Supplementary Material for: Two Years with COVID-19: The Electronic Frailty Index Identifies High-Risk Patients in the Stockholm GeroCovid Study by Mak J.K.L. (14195471)

“…<b><i>Introduction:</i></b> Frailty, a measure of biological aging, has been linked to worse COVID-19 outcomes. …”

Admission Blood Glucose Level and Its Association With Cardiovascular and Renal Complications in Patients Hospitalized With COVID-19 by Tom Norris (7380536)

“…Accounting for confounders, for all complications except cardiac ischaemia and stroke there was a non-linear association between glucose and cardiovascular and renal complications. …”

Table 1_Integrating comprehensive geriatric assessment into routine nursing care for older adults with type 2 diabetes: implementation fidelity and clinical outcomes.docx by Qinqin Sun (2942049)

“…Implementation fidelity was assessed using five validated dimensions yielding a composite score (mean 0.64, SD 0.19; range 0.28–0.94). …”

Functional and misfolded NTS1 during purification. by Jim F. White (361948)

“…This decrease of the amount of functional NTS1 is indicated by a left pointing arrow. …”

Model of cdr2 action in mitosis. by Kevin J. O'Donovan (250670)

“…<p>Cdr2 levels increase in G2, peak in mitosis and decrease as cells exit mitosis. Nuclear envelope breakdown in prometaphase allows newly synthesized cdr2 access to c-myc protein, which, like other transcription factors <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010045#pone.0010045-Delcuve1" target="_blank">[61]</a>, partitions itself off DNA during chromatin condensation, coinciding with mitotic shutdown of transcription. …”

Morphometric analysis. by Dalal G. Al-Adwani (8190696)

“…<b>D:</b> The crush group displays a significant decrease in nerve fiber diameter at both time points assessed following nerve injury compared with sham and naive groups. …”

Reinforcement of polyacrylamide-co-tert-butyl acrylate base gel using nanosilica for conformance control at low and high reservoir temperatures by Shamlooh M.

“…Silica (silicon dioxide) has been found to have a strengthening effect as well as it enhances the thermal and mechanical stability of the system. …”
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DataSheet1_Computational recognition of regulator genes and signature for ferroptosis with implications on immunological properties and clinical management of atopic dermatitis.pdf by Lei Xu (78676)

“…Finally, in vitro and in vivo models showed a notable FerrSig decrease in patients with AD versus healthy control. …”

Effect of vector control. by Temesgen Debas Awoke (18291050)

“…Moreover, applying a maximum of 15% additional effort to reduce the number of vectors, decreases the total VL prevalence by 57.71%. …”

Table_3_Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.xlsx by Ling Tong (632992)

“…In the cell experiment, forskolin (an adenylate cyclase activator) and zardaverine (a PDE4 inhibitor) enhance the cAMP pathway and decrease PD-L1 expression, while SQ2253 (an adenylate cyclase inhibitor) inhibits the cAMP pathway and increases PD-L1 expression of the LUAD cell lines H1299 and A549, and MYC regulation by these drugs was positively correlated with PD-L1 regulation, which verified the regulation of the cAMP/PDE4 pathway on MYC and PD-L1.…”

Table_3_Lyme borreliosis in pregnancy and associations with parent and offspring health outcomes: An international cross-sectional survey.PDF by Katherine Leavey (697697)

“…Background<p>Lyme disease (LD) is a complex tick-borne pathology caused by Borrelia burgdorferi sensu lato bacteria. …”

Table_1_Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.docx by Ling Tong (632992)

“…In the cell experiment, forskolin (an adenylate cyclase activator) and zardaverine (a PDE4 inhibitor) enhance the cAMP pathway and decrease PD-L1 expression, while SQ2253 (an adenylate cyclase inhibitor) inhibits the cAMP pathway and increases PD-L1 expression of the LUAD cell lines H1299 and A549, and MYC regulation by these drugs was positively correlated with PD-L1 regulation, which verified the regulation of the cAMP/PDE4 pathway on MYC and PD-L1.…”

