Image_11_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

“…Although the cytokine release by CD19.CAR-T cells upon activation was not hampered by both COX-inhibitors, activation and proliferation of CAR-T cells were significantly inhibited via diminishing the NF-ĸB signaling pathway by a significant down-regulation of expression of CD27 on CD4⁺ and CD8⁺ CAR-T cells, followed by a clear decrease of phosphorylated NF-ĸB p65 in both CD4⁺ and CD8⁺ CAR-T cells by a factor of 1.8. …”

Image_2_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

“…Although the cytokine release by CD19.CAR-T cells upon activation was not hampered by both COX-inhibitors, activation and proliferation of CAR-T cells were significantly inhibited via diminishing the NF-ĸB signaling pathway by a significant down-regulation of expression of CD27 on CD4⁺ and CD8⁺ CAR-T cells, followed by a clear decrease of phosphorylated NF-ĸB p65 in both CD4⁺ and CD8⁺ CAR-T cells by a factor of 1.8. …”

Image_8_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

“…Although the cytokine release by CD19.CAR-T cells upon activation was not hampered by both COX-inhibitors, activation and proliferation of CAR-T cells were significantly inhibited via diminishing the NF-ĸB signaling pathway by a significant down-regulation of expression of CD27 on CD4⁺ and CD8⁺ CAR-T cells, followed by a clear decrease of phosphorylated NF-ĸB p65 in both CD4⁺ and CD8⁺ CAR-T cells by a factor of 1.8. …”

Image_6_Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy.tif by Mingya Yang (1655299)

“…Although the cytokine release by CD19.CAR-T cells upon activation was not hampered by both COX-inhibitors, activation and proliferation of CAR-T cells were significantly inhibited via diminishing the NF-ĸB signaling pathway by a significant down-regulation of expression of CD27 on CD4⁺ and CD8⁺ CAR-T cells, followed by a clear decrease of phosphorylated NF-ĸB p65 in both CD4⁺ and CD8⁺ CAR-T cells by a factor of 1.8. …”

Heterogeneous Diplomacy of Political Relations between Iran and Afghanistan in exploiting the water of Helmand Border River by Poorhashemi, Abbas

“…Due to growing water consumption by upstream countries of the border rivers in exploiting the resources, we will observe an increase in hydro-political disputes among the nations. Helmand is a river that flows into Iran and includes a hydro-political aspect. …”
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Table_2_Plant Factories Are Heating Up: Hunting for the Best Combination of Light Intensity, Air Temperature and Root-Zone Temperature in Lettuce Production.docx by Laura Carotti (10044914)

“…The photon conversion efficiency (both dry and fresh weight) decreased with increasing photon flux: 29, 27, and 21 g FW shoot and 1.01, 0.87, and 0.76 g DW shoot per mol incident light at 200, 400, and 750 μmol m^–2 s^–1, respectively, averaged over all temperature combinations, following a concurrent decrease in specific leaf area (SLA). …”

Presentation 1_The global burden of neonatal sepsis attributable to air pollution from 1990 to 2021: findings from the global burden of disease study 2021.zip by Jiajia Duan (9351878)

“…</p>Result<p>In 2021, global deaths from neonatal sepsis and related infections attributable to air pollution numbered 54,026 (95% UI: 45,371–64,084), a 23.48% decrease from 1990, with age-standardized death rates dropping 1.49% annually (EAPC = −1.49). …”

DataSheet_1_Low fish meal diet supplemented with probiotics ameliorates intestinal barrier and immunological function of Macrobrachium rosenbergii via the targeted modulation of gu... by Xiaochuan Zheng (8450286)

“…Results showed that CPC substitution induced a significant decrease in digestive enzyme activities (trypsin and lipase) and gut barrier protein PT-1 expression and a significant increase in γ-GT enzyme activity and inflammatory-related factors (Relish and Toll) expression. …”

Reduced Expression of miR-200 Family Members Contributes to Antiestrogen Resistance in LY2 Human Breast Cancer Cells by Tissa T. Manavalan (406097)

“…One hallmark of tumor progression is epithelial-to-mesenchymal transition (EMT), characterized by a loss of cell adhesion resulting from reduced E-cadherin and increased cell mobility. miR-200 family members regulate EMT by suppressing expression of transcriptional repressors ZEB1/2. …”

Rational Molecular Design of Phenanthroimidazole-Based Fluorescent Materials toward High-Efficiency Deep-Blue OLEDs by Molecular Isomer Engineering by Yaxue Wang (19676389)

