Effectiveness of the 23-Valent Pneumococcal Polysaccharide Vaccine (PPV23) against Pneumococcal Disease in the Elderly: Systematic Review and Meta-Analysis by Gerhard Falkenhorst (278492)

“…</p><p>Conclusions</p><p>Our meta-analysis revealed significant VE of PPV23 against both IPD and pneumococcal pneumonia <i>by any serotype</i> in the elderly, comparable to the efficacy of PCV13 against <i>vaccine-serotype</i> disease in a recent clinical trial in elderly people. Due to its broader serotype coverage and the decrease of PCV13 serotypes among adults resulting from routine infant immunization with PCV13, PPV23 continues to play an important role for protecting adults against IPD and pneumococcal pneumonia.…”

Data Sheet 5_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.csv by Wentong Li (492392)

“…</p>Conclusion<p>This study elucidates the HSP90AA1-HSPA1B-DNAJB1 network as a key driver of VaD pathogenesis through dual mechanisms of protein homeostasis and immune reprogramming. …”

Data Sheet 1_Aleurone supplementation enhances the metabolic benefits of training in Standardbred mares: impacts on glucose-insulin dynamics and gut microbiome composition.pdf by Berit Boshuizen (3747655)

“…FSIGTT results also showed a decrease in logAIRg (P = 0.044). Training with Aleurone: Aleurone supplementation further reduced FSIGTT AIRg (P = 0.030), logAIRg (P = 0.021) while increasing glucose effectiveness (Sg; P = 0.031). …”

Table_4_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…Background<p>Systemic hypoperfusion plays a pivotal role in the pathogenesis of primary open-angle glaucoma (POAG). …”

Image_1_Relationship of iodine excess with thyroid function in 6-year-old children living in an iodine-replete area.tif by Yun Jeong Lee (7305383)

“…Excess iodine was associated with a decrease in FT4 or T3 levels and an increase in TSH levels. …”

Table_3_Progression of functional and structural glaucomatous damage in relation to diurnal and nocturnal dips in mean arterial pressure.doc by Jesus D. Melgarejo (11358747)

“…Background<p>Systemic hypoperfusion plays a pivotal role in the pathogenesis of primary open-angle glaucoma (POAG). …”

Datasheet2_Effectiveness of an online mental health strengthening module to build resilience and overcome stress for transitional aged medical students.pdf by Fransiska Kaligis (11685118)

“…Additionally, compared to the control group, there were significant increases in knowledge [F(1, 103) = 66.805, P < .001], attitudes and behavior towards mental-health [F(1, 103) = 5.191, P = .025], and a significant decrease in stress perception score [F(1, 103) = 27.567, P < .001]. …”

Image_6_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

DataSheet_1_Elevated inflammatory fecal immune factors in men who have sex with men with HIV associate with microbiome composition and gut barrier function.pdf by Katherine M. Littlefield (12647420)

“…</p>Results<p>Both MSM cohorts with HIV had elevated levels of fecal calprotectin, a clinically relevant marker of GI inflammation, and nine inflammatory fecal sIFs (GM-CSF, ICAM-1, IL-1β, IL-12/23, IL-15, IL-16, TNF-β, VCAM-1, and VEGF). …”

Adhesion of Als5 to collagen type IV involves recognition of carbohydrate residues on collagen type IV but is not solely determined by it. by Mohammad Faiz Ahmad (172608)

“…<p>(A) Adhesion of GST-Als5, GST-Als5-SS to collagen type IV. …”

Blunted rhythms in spontaneous firing in cells^LHb→DRN of susceptible mice. by He Liu (67509)

“…<p><b>(A)</b> Experimental timeline of viral surgeries to label cells^LHb-DRN, CSDS, SI test, and in vitro slice electrophysiology. …”

DataSheet1.DOCX by Alexander H. Turaihi (4995452)

“…</p><p>Results: IRS2^−/− RA exhibited normal vasomotor function, yet a decreased maximal diameter compared to IRS2^+/+ RA. …”

S1 Data - by Zahra Moradi Rekabdar Kalaiee (18823899)

“…</p><p>Results</p><p>The results showed that out of the 86 participating patients, 52 (60.5%) were male and 34 (39.5%), with a mean (Standard Deviation) of 39.14 (10.89) years old. …”

Table_2_Tandem mass tag labeled quantitative proteomic analysis of differential protein expression on total alkaloid of Aconitum flavum Hand.-Mazz. against melophagus ovinus.DOCX by Xinjian Wang (711385)

“…<p>Melophagus ovinus disease is a common ectoparasitosis, which can lead to a decrease in animal production performance, product quality, and even death. …”

DataSheet_1_Identification and validation of cuproptosis-related genes in acetaminophen-induced liver injury using bioinformatics analysis and machine learning.docx by Zhenya Guo (6188954)

“…Consistent with expectations, both mRNA and protein levels of the four OFGs exhibited a substantial decrease. The administration of ATTAM effectively mitigates copper elevation induced by APAP in both mouse model and AML12 cells. …”

Image2_NVP-BEZ235 Inhibits Renal Cell Carcinoma by Targeting TAK1 and PI3K/Akt/mTOR Pathways.JPEG by Bihui Li (11924447)

“…Likewise, in vivo, treatment with NVP-BEZ235 and PP242 suppressed the growth of xenografts generated from 786-0 and A498 cells, along with decreased expression of phospho-TAK1, phospho-c-Jun, and phospho-IκB-α. …”

Image_4_Photosynthetic Carbon Fixation and Sucrose Metabolism Supplemented by Weighted Gene Co-expression Network Analysis in Response to Water Stress in Rice With Overlapping Grow... by Xinpeng Wang (4611307)

“…However, ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) activity significantly decreased, resulting in a significant decrease in photosynthetic rate. …”

DataSheet1.pdf by Robert Šket (4666972)

“…<p>We explored the metagenomic, metabolomic and trace metal makeup of intestinal microbiota and environment in healthy male participants during the run-in (5 day) and the following three 21-day interventions: normoxic bedrest (NBR), hypoxic bedrest (HBR) and hypoxic ambulation (HAmb) which were carried out within a controlled laboratory environment (circadian rhythm, fluid and dietary intakes, microbial bioburden, oxygen level, exercise). …”

The Effect of SERCA1b Silencing on the Differentiation and Calcium Homeostasis of C2C12 Skeletal Muscle Cells by Adrienn Tóth (727269)

“…These changes were also accompanied by a reduced activity of CaN in cells with decreased SERCA1b. …”

DataSheet4_Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental V... by Qing Liu (20889)

“…</p><p>Results: In total, 63 chemical compounds from ELZC and 365 putative ARHL-related targets were identified, and 1860 ARHL-related targets were collected from the OMIM and GeneCards. A total of 145 shared targets of ELZC and ARHL were acquired by Venn diagram analysis. …”