato Nishiwaki (666290)

“…However, B50, B100, and B200 caused a significant decrease in arterial stiffness for approximately 30–60 min: heart-brachial pulse wave velocity (B50: −4.5 ± 2.4%; B100: −3.4 ± 1.3%; B200: −8.1 ± 2.6%); brachial-ankle pulse wave velocity (B50: −0.6 ± 2.0%; B100: −3.3 ± 1.1%; B200: −9.3 ± 3.0%); heart-ankle pulse wave velocity (B50: −3.7 ± 0.3%; B100: −3.3 ± 0.9%; B200: −8.1 ± 2.7%); and cardio-ankle vascular index (B50: −4.6 ± 1.3%; B100: −5.6 ± 0.8%; B200: −10.3 ± 3.1%). …”

Image_1_NPV-BSK805, an Antineoplastic Jak2 Inhibitor Effective in Myeloproliferative Disorders, Causes Adiposity in Mice by Interfering With the Action of Leptin.PDF by Magalie Haissaguerre (5217461)

“…Our results provide evidence for a specific anabolic effect exerted by antineoplastic drugs targeting the Jak2 pathway, which is due to interference with the actions of leptin. …”

Table_1_Ethanol combined with energy drinks: Two decades of research in rodents.pdf by Beatriz Nunes Petribu (14703073)

“…Although the AmED group presented higher glucose levels than the EtOH group when drugs were administered by gavage, this was not observed in a self-administration protocol. AmED may induce higher kidney damage, higher levels of plasma urea, uric acid and creatinine when compared to EtOH. …”

Table_4_Modeling of the Potential Geographical Distribution of Three Fritillaria Species Under Climate Change.docx by Ruiping Jiang (11924855)

“…<p>Fritillaria species, a well-known Chinese traditional medicine for more than 2,000 years, have become rare resources due to excessive harvesting. …”

Evaluation of rheological models for concrete submitted to alkali-aggregate reaction based on numerical analysis of damping - free expansion by Marlon de Barros Cavalcanti (10449300)

“…Hence, long-term prediction is a problem still posing great challenge to engineers. …”

Data_Sheet_1_Evaluating the impact of loneliness and social isolation on health literacy and health-related factors in young adults.docx by Shradha Vasan (14512475)

“…Objectives<p>In current study, we aim to extend previous research by investigating the unique impact of loneliness on health literacy and health-related factors of young adults, after controlling for social isolation, depressive symptomology, and social anxiety, as well as evaluate how social isolation and loneliness differ in their impact on health literacy, and health-related factors among young adults, after accounting for abovementioned concomitant variables.</p>Methods<p>Using a cross-sectional study design, 521 young adults completed an online survey in 2020, where they self-reported their loneliness, social isolation, health-related factors, and health literacy data.…”

Sf-TPx1 knock-down caused significant increase in radiation-induced ROS generation and cell death. by Shashank Hambarde (386874)

“…<p>Sf9 cells were transfected with 1 µg siRNA against Sf-TPx1 with 6 µl RNAiFect transfection reagent and incubated for 24 h at 28°C. (A) Western immunoblot shows significant decrease in Sf-TPx1 level 24 h after siRNA transfection. …”

Variation in defensive traits against herbivores of native and invasive populations of <i>Carpobrotus edulis</i> by Jonatan Rodríguez (9852590)

“…To test this, we conducted a greenhouse experiment to compare morphological and physiological traits of <em>Carpobrotus edulis</em>, collected in its native (South Africa) and introduced (Chile and Spain) ranges, attacked by the generalist spittlebug <em>Philaenus spumarius</em> and the specialist scale insect <em>Pulvinariella mesembryanthemi</em>. …”

DataSheet1_Comparative study between apocynin and protocatechuic acid regarding antioxidant capacity and vascular effects.PDF by Murilo E. Graton (11668348)

Constriction rate variation produced by partial ligation of the portal vein at pre-hepatic portal hypertension induced in rats by Daren Athiê Boy RODRIGUES (10390476)

“…The calculation of the constriction rate was performed using a specific mathematical formula (1 - π r 2 / π R2) x 100% and the statistical analysis with the Student t test. …”

Table_3_Dose of Alcohol From Beer Required for Acute Reduction in Arterial Stiffness.DOCX by Masato Nishiwaki (666290)

“…However, B50, B100, and B200 caused a significant decrease in arterial stiffness for approximately 30–60 min: heart-brachial pulse wave velocity (B50: −4.5 ± 2.4%; B100: −3.4 ± 1.3%; B200: −8.1 ± 2.6%); brachial-ankle pulse wave velocity (B50: −0.6 ± 2.0%; B100: −3.3 ± 1.1%; B200: −9.3 ± 3.0%); heart-ankle pulse wave velocity (B50: −3.7 ± 0.3%; B100: −3.3 ± 0.9%; B200: −8.1 ± 2.7%); and cardio-ankle vascular index (B50: −4.6 ± 1.3%; B100: −5.6 ± 0.8%; B200: −10.3 ± 3.1%). …”

Image_1_Metabolic Profiling and Post-harvest Behavior of “Dottato” Fig (Ficus carica L.) Fruit Covered With an Edible Coating From O. ficus-indica.JPEG by Alessio Allegra (5719397)

“…Alanine, xylulose, aspartic acid, glutamic, acid and 2,5-dihydroxypyrazine showed a significant role on discriminating edible coated fruit from untreated ones. …”

Cytokines and chemokines in lung tissue after sham procedure or double hit (DH) in wild type (wt) mice (black bars) or in absence of C5 (C5^-/-) mice (grey bars). Systemi... by Miriam Kalbitz (3150195)

“…<p><b>A</b>. Increased IL-6 levels in lung tissue of wt and in C5^-/- mice after DH compared to sham. …”

Enhanced Selective CO₂ Capture upon Incorporation of Dimethylformamide in the Cobalt Metal–Organic Framework [Co₃(OH)₂(btca)₂] by Hai-Yun Ren (544398)

“…As society’s demand for energy increases and more CO₂ emissions are produced, it becomes imperative to selectively capture CO₂ and decrease the amount emitted to the atmosphere. Here, we present a flexible and porous metal–organic framework (MOF), [Co₃(OH)₂(btca)₂] (<b>1</b>) (where btca = benzotriazole-5-carboxylic acid), which exhibits excellent CO₂ uptake (223.7 mg g^–1 at 273 K and 104.7 mg g^–1 at 298 K) and better selectivity for CO₂/N₂ (46.3 at 273 K) . …”

DataSheet_1_IL-12α deficiency attenuates pressure overload-induced cardiac inflammation, hypertrophy, dysfunction, and heart failure progression.doc by Umesh Bhattarai (3875449)

“…Our results showed that IL-12α KO significantly ameliorated TAC-induced left ventricular (LV) failure, as evidenced by a smaller decrease of LV ejection fraction. IL-12α KO also exhibited significantly attenuated TAC-induced increase of LV weight, left atrial weight, lung weight, right ventricular weight, and the ratios of them in comparison to body weight or tibial length. …”

Table 1_Enhancement of prefrontal functional connectivity under the influence of concurrent physical load during mental tasks.docx by Shan Cheng (1569355)

“…</p>Discussion<p>From the perspective of prefrontal functional connectivity, this study supports measurable effects of physical factor on operators’ mental load. The results provide a reference for the real-time (or online) assessment of the MWL level in the natural environment.…”