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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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146401
image3_X-Ray Causes mRNA Transcripts Change to Enhance Orai2-Mediated Ca2+ Influx in Rat Brain Microvascular Endothelial Cells.tif
Published 2021“…Moreover, the change in SOCE was suppressed by btp-2, which is a non-selective inhibitor of Orai. Additionally, x-ray exposure induced a significant decrease of proliferation in BMECs in the dose- and time-dependent manner.…”
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146402
Diverse Aquatic Adaptations in <i>Nothosaurus</i> spp. (Sauropterygia)—Inferences from Humeral Histology and Microanatomy
Published 2016“…In the middle to late Anisian (Middle Muschelkalk) small-bodied nothosaurs retain BMI whereas larger-bodied forms tend to show a decrease in bone mass (BMD). During the latest Anisian to early Ladinian (Upper Muschelkalk), small- and few large-bodied nothosaurs retain BMI, whereas the majority of large-bodied forms exhibit BMD. …”
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146403
Image_3_Sirt3 Ameliorates Oxidative Stress and Mitochondrial Dysfunction After Intracerebral Hemorrhage in Diabetic Rats.TIF
Published 2018“…<p>Aim: Sirtuin3 (sirt3) plays a pivotal role in improving oxidative stress and mitochondrial dysfunction which directly induced neuronal apoptosis after intracerebral hemorrhage (ICH). …”
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146404
SAHA/TRAIL treatment induces apoptosis in uterine sarcoma cells involving the mitochondrial pathway.
Published 2014“…Mitochondrial depolarization in dead cells or cells undergoing apoptosis is indicated by a decrease in the red/green fluorescence intensity ratio. …”
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146405
DCC Receptor is Required Downstream of PKA for CB<sub>2</sub>R Induced Reorganization of the growth cone.
Published 2013“…Pharmacological modulation of the CB<sub>2</sub>R did not induce any significant changes in growth cone surface area nor filopodia number in primary neuron cultures obtained from <i>dcc</i><sup>−/−</sup> mice embryos (I and K) whereas JWH133 and JWH015 induced a decrease in growth cone surface and filopodia number while AM630 and JTE907 augmented these endpoints in <i>dcc</i><sup>+/+</sup> neuron cultures (J and L) (mean ± SEM; 125 to 219 per conditions, *P<0.05 vs control condition). …”
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146406
Table_2_Olfactory Dysfunction in Frontline Health Care Professionals During COVID-19 Pandemic in Brazil.pdf
Published 2021“…Since self-reported perception of smell is subjective and SARS-CoV-2 exposure is variable in the general population, we aimed to study a population that would be more homogeneously exposed to the virus. …”
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146407
Insights into the mechanism regulating the differential expression of the P28-OMP outer membrane proteins in obligatory intracellular pathogen <i>Ehrlichia chaffeensis</i>
Published 2021“…EcxR activated the <i>tr1</i> expression in response to a temperature decrease. At 37°C low level of Tr1 activated the <i>p28</i> expression. …”
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146408
DataSheet1_Clerodendranthus spicatus [Orthosiphon aristatus (Blume) Miq.] maintains uric acid homeostasis via regulating gut microbiota and restrains renal inflammation in hyperuri...
Published 2024“…In addition, C. spicatus modulated gut microbiota and decreased the relative abundance of Bacteroides, Prevotellaceae_UCG-001 and Alistipes, and increased the abundance of Alloprevotella and Lachnospiraceae_NK4A136_group.C.spicatus altered the expression of the renal urate transporter and key enzymes in hepatic urate synthesis, leading to a decrease in serum uric acid levels. …”
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146409
DataSheet_2_Single-cell mass cytometric analysis of peripheral immunity and multiplex plasma marker profiling of non-small cell lung cancer patients receiving PD-1 targeting immune...
Published 2023“…We showed the induction of CD69 and IL-2R on CD4+ CD25+ T-cells upon chemotherapy; the exhaustion of one CD8+ T-cell population was detected by the loss of CD127 and a decrease in CD27. CD19+CD20+, CD79B+, or activated B-cell subtypes showed CD69 increase and downregulation of BTLA, CD27, and IL-2R in NSCLC patients following chemotherapy or ICI.…”
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146410
Video_1_Underwater Sound Levels in Glacier Bay During Reduced Vessel Traffic Due to the COVID-19 Pandemic.avi
Published 2021“…Our results suggest that all types of vessels had a role in the quieter underwater sound environment in 2020, with the combined acoustic footprint of tour vessels and cruise ships most evident in the decrease in the 95th percentile loudest sounds. …”
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146411
Data_Sheet_1_Cytosolic Nudix Hydrolase 1 Is Involved in Geranyl β-Primeveroside Production in Tea.docx
Published 2022“…An antisense oligo-deoxynucleotide study confirmed that suppression of CsNUDX1-cyto transcription in tea shoots led to a significant decrease in geranyl β-primeveroside abundance. …”
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146412
Image_2_Changes in synaptic inputs to dI3 INs and MNs after complete transection in adult mice.tif
Published 2023“…Introduction<p>Spinal cord injury (SCI) is a debilitating condition that disrupts the communication between the brain and the spinal cord. …”
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146413
DataSheet_1_Protein Kinase CK1α Sustains B-Cell Receptor Signaling in Mantle Cell Lymphoma.pdf
Published 2021“…We also provided evidence that CK1α-mediated regulation of CARD11 and BTK likely implicates a physical interaction. The combination of CK1α inhibition with Ibrutinib or Duvelisib synergistically increased cytotoxicity, leading to a further decrease of the activation of BCR signaling pathways. …”
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146414
Sub-watersheds of the Gilgel Gibe catchment.
Published 2023“…The projected climate change shows a decrease in surface runoff, groundwater, and water yield, resulting in an overall decline of annual flow. …”
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146415
Magnetic Nanorobots as Maneuverable Immunoassay Probes for Automated and Efficient Enzyme Linked Immunosorbent Assay
Published 2022“…As a typical, classical, but powerful biochemical sensing technology in analytical chemistry, enzyme-linked immunosorbent assay (ELISA) shows excellence and wide practicability for quantifying analytes of ultralow concentration. …”
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146416
Table 1_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx
Published 2025“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”
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146417
Data_Sheet_2_Community-based treatment of cutaneous leishmaniasis using cryotherapy and miltefosine in Southwest Ethiopia: the way forward?.docx
Published 2023“…Background<p>Cutaneous leishmaniasis (CL) is a common, yet massively underreported skin morbidity in Ethiopia. …”
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146418
Table_2_Alterations of the gut virome in patients with systemic lupus erythematosus.xlsx
Published 2023“…</p>Results<p>SLE patients exhibited a significant decrease in gut viral diversity in the bulk metagenome dataset, but this change was not significant in the VLP metagenome dataset. …”
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146419
Image 2_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.jpg
Published 2025“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”
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146420
Table_5_Resveratrol Mediates the Apoptosis of Triple Negative Breast Cancer Cells by Reducing POLD1 Expression.xlsx
Published 2021“…<p>Resveratrol (RSV) is known to possess anticancer properties in many types of cancers like breast cancer, in which POLD1 may serve as a potential target. However, the anticancer mechanism of RSV on triple negative breast cancer (TNBC) remains unclear. …”