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greatest decrease » greater decrease (Expand Search), treatment decreased (Expand Search), greater increase (Expand Search)
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223541
Image_2_Polysaccharides From Chrysanthemum morifolium Ramat Ameliorate Colitis Rats via Regulation of the Metabolic Profiling and NF-κ B/TLR4 and IL-6/JAK2/STAT3 Signaling Pathways...
Published 2018“…Meanwhile, the elevated expression levels of pp65, TLR4, p-STAT3, and p-JAK2 were significantly decreased after treatment. Results suggested that CP would be a potential prebiotics for alleviation of TNBS-induced colitis. …”
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223542
Data Sheet 1_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.docx
Published 2025“…However, the specific effects of different drainage durations on soil microorganisms and metabolites remain unclear. This study adopted a multi-omics research method. After nontargeted metabolomics analysis of lipids as the main metabolite, microbial diversity analysis and lipidomics analysis were conducted to determine the main influencing factors. …”
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223543
Table_1_Physiological, Proteomic Analysis, and Calcium-Related Gene Expression Reveal Taxus wallichiana var. mairei Adaptability to Acid Rain Stress Under Various Calcium Levels.DO...
Published 2022“…Studies have shown that AR can leach calcium ions from plants and soil. Calcium (Ca) is also a crucial regulator of the plant stress response, whereas there are few reports on how Ca regulates the response of AR-resistant woody plants to AR stress. …”
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223544
Image_1_Relationship between gut microbiota and lymphocyte subsets in Chinese Han patients with spinal cord injury.TIF
Published 2022“…Therefore, it is possible to improve immune dysregulation in SCI patients by modulating gut microbiota, which may serve as a new therapeutic method for SCI.</p>…”
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223545
Hepatic injury and CA II expression and activity after cold ischemia and normothermic reperfusion.
Published 2015“…<p>(A) Hepatic injury measured as AST and ALT levels after 2h-normotermic <i>ex-vivo</i> perfusion. …”
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223546
Table_4_Carbon Amendments Influence Composition and Functional Capacities of Indigenous Soil Microbiomes.XLSX
Published 2020“…Mesocosms were established with soil from two field sites varying in soil organic matter content (low organic matter, LOM; high organic matter, HOM), that were amended at intervals over nine months with low or high dose solutions of glucose, fructose, malic acid, a mixture of these compounds, or water only (non-amended control). …”
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223547
Image_2_Calcium-Binding Protein S100P Promotes Tumor Progression but Enhances Chemosensitivity in Breast Cancer.JPEG
Published 2020“…</p>Conclusion<p>S100P promotes the aggressive properties of breast cancer cells and may be considered as a promising therapeutic target. Moreover, S100P can be used to predict the therapeutic effect of chemotherapy in HER2+ breast cancer patients.…”
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223548
Data_Sheet_4_E3 ligase RNF5 inhibits type I interferon response in herpes simplex virus keratitis through the STING/IRF3 signaling pathway.ZIP
Published 2022“…<p>Herpes simplex keratitis (HSK), caused by the herpes simplex virus 1 (HSV-1), is a major blinding disease in developed countries. …”
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223549
MCRs differentially regulate EPO-induced phosphorylation of ERK, STAT5 and AKT in erythroblasts during differentiation.
Published 2015“…<p><b>(A)</b> Phosphorylation of ERK, STAT and AKT in erythroblasts. …”
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223550
Table_1_Determination of the effective dose of dexmedetomidine to achieve loss of consciousness during anesthesia induction.DOCX
Published 2023“…Background<p>Dexmedetomidine (DEX) is a sedative with greater preservation of cognitive function, reduced respiratory depression, and improved patient arousability. …”
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223551
Image_2_Residual OXPHOS is required to drive primary and metastatic lung tumours in an orthotopic breast cancer model.tif
Published 2024“…Background<p>Fast adaptation of glycolytic and mitochondrial energy pathways to changes in the tumour microenvironment is a hallmark of cancer. Purely glycolytic ρ<sup>0</sup> tumour cells do not form primary tumours unless they acquire healthy mitochondria from their micro-environment. …”
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223552
Protein signatures in serum and urine in three murine urothelial cancer models.
Published 2021“…Significantly altered serum proteins in (A) MB49 orthotopic model (n = 6), (B) Carcinogen induced female C57BL/6 mice (n = 6), (C) 10-week endpoint Hgf-Cdk4<sup>R24C</sup> mice (n = 13), (D) MIBC endpoint Hgf-Cdk4<sup>R24C</sup> mice (n = 8) compared to respective healthy controls (n = 6–10). …”
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223553
Image_2_ATF3 Suppresses Growth and Metastasis of Clear Cell Renal Cell Carcinoma by Deactivating EGFR/AKT/GSK3β/β-Catenin Signaling Pathway.TIFF
Published 2021“…The potential mechanism affected by ATF3 was analyzed through gene set enrichment analysis (GSEA) and verified using western blotting, invasion assay, or immunofluorescence staining. Furthermore, a xenograft mouse model was used to assess the function of ATF3 in vivo.…”
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223554
Supplementary Material for: <b><i>NT5C2</i></b> Gene Polymorphisms and the Risk of Coronary Heart Disease
Published 2020“…<b><i>Background:</i></b> Increasing studies have reported that 5′-nucleotidase cytosolic II (<i>NT5C2</i>) has a strong relationship with coronary heart disease (CHD) development. …”
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223555
Image_1_The Interaction Mechanism Between Herpes Simplex Virus 1 Glycoprotein D and Host Antiviral Protein Viperin.jpg
Published 2019“…<p>Viperin is an interferon-inducible protein that responsible for a variety of antiviral responses to different viruses. …”
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223556
Data_Sheet_1_Cytosolic Glucose-6-Phosphate Dehydrogenase Is Involved in Seed Germination and Root Growth Under Salinity in Arabidopsis.pdf
Published 2019“…Compared to wild type, the mutant seeds showed a reduced germination rate and root elongation under salt stress. …”
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223557
Data_Sheet_1_Peri-interventional Triple Therapy With Dabigatran Improves Vasomotion and Promotes Endothelialization in Porcine Coronary Stenting Model.docx
Published 2021“…<p>Objective: We evaluated the short and long-term effect of peri-interventional dabigatran therapy on vasomotion, endothelialization, and neointimal formation in a porcine coronary artery stenting model.</p><p>Background: Stenting of coronary arteries induces local inflammation, impairs vasomotion and delays endothelialization.…”
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223558
Image_3_Hypoxia-Inducible Factor 1α and 2α Have Beneficial Effects in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Aged Rats.TIF
Published 2020“…ACF also reversed the activation of the Akt signaling pathway induced by RIPC following stroke. HIF may play a key role in RIPC, which was likely mediated by the Akt signaling pathway and systemic modulation of the inflammatory response in aged rats.…”
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223559
Image_1_Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model.jpg
Published 2023“…Male ICR mice were randomly divided into 3 groups: mice fed with a low-fat diet (LFD group); mice fed with very high fat diet (VHFD group), and mice fed with VHFD supplemented with THC (300 mg/kg/day orally) (VHFD+THC treated group) for 6 weeks. …”
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223560
Results of the D-H panel causality test.
Published 2024“…Conversely, renewable energy consumption (REC) is an element that can increase economic activity and therefore decline the environmental damages to secure a green economy. Likewise, the growth in cases of Covid-19 also reduces the usage of resources like land, water, and forests and subsequently decreases carbon emissions, promoting the green economy. …”