Retinal morphology and function is damaged in TALEN <i>clcc1</i>-KO zebrafish. by Lin Li (28817)

“…<i>clcc1</i> KO embryos show destruction of the rod photoreceptor layer (b) compared with WT (a). While somewhat better preserved than in the morpholino <i>clcc1</i> knockdown embryos, cone photoreceptors and the other retinal layers also appear decreased. …”

Effects of KU-55933 and metformin on metabolism in MCF-7 cells. by Mahvash Zakikhani (118421)

“…Loss of mitochondrial membrane potential (ΔΨ) is indicated by a decrease in FL2/FL1 fluorescence intensity ratio <b>(see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049513#pone.0049513.s001" target="_blank">Figure S1</a> for flow cytometry data set)</b>. …”

Fhl1b is essential for regulating the cell fate choice of liver versus pancreas and for β-cell regeneration. by Jin Xu (31283)

“…Decreased Fhl1b function leads to an increase in levels of <i>pdx1</i> expression in lateral 1 and 2 cells, causing a hepatic and pancreatic exocrine to a pancreatic endocrine fate switch. …”

Biomechanical effects of the abductor hip muscles local fatigue by Márcio Goethel (8995541)

“…When the volunteer failed to repeat the movements, the maximal voluntary isometric contraction of hip abduction was immediately tested using an isokinetic dynamometer Biodex System 4^®, in order to verify if there was a decrease of at least 50% in torque peak. Once fatigue observed, the volunteer was conducted to perform the tasks of squatting or drop landing, with no relevant resting period. …”

Expression of the ETS-5 target gene <i>gcy-9</i> restores CO₂-chemosensitivity to <i>ets-5</i> mutants. by Julia P. Brandt (176082)

“…Wild-type URX neurons (top panel) showed a small decrease in the ratio of YFP:CFP emissions in response to 10 s CO₂ pulses indicating decreases in cell calcium. …”

Monitoring intracellular K⁺ concentrations with GINKO2 in <i>E</i>. <i>coli</i> grown in K⁺-depleted media. by Sheng-Yi Wu (10887927)

“…<p>(A) <i>E</i>. <i>coli</i> are capable of accumulating K⁺ to a higher concentration than the environment. …”

Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia. by Krisztina Tóth (12009827)

“…<p><b>(A)</b> NKCC1 mRNA expression levels in newborn and adult microglia isolated from C57BL/6J mice compared to neural progenitors derived from E17 embryonic hippocampi. …”

FIGURE 5 from Proteasome Inhibition Reprograms Chromatin Landscape in Breast Cancer by H. Karimi Kinyamu (18387319)

“…Each row corresponds to a DOCR, and they are split by increase (<b>GAIN</b>) or decrease (<b>LOST</b>) in accessibility and by genomic category (<b>PROMOTER</b>, <b>GENIC</b>, <b>INTERGENIC</b>). …”

Combined Theoretical and Experimental Analysis of the Bonding in the Heterobimetallic Cubane-Type Mo₃NiS₄ and Mo₃CuS₄ Core Clusters by Juan Andrés (2440429)

“…However, the reductive addition of nickel into [Mo₃S₄(dmpe)₃Cl₃]⁺ causes a small decrease in the Mo 3d binding energies. …”

Macrophage phagolysosome inhibits reactivation despite containing reactivation-promoting factors. by Raffael Júnio Araújo de Castro (3875755)

“…<i>neoformans</i> H99O VBNC cells corroborate the findings of a previous report [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011841#ppat.1011841.ref014" target="_blank">14</a>], which indicates that 12.5 nM PA is the lowest concentration of PA required to decrease latency in VBNC cells. …”

Tonic nM DA stabilizes the timing of LP activity over the short term. by Wulf-Dieter C. Krenz (693267)

“…Note that absolute values were chosen because in some cases a given parameter could increase or decrease over time according to the preparation, so averaging did not reflect the degree of change that was observed.…”

Application of single step genomic BLUP under different uncertain paternity scenarios using simulated data by Rafael Lara Tonussi (4476496)

“…<div><p>The objective of this study was to investigate the application of BLUP and single step genomic BLUP (ssGBLUP) models in different scenarios of paternity uncertainty with different strategies of scaling the G matrix to match the A22 matrix, using simulated data for beef cattle. …”

The senescence-dependent spatial reorganization of H3K9me3-marked chromatin differs at the perinucleolar space and the nuclear periphery. by Stefan Dillinger (4063552)

“…<p>(<b>A</b>) Semi-quantitative immunoblots show severely decreased H3K9me3 and Lamin B1 levels, less strongly decreased H3 levels and no detectable alterations in Lamin A/C, tubulin and GAPDH levels in senescence. …”

Synaptotoxic PrP^Sc species are propagated from early in the evolution of M1000 prion disease. by Simote Totauhelotu Foliaki (5614364)

“…<p>(A) CA1 region LTP of WT mouse hippocampal slices was significantly disrupted following a five minute exposure to 0.5% (w/v; in artificial CSF) crude M1000 brain homogenates (cM1000) derived from M1000 infected WT Balb/c mice (infected through routine intracerebral injection [R.ic]) at 30% of the incubation period to the terminal stage of disease (TSD). …”

Supporting data for "Excess mortality during the COVID-19 pandemic in Hong Kong and South Korea" by Shuqi Xu (12992556)

“…Mortality from influenza and pneumonia was estimated to have a statistically significant increase in HK but a decrease in SK probability due to different coding practices. …”

Synthesis, Structure, and Properties of Low-Spin Manganese(III)−Poly(pyrazolyl)borate Complexes by Ferdaus Hossain (8659224)

“…The close conformity of mean Mn−N distances of 1.974(4), 1.984(5), and 1.996(4) Å in <b>1</b>, <b>2</b>, and <b>3</b>, respectively, indicates absence of the characteristic Jahn−Teller distortion of a high-spin d⁴ center. …”

BPLF1 regulates the expression and activity of TOP2 in productively infected LCLs. by Jinlin Li (2267896)

“…<p>The productive virus cycle was induced by treatment with 1.5 μg/ml Dox in LCL cells carrying recombinant EBV encoding wild type or catalytic mutant BPLF1 and a tetracycline regulated BZLF1 transactivator. …”

Hypoxia upregulates ALKBH5 <i>via</i> HIF-1α. by Armin Thalhammer (233088)

“…<p>(<b>A</b>) Hypoxic induction of <i>ALKBH1-8</i> in MCF7, U2OS and IMR32 cells. …”

Data_Sheet_1_Examining the diet quality of Canadian adults and the alignment of Canadian front-of-pack labelling regulations with other front-of-pack labelling systems and dietary... by Jennifer J. Lee (1843426)

“…Moving from the “least healthy” to the “most healthy” quintile in the CAN-FOPL dietary index system, intakes of protein, fiber, vitamin A, vitamin C, and potassium increased, while intakes of energy, saturated fat, total and free sugars, and sodium decreased. …”

Data_Sheet_1_Examining the diet quality of Canadian adults and the alignment of Canadian front-of-pack labelling regulations with other front-of-pack labelling systems and dietary... by Jennifer J. Lee (1843426)

“…Moving from the “least healthy” to the “most healthy” quintile in the CAN-FOPL dietary index system, intakes of protein, fiber, vitamin A, vitamin C, and potassium increased, while intakes of energy, saturated fat, total and free sugars, and sodium decreased. …”