Image 2_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif by Shaolian Zang (11987905)

“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”

Image 1_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif by Shaolian Zang (11987905)

“…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …”

Table_1_Glucose and Fatty Acid Metabolism of Dairy Cows in a Total Mixed Ration or Pasture-Based System During Lactation.DOCX by Mercedes García-Roche (6459200)

“…The peroxisome proliferator-activated receptor alpha (PPARA) mRNA was increased during early lactation (P < 0.05), and was positively associated to PPARGC1A, carnitine palmitoyl-transferase 1, and hydroxymethylglutaryl-CoA synthase 2 (HMGCS2) mRNA expression. …”

TKI clears α-Synuclein and protects TH⁺ neurons in a parkin-dependent manner. by Irina Lonskaya (429729)

Quarantine effectiveness, defined as the percentage of quarantined individuals that develop an infection, as a function of the probability of infection given a contact (<i>α</i>). by Maria M. Martignoni (8563158)

DataSheet1_Histamine H2 receptor antagonist exhibited comparable all-cause mortality-decreasing effect as β-blockers in critically ill patients with heart failure: a cohort study.ZIP by Xue-Sha Zhang (17379385)

“…Propensity score matching (PSM) was used to increase comparability of four groups.</p><p>Results: A total of 5593 patients were included. After PSM, multivariate analyses showed that patients in H2RAs group had close all-cause mortality with patients in β-blockers group. …”

(A) ELISA analysis of 1α-hydroxylase expression showing no significant changes in PTEC cells exposed to FGF-23 or Klotho alone but greatly decreased levels when exposed to both FGF-23 and Klotho by Damian Medici (88375)

CDF and Curcumin decreased clonogenicity and invasion in AsPC-1, AsPC1-GTR, MIAPaCa-2, and MIAPaCa-2-GTR cells. Clonogenic assay (A) Invasion assay (B). by Bin Bao (294271)

Checklist S1 - High-Dose Statin Pretreatment Decreases Periprocedural Myocardial Infarction and Cardiovascular Events in Patients Undergoing Elective Percutaneous Coronary Intervention: A Meta-Analysis of Twenty-Four Randomized Controlled Trials by Le Wang (165105)

Omeprazole decreases IL-4-stimulated eotaxin-3 protein secretion in primary esophageal squamous cells from two patients with EoE, (A) EoE1 and (B) EoE2. by Xi Zhang (83736)

Differences between substance users and non-users showing increases (red) and decreases (blue) in resting state functional connectivity in substance users displayed from an axial view on the left and a sagittal view on the right. by Alyssia Wilson (10987388)

The solubility of P^S129-α-synuclein but not P^S87-α-synuclein species is decreased in the brains of end-stage symptomatic hA30Pα-syn mice. by Margot Fournier (260993)

Image_2_Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio.JPEG by Maria Papathanou (5696720)

PKCη phosphorylated occludin from decreased Na^<b>+</b>/K^<b>+</b>-ATPase activity is a mechanism for noise-induced blood-labyrinth barrier disruption. by Yue Yang (52715)

“…G, Immunoblots for occludin from NE mice pre-treated with PKCηNC and PKCηPS. H, A 2.4-fold decrease in the (α/β) ratio occurred with PKCηPS pre-treatment (*P = 0.022<0.05). …”

Increased severity of colitis and decreased colonic lengths in P90 mice fed by a synthetic diet [low cellulose (2.5%, LC) as fiber] compared to regular chow (12.5% dietary fiber). by Dorottya Nagy-Szakal (378382)

The cell family heterogeneity metrics computed based on the AKT pathway for the CRC dataset samples showed a decreasing trend with increasing cancer stage (1 to 3) and tumor grade (G1 to G3). by John F. Graf (414116)

Ru360 in a dose-dependent manner (Ru360 dose-1 = 120 µg/Kg; dose-2 = 240 µg/Kg), decreased the resting state spontaneous electrical activity in the somatosensory cortex. by Basavaraju G. Sanganahalli (408881)

Regional cerebral increases (yellow blobs) and decreases (blue blobs) in Kleine-Levin patients (n = 4) during symptomatic episodes as compared to baseline asymptomatic period, superimposed on a template T1-weighted MRI. by Yves Dauvilliers (213843)

DataSheet_1_Adaptive Thermogenesis Driving Catch-Up Fat Is Associated With Increased Muscle Type 3 and Decreased Hepatic Type 1 Iodothyronine Deiodinase Activities: A Functional and Proteomic Study.xlsx by Celia Di Munno (10230458)

“…In parallel, liver D1 activity decreased during caloric restriction, and persisted during catch-up fat at a time-point when circulating levels of T4, T3 and rT3 were all restored to those of controls. …”

siRNA silencing of PhLP3 promotes MAPK phosphorylation upstream of RhoA activation and PhLP3 overexpression decreases levels of phosphorylated MAPK in suspension CHO LB01 cells. by Nandini V. L. Hayes (192607)

“…<p>(A) PhLP3 silenced LB01 cells were fixed and co-stained with either anti-MAPK (second panel, green) and rhodamine phalloidin (for filamentous actin, red) or anti-phosphorylated MAPK (fourth panel, green) and rhodamine phalloidin. …”