Annotation of Allosteric Compounds to Enhance Bioactivity Modeling for Class A GPCRs by Lindsey Burggraaff (6243110)

“…Endogenous ligands, such as hormones and neurotransmitters, bind to the orthosteric site, while synthetic ligands may bind to orthosteric or allosteric sites, which has become a focal point in drug discovery. Usually, such allosteric modulators bind to a protein noncompetitively with its endogenous ligand or substrate. …”

Cas9 and LOF allele behavior in a 3 population model. by Georg Oberhofer (3401438)

Annotation of Allosteric Compounds to Enhance Bioactivity Modeling for Class A GPCRs by Lindsey Burggraaff (6243110)

“…Endogenous ligands, such as hormones and neurotransmitters, bind to the orthosteric site, while synthetic ligands may bind to orthosteric or allosteric sites, which has become a focal point in drug discovery. Usually, such allosteric modulators bind to a protein noncompetitively with its endogenous ligand or substrate. …”

Proposed cutoff values for men in a very high risk region. by Gleb E. Svinin (18397739)

Sub-lethal concentrations of neonicotinoid insecticides at the field level affect negatively honey yield: Evidence from a 6-year survey of Greek apiaries by Robert G. Chambers (6635327)

“…Based on production function estimates, we found that sub-lethal concentrations of two widely used neonicotinoid insecticides (imidacloprid and thiamethoxam) detected in the nectar of flowers resulted in substantial losses in honey production for commercial beekeepers in our sample. By simulating a scenario with ideal pathogenic and environmental conditions, we found that the magnitude of the neonicotinoid effects decreases significantly under ideal conditions providing evidence for possible synergies at the field between neonicotinoids and environmental and pathogenic factors. …”

Children’s Quality of Life Based on the KIDSCREEN-27: Child Self-Report, Parent Ratings and Child-Parent Agreement in a Swedish Random Population Sample by Anne H. Berman (615685)

“…<div><p>Background</p><p>The KIDSCREEN-27 is a measure of child and adolescent quality of life (QoL), with excellent psychometric properties, available in child-report and parent-rating versions in 38 languages. …”

Tryptophan quenching of LtxA by KI. by Angela C. Brown (1343826)

“…When LtxA is incubated with membranes, regardless of the lipid composition, K_SV decreases to 0.4, indicating 40% accessibility of the residues. *, p < 0.05; ***, p < 0.005.…”

Image_1_A GMC Oxidoreductase GmcA Is Required for Symbiotic Nitrogen Fixation in Rhizobium leguminosarum bv. viciae.TIF by Qian Zou (8612823)

“…The mutation in gmcA did not affect the growth of R. leguminosarum, but it displayed decreased antioxidative capacity at H₂O₂ conditions higher than 5 mM. …”

Image_1_A GMC Oxidoreductase GmcA Is Required for Symbiotic Nitrogen Fixation in Rhizobium leguminosarum bv. viciae.TIF by Qian Zou (8612823)

“…The mutation in gmcA did not affect the growth of R. leguminosarum, but it displayed decreased antioxidative capacity at H₂O₂ conditions higher than 5 mM. …”

Image_2_A GMC Oxidoreductase GmcA Is Required for Symbiotic Nitrogen Fixation in Rhizobium leguminosarum bv. viciae.TIF by Qian Zou (8612823)

“…The mutation in gmcA did not affect the growth of R. leguminosarum, but it displayed decreased antioxidative capacity at H₂O₂ conditions higher than 5 mM. …”

Image_2_A GMC Oxidoreductase GmcA Is Required for Symbiotic Nitrogen Fixation in Rhizobium leguminosarum bv. viciae.TIF by Qian Zou (8612823)

“…The mutation in gmcA did not affect the growth of R. leguminosarum, but it displayed decreased antioxidative capacity at H₂O₂ conditions higher than 5 mM. …”

3D culture raw data by Yaojun Luo (20296512)

“…The decreased levels of IGF2BPs may influence the m⁶A modification of critical genes within the Hippo signaling pathway, thereby facilitating eWAT preadipocytes adipogenesis. …”

Data_Sheet_1_Combined Effects of Microplastics and Benzo[a]pyrene on the Marine Diatom Chaetoceros muelleri.docx by Yuanyuan Su (1474528)

“…<p>Microplastics are regarded as ubiquitous pollutants in the ocean and have attracted worldwide concerns. Benzo[a]pyrene (B[a]P), one of typical polycyclic aromatic hydrocarbons (PAHs), is commonly detected in marine environment. …”

DataSheet1_Assessing susceptibility for polycyclic aromatic hydrocarbon toxicity in an in vitro 3D respiratory model for asthma.PDF by Reese M. Valdez (18408114)

“…In this study, primary human bronchial epithelial cells (HBEC) cultured in 3D at the air-liquid interface (ALI) are utilized as a physiologically relevant model to evaluate the effects of inflammation on toxicity of polycyclic aromatic hydrocarbons (PAHs), a class of contaminants generated from incomplete combustion of fossil fuels. …”

<b>Beneficial Effects of Control-IQ Automated Insulin Delivery in Basal-Bolus and Basal-Only Insulin Users With Type 2 Diabetes</b> by Carol J. Levy (15369802)

Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…In the ocean hadal zone (below 6000 m), snailfish from the Kermadec (Yancey et al. 2014) and Mariana trenches (Linley et al. 2016), and several amphipod species including <i>Hirondellea gigas</i> (Downing et al. 2018), confirmed a highly linear trend in TMAO contents down to the greatest ocean depths at which these animals have been found (< 8,400 m for fish, ~11,000 m for amphipods). …”

Refractive error, spectacle wear, and referrals among public and private school children based on the AAPOS 2021 referral criteria. by Zahi Wehbi (14863016)

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Comparison of the amino acid sequence in DENV-2. by You-Yuan Tsai (3142086)

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Bayesian evolutionary analysis of DENV-1 isolated from a patient in 2015 in Tainan, Taiwan. by You-Yuan Tsai (3142086)

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Comparison of virus fitness of variant rgC-A314G (K73R) and WT. by You-Yuan Tsai (3142086)

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