CB2R negatively regulates NLRP3 inflammasome activation in peritoneal macrophages stimulated with LPS/DSS. by Ping Ke (3110763)

“…The expression of NLRP3, Casp-1 p20/Casp-1 p45 ratio, proIL-1β and IL-1β mRNA were analyzed. (A and B) Pre-incubated with HU 308 significantly decreased the expressions of NLRP3, Casp-1 p20/Casp-1 p45 ratio, proIL-1β and IL-1β mRNA. n = 6 per group. …”

Image_6_Physio-biochemical and transcriptomic analysis of Bacillus amyloliquefaciens PG-4-induced salt stress tolerance in Macrotyloma uniflorum.JPEG by Yanna Wu (7675676)

“…</p>Results<p>In presence of different salt levels, PG-4 showed a high potentiality to produce several plant growth promoting metabolites such as NH₃, siderophore, 1-aminocyclopropane-1-carboxylic acid deaminase (ACC-deaminase), and hydrolytic enzymes. …”

Molecular Control of Innate Immune Response to <i>Pseudomonas aeruginosa</i> Infection by Intestinal <i>let-7</i> in <i>Caenorhabditis elegans</i> by Lingtong Zhi (3137130)

“…<i>aeruginosa</i> PA14 infection, SDZ-24 was identified as a direct target for intestinal <i>let-7</i>. SDZ-24 was found to be predominantly expressed in the intestine, and <i>P</i>. …”

Image_1_Long-Term Functional and Cytoarchitectonic Effects of the Systemic Administration of the Histamine H1 Receptor Antagonist/Inverse Agonist Chlorpheniramine During Gestation... by Rocío Valle-Bautista (9386582)

“…The qRT-PCR analysis revealed a reduction in the expression of Satb2 and FoxP2. …”

The effect and mechanism of miR-30e-5p targeting SNAI1 to regulate epithelial-mesenchymal transition on pancreatic cancer by Ziyu Liang (8844584)

“…Subsequently, PCa cells were transfected with a vector overexpressing SNAI1 (OE-SNAI1) and miR-30e-5p mimics, miR-30e-5p inhibitors, or empty vectors. …”

Video_3_Murine Metatarsus Bone and Joint Collagen-I Fiber Morphologies and Networks Studied With SHG Multiphoton Imaging.AVI by Martin Vielreicher (10957656)

“…Multiphoton Second Harmonic Generation (SHG) microscopy, is able to visualize the sterical topology of the collagen-I fibrillar network in 3D, in a minimally invasive and label-free manner. Penetration depths exceed those of conventional visible light imaging and can be further optimized through employing decalcification or optical clearing processing ex vivo. …”

Differentially used transcripts (DUT) for T1R and LEP groups suggest dysregulation of inflammatory circuitry in T1R. by Wilian Correa-Macedo (11813183)

“…Gene symbols in red case present examples discussed in the main text, while bold letters indicate transcripts displaying a usage switch. PΔ = difference of transcript proportion between the stimulated vs non-stimulated cells by group.…”

Image_2_Metagenome Analysis of Intestinal Bacteria in Healthy People, Patients With Inflammatory Bowel Disease and Colorectal Cancer.tif by Yongshun Ma (9737837)

“…Objectives<p>Several reports suggesting that the intestinal microbiome plays a key role in the development of inflammatory bowel disease (IBD) or colorectal cancer (CRC), but the changes of intestinal bacteria in healthy people, patients with IBD and CRC are not fully explained. …”

Single Nucleotide Polymorphisms of the Angiotensin-Converting Enzyme (<i>ACE)</i> Gene Are Associated with Essential Hypertension and Increased ACE Enzyme Levels in Mexican Individ... by Nancy Martínez-Rodríguez (417462)

“…</p><p>Results</p><p>Under a dominant model, rs4291 rs4335, rs4344, rs4353, rs4362, and rs4363 polymorphisms were associated with an increased risk of hypertension after adjusting for age, gender, BMI, triglycerides, alcohol consumption, and smoking. …”