Smad1 target genes repressed and activated in senescence. by Atsushi Kaneda (198186)

“…Genes were listed in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002359#pgen.1002359.s019" target="_blank">Table S5</a>. 581 genes with no increase of H3K27me3 reads (not shown), or 156 genes showing decrease of H3K27me3 reads by 0.4 or more (↓<i>column</i>), were significantly enriched upward (P = 0.01, and ^†P = 0.004, respectively), i.e. upregulated. …”

DataSheet_1_Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant... by Ju Zeng (3426107)

“…<p>Aging is a natural biological process associated with cognitive decline and neuroendocrine–immune system changes; the neuroendocrine–immune system plays crucial role in brain aging and neurodegeneration, and it is essential to discern beneficial attempts to delay the aging progress based on immunological aging. …”

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

“…Density functional theory calculations revealed a decrease in the computed OER overpotential on both Co and Fe sites of La_0.5Sr_0.5Fe_<i>x</i>Co_1–<i>x</i>O₃ (001) with increasing Co doping, where <i>x</i> = 0.25 was found to be the most active, hence validating the observed trend and demonstrating the validity of the setup for screening the entire composition space simultaneously.…”

Table_2_ACC deaminase-producing endophytic fungal consortia promotes drought stress tolerance in M.oleifera by mitigating ethylene and H2O2.docx by Bushra Rehman (14292428)

“…The co-inoculum (TP+TR) also induced the antioxidant potential and enzyme activities POX (325%), CAT activity (166%), and AsA (21%), along with a lesser decrease (-2%) in water potential in M. oleifera plants with co-inoculation under water deficit compared with non-inoculated control. …”

Rapamycin-independent <i>IGF2</i> expression in <i>Tsc2</i>-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells by Blanca E. Himes (153105)

“…<div><p>Lymphangioleiomyomatosis (LAM) is a rare, almost exclusively female lung disease linked to inactivating mutations in <i>tuberous sclerosis complex 2</i> (<i>TSC2)</i>, a tumor suppressor gene that controls cell metabolic state and growth via regulation of the mechanistic target of rapamycin (mTORC1) signaling. mTORC1 is frequently activated in human cancers and, although the mTORC1 inhibitor rapamycin has a cytostatic effect, it is, in general, unable to elicit a robust curative effect or tumor regression. …”

Table_1_Parasitemia and Associated Immune Response in Pregnant and Non-Pregnant Beef Cows Naturally Infected With Neospora caninum.docx by Ignacio Gual (12871562)

“…This correlates with higher antibody levels and a decrease in total leukocyte counting. The precise timing of the parasitemia may be used for diagnosis purposes and/or for design strategies to avoid vertical transmission. …”

DataSheet_1_Omicron SARS-CoV-2 infection management and outcomes in patients with hematologic disease and recipients of cell therapy.docx by José Luis Piñana (12514534)

“…</p>Purpose<p>To assess the current clinical management and outcome of SARS-CoV-2 infection diagnosed, identify the risk factors for severe outcomes according to the HD characteristics and cell therapy procedures in a real-world setting.</p>Methods<p>A retrospective observational registry led by the Spanish Transplant Group (GETH-TC) with 692 consecutive patients with HD from December 2021 to May 2023 was analyzed.…”

Theory and X‑ray Absorption Spectroscopy for Aluminum Coordination Complexes – Al K‑Edge Studies of Charge and Bonding in (BDI)Al, (BDI)AlR₂, and (BDI)AlX₂ Co... by Alison B. Altman (1664254)

“…These trends suggested that the higher transition energies observed for (BDI)­AlX₂ systems with more electronegative X^1– ligands could be ascribed to a decrease in electron density around the aluminum atom, which causes an increase in the attractive potential of the Al nucleus and concomitant increase in the binding energy of the Al 1s core orbitals. …”