“…However, deep-blue OLEDs based on nondoped emitting layers with a satisfactory external quantum efficiency (EQE) are still rare for applications. …”

Association of objectively measured physical fitness during pregnancy with maternal and neonatal outcomes. The GESTAFIT Project by Laura Baena-García (8463066)

“…</p><p>Conclusion</p><p>Increasing physical fitness during pregnancy may promote better neonatal outcomes and is associated with a decrease in the risk of caesarean section.</p><p>This trial was registered at ClinicalTrials.gov (<a href="https://clinicaltrials.gov/ct2/show/NCT02582567" target="_blank">NCT02582567</a>) on October 20, 2015.…”

Structure Characterization and Properties of K‑Containing Copper Hexacyanoferrate by Dickson O. Ojwang (2814841)

“…Infrared, Raman, and Mössbauer spectroscopy studies show that Fe^III is continuously reduced to Fe^II with increasing <i>x</i>, accompanied by a decrease of the <i>a</i>-axis of the cubic <i>Fm</i>3̅<i>m</i> unit cell. …”

Image8_Mitomycin-Treated Endothelial and Smooth Muscle Cells Suitable for Safe Tissue Engineering Approaches.TIF by Irina Zakharova (766005)

“…During in vitro experiments, we have shown that treatment with mitomycin C does not lead to a decrease in cell viability. Despite the absence of proliferation, mitomycin C-treated vascular cells retain specific cell markers, produce specific extracellular matrix, and demonstrate the ability to stimulate angiogenesis in vivo. …”

Image4_Combined effect of traditional Chinese herbal-based formulations Jing Si herbal tea and Jing Si nasal drop inhibits adhesion and transmission of SARS-CoV2 in diabetic SKH-1... by Chien-Yi Chiang (344057)

“…The results showed that both JHT and JND were effective in alleviating the viral entry and accumulation in the thorax and the abdominal area. While JHT showed a dose-dependent decrease in the viral load, JND showed early inhibition of viral entry from day 1 of the infection. …”

Data_Sheet_1_Phenotypes and Baseline Risk Factors of Acute Kidney Injury in Children After Allogeneic Hematopoietic Stem Cell Transplantation.docx by Justinas Daraskevicius (9307817)

“…<p>Background: Acute kidney injury (AKI) is a frequent and widely recognized complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). …”

Table1_Mitomycin-Treated Endothelial and Smooth Muscle Cells Suitable for Safe Tissue Engineering Approaches.XLSX by Irina Zakharova (766005)

“…During in vitro experiments, we have shown that treatment with mitomycin C does not lead to a decrease in cell viability. Despite the absence of proliferation, mitomycin C-treated vascular cells retain specific cell markers, produce specific extracellular matrix, and demonstrate the ability to stimulate angiogenesis in vivo. …”

<i>rhlAB</i> promoter activity during different phases of growth in nutrient limitation batch culture. by Kerry E. Boyle (759216)

“…<p>GFP and promoter activity data are from the same growth curves shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004279#pcbi.1004279.g002" target="_blank">Fig 2</a>. …”

Image_1_Plant Factories Are Heating Up: Hunting for the Best Combination of Light Intensity, Air Temperature and Root-Zone Temperature in Lettuce Production.eps by Laura Carotti (10044914)

“…The photon conversion efficiency (both dry and fresh weight) decreased with increasing photon flux: 29, 27, and 21 g FW shoot and 1.01, 0.87, and 0.76 g DW shoot per mol incident light at 200, 400, and 750 μmol m^–2 s^–1, respectively, averaged over all temperature combinations, following a concurrent decrease in specific leaf area (SLA). …”

Image_2_Maternal Protein Restriction in Two Successive Generations Impairs Mitochondrial Electron Coupling in the Progeny’s Brainstem of Wistar Rats From Both Sexes.TIF by David F. Santana (6457592)

“…However, F2R-LP offspring, exposed to LP in the diets of the two preceding generations displayed a RS overproduction with a concomitant decrease in mitochondrial bioenergetics. …”

Rational Molecular Design of Phenanthroimidazole-Based Fluorescent Materials toward High-Efficiency Deep-Blue OLEDs by Molecular Isomer Engineering by Yaxue Wang (19676389)

“…However, deep-blue OLEDs based on nondoped emitting layers with a satisfactory external quantum efficiency (EQE) are still rare for applications. …”