Percutaneous kyphoplasty for osteoporotic vertebral compression fractures improves spino-pelvic alignment and global sagittal balance maximally in the thoracolumbar region by Zhong Cao (1437541)

“…Percutaneous kyphoplasty (PKP) is a common method for the treatment of local kyphosis. …”

Image8_Interleukin 9 mediates T follicular helper cell activation to promote antibody responses.jpeg by Taiki Sato (394623)

“…Accumulating evidence indicates a crucial role for interleukin-9 (IL-9) in the formation of germinal centers (GCs), enhancing the generation of class-switched high-affinity antibodies. …”

Image_2_Metagenome Analysis of Intestinal Bacteria in Healthy People, Patients With Inflammatory Bowel Disease and Colorectal Cancer.tif by Yongshun Ma (9737837)

“…Objectives<p>Several reports suggesting that the intestinal microbiome plays a key role in the development of inflammatory bowel disease (IBD) or colorectal cancer (CRC), but the changes of intestinal bacteria in healthy people, patients with IBD and CRC are not fully explained. …”

Table_1_Physio-biochemical and transcriptomic analysis of Bacillus amyloliquefaciens PG-4-induced salt stress tolerance in Macrotyloma uniflorum.DOCX by Yanna Wu (7675676)

“…</p>Results<p>In presence of different salt levels, PG-4 showed a high potentiality to produce several plant growth promoting metabolites such as NH₃, siderophore, 1-aminocyclopropane-1-carboxylic acid deaminase (ACC-deaminase), and hydrolytic enzymes. …”

E1AF involved in the mouse FAK gene transcription activation in B16F1 cells. by Shufeng Li (48761)

“…<p>(A) Activation of FAK promoter by ETS transcription factor E1AF. …”

Image_2_Vaginal Lactobacilli Induce Differentiation of Monocytic Precursors Toward Langerhans-like Cells: in Vitro Evidence.TIF by Jie Song (60883)

“…Finally, the recognized receptors of L. crispatus (such as TLR2 and TLR6) and the upstream transcription factors (PU.1, TAL1, TIF1γ, and POLR2A) of CD207 were examined, and the expression of these molecules was enhanced in THP-1 cells following L. crispatus treatment. …”

The Interaction of LFA-1 on Mononuclear Cells and ICAM-1 on Tubular Epithelial Cells Accelerates TGF-β1-Induced Renal Epithelial-Mesenchymal Transition by Yoshiyuki Morishita (210781)

“…Although the migration and invasion of HK-2 cells induced full EMT by a high dose (10.0 ng/ml) and long-term (72–96 hrs) TGF-β₁ stimulation increased, that of HK-2-TGF-β₁ (0.1)-PBMCs did not increase. …”

Cyclic Tetrathiophenes Planarized by Silicon and Sulfur Bridges Bearing Antiaromatic Cyclooctatetraene Core: Syntheses, Structures, and Properties by Takeshi Ohmae (1934089)

“…In comparison of the ¹H NMR chemical shifts of <b>1</b>−<b>3</b> with those of the corresponding precursors, upfield shifts due to a paratropic ring current in the COT ring were observed and the degree of shift increased with increasing planarity of the COT ring. …”

GSC induces EMT but not collective cell migration of HCC cells. by Tong-Chun Xue (533132)

“…<p>(A) Ectopic expression of GSC in Hep3B cells induced changes in expression of EMT markers, particularly E-cadherin. …”

Top 10 up- and downregulated genes. by Shi-Qi Yao (13976253)

“…</p><p>Conclusions</p><p>This study, for the first time, delineated the gene expression changes following ON injury in embryonic and neonatal mice, providing a new resource of age- and injury-driven data on axonal growth capacity.…”

Image_4_Comprehensive evaluation of the mechanism of Gastrodia elata Blume in ameliorating cerebral ischemia–reperfusion injury based on integrating fecal metabonomics and 16S rDNA... by Ximeng Ding (14018481)

“…The present study has shown a significant effect of G. elata Blume in improving cerebral ischemia–reperfusion injury (CIRI). …”