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greatest decrease » greater decrease (Expand Search), treatment decreased (Expand Search), greater increase (Expand Search)
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9941
Primary Microcephaly Gene <em>MCPH1</em> Shows Signatures of Tumor Suppressors and Is Regulated by miR-27a in Oral Squamous Cell Carcinoma
Published 2013“…MCPH1 has also been shown to be downregulated in breast, prostate and ovarian cancers, and mutated in 1/10 breast and 5/41 endometrial tumors, suggesting that it could also function as a tumor suppressor (TS) gene. To test the possibility of <i>MCPH1</i> as a TS gene, we first performed LOH study in a panel of 81 matched normal oral tissues and oral squamous cell carcinoma (OSCC) samples, and observed that 14/71 (19.72%) informative samples showed LOH, a hallmark of TS genes. …”
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9942
Presentation_1_Comparative analysis of the biological characteristics and mechanisms of azole resistance of clinical Aspergillus fumigatus strains.pdf
Published 2023“…<p>Aspergillus fumigatus is a common causative pathogen of aspergillosis. At present, triazole resistance of A. fumigatus poses an important challenge to human health globally. …”
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9943
Q76A and F80A substitutions in Vpx disrupt ability of SIVmac 239 to transduce macrophages.
Published 2008“…<p>(A) Q76A and F80A substituted Vpx are efficiently incorporated into SIVmac virions. …”
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9944
Epstein-Barr Virus-Encoded LMP2A Induces an Epithelial–Mesenchymal Transition and Increases the Number of Side Population Stem-like Cancer Cells in Nasopharyngeal Carcinoma
Published 2010“…Finally, we demonstrate that Akt inhibitor (V) greatly decreases the size of the stem cell side populations in LMP2A-expressing cells. …”
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9945
Effect of high-intensity interval training on glycemic control in adults with type 1 diabetes with overweight or obesity: a randomized controlled trial with partial cross-over
Published 2020“…</p> <p> </p> <p><b>Results:</b> Participants were aged 44±10 years, with diabetes duration 19±11 years, and BMI 30.1±3.1 kg/m<sup>2</sup>.<sup> </sup>HbA1c decreased from 8.63 ± 0.66% at baseline to 8.10 ± 1.04% at 12 weeks in the HIIT intervention group (p=0.01), however this change was not significantly different to the control group (HIIT -0.53 ± 0.61%, control -0.14 ± 0.48%, p=0.08). …”
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9946
Table_1_Opposite Profiles of Complement in Antiphospholipid Syndrome (APS) and Systemic Lupus Erythematosus (SLE) Among Patients With Antiphospholipid Antibodies (aPL).pdf
Published 2019“…We observed significantly (a) higher protein levels of total C4, C4A, C4B, C3, and anticardiolipin (ACLA) IgG, (b) increased frequencies of lupus anticoagulant and males, and (c) decreased levels of complement factor H, MBL and ACLA-IgM among patients with thrombosis than those without thrombosis (N = 288). …”
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9947
Table_1_Association of rs2910164 in miR-146a with type 2 diabetes mellitus: A case–control and meta-analysis study.xlsx
Published 2022“…Subgroup analysis showed that, compared with the CC genotype, CG + GG genotype was associated with a decreased risk of T2DM in the subgroup of individuals ≥ 65 years old (OR = 0.75; 95% CI: 0.58–0.98; P<sub>adjusted</sub> = 0.032) and BMI < 18.5 (OR = 0.16; 95% CI: 0.03–0.89; P<sub>adjusted</sub> = 0.037). …”
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9948
Table 1_Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort.docx
Published 2025“…Objective<p>To compare the real-world clinical efficacy and safety of interleukin (IL)-17A inhibitors (secukinumab [SEC] and ixekizumab [IXE]) versus the IL-23 inhibitor guselkumab (GUS) in patients with nail psoriasis, with a focus on site-specific biologic therapeutic responses (nail matrix vs. nail bed) in a 24-week prospective observational cohort.…”
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9949
Protective effects on the retina after ranibizumab treatment in an ischemia model - Fig 4
Published 2017“…</b> Also, in both groups fewer ChAT<sup>+</sup> cells were visible (p<0.001). <b>C.</b> A significant decrease of <i>ChAT</i> mRNA was noted in the ischemia (p = 0.017) as well as in the ranibizumab groups (p = 0.014). …”
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9950
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9951
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9952
Long-Term Endurance Exercise in Humans Stimulates Cell Fusion of Myoblasts along with Fusogenic Endogenous Retroviral Genes <i>In Vivo</i>
Published 2015“…Comparing muscle biopsies from post- with the pre-competitive seasons a significant 2.25-fold increase of myonuclei/mm fiber, a 2.38-fold decrease of fiber area/nucleus and a 3.1-fold decrease of satellite cells (SCs) occurred. …”
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9953
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9954
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9955
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9956
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9957
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9958
Physical performance parameters of rock samples.
Published 2024“…The ringing counts and b-values of sandstone displayed an approximate "W" shape distribution, with a subsequent decrease in b-values during final failure. …”
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9959
MTS-816 and acoustic emission monitoring system.
Published 2024“…The ringing counts and b-values of sandstone displayed an approximate "W" shape distribution, with a subsequent decrease in b-values during final failure. …”
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9960