image_5_Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells.PDF by Kornelis S. M. van der Geest (478975)

“…In addition, aging was associated with a decrease of nonclassic T helper 1 cells, as indicated by decreased percentages of CD161-expressing cells within the IFN-γ⁺ CD4⁺ T cell compartment of old subjects. …”

Effects of various parameters in spreading of cooperative behavior. by Sourav Roy (389598)

“…<p>Subfigure (a) reveals two contrasting scenarios, where the cooperators decrease with the increment of the mutation rate <i>μ</i>. …”

Differential genome-wide distribution of epigenetic markers between HCV infected vs. non-infected cells and its integration with gene expression. by Shira Perez (6857819)

“…<p>(A) Change in genome-wide distribution of epigenetic marks following HCV infection (100% HCV infected Huh7.5 cells, generated as described in the <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008181#sec010" target="_blank">Methods</a>) determined by ChIP-seq experiments, as well as change in gene expression determined by RNA-seq experiment. …”

FBW7 is degraded during <i>E</i>. <i>chaffeensis</i> infection. by Jennifer Y. Wang (8787527)

“…<p><b>A.</b> Confocal immunofluorescent microscopy was performed to observe colocalization of TRP120 (green) with FBW7 (red) and the temporal changes in FBW7 levels during <i>E</i>. …”

DataSheet_1_Upregulation of microRNA-125b-5p alleviates acute liver failure by regulating the Keap1/Nrf2/HO-1 pathway.docx by Ya-Chao Tao (11129590)

“…Meanwhile, LPS/D-GalN-challenged mice and Huh7 cells both showed decreased miR-125b-5p levels when compared to their untreated control group, suggesting that miR-125b-5p may have a protective role against liver injury, regardless of ACLF or ALF. …”

Workflow of the study. by Yasir Ali (799969)

“…<div><p>Interleukin-17F (IL-17F), considered a pro-inflammatory cytokine, has been shown to contribute to skeletal tissue degradation and hence chronic inflammation in rheumatoid arthritis (RA). …”

Distinct aging profiles of CD8⁺ T cells in blood versus gastrointestinal mucosal compartments by Jeffrey Dock (4386412)

“…By contrast, the only age-effect seen in the gut was a significant increase in CD45RA^- (memory) and concurrent decrease in CD45RA⁺CD28⁺ (naïve) CD8⁺ T cells. …”

Bioinformatic analyses of <i>IL-17F</i> gene. by Yasir Ali (799969)

“…<div><p>Interleukin-17F (IL-17F), considered a pro-inflammatory cytokine, has been shown to contribute to skeletal tissue degradation and hence chronic inflammation in rheumatoid arthritis (RA). …”

Data and metadata supporting the published article: Contralateral breast cancer risk in patients with ductal carcinoma in situ and invasive breast cancer by Daniele Giardiello (9401482)

“…Several studies have shown a decrease in CBC incidence as a result of (neo)adjuvant systemic therapies. …”

Patient characteristic. by Biniyam Tedla Mamo (20598461)

“…<div><p>Background</p><p>Neonatal sepsis is a leading cause of mortality and morbidity. To improve the clinical outcomes of neonates with sepsis, treatment should be based on bacteriological identification and antibiotic susceptibility. …”

Use of Fixed Dose Combination (FDC) Drugs in India: Central Regulatory Approval and Sales of FDCs Containing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Metformin, or Psychotro... by Patricia McGettigan (203640)

“…</p><p>Methods and Findings</p><p>This was an ecologic study with a time-trend analysis of FDC sales volumes (2007–2012) and a cross-sectional examination of 2011–2012 data to establish the numbers of formulations on the market with and without a record of CDSCO approval (“approved” and “unapproved”), their branded products, and sales volumes. …”

Data_Sheet_3_Bacillus subtilis Produces Amino Acids to Stimulate Protein Synthesis in Ruminal Tissue Explants via the Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subun... by Qiuju Wang (7400)

“…The addition of psilocybin upregulated the expression levels of PIK3CB and AKT. A significant decrease (p < 0.05) in PIK3CB and mTOR protein expression levels was detected after the addition of LY294002 and rapamycin. …”

Case fatality of acute coronary events is improving even among elderly patients; the FINAMI study 1995–2012 by Heli Koukkunen (4486945)

“…The incidence of MI decreased by −3.3%/year (95% CI −4.2; −2.4) in women aged 75–84 years, and by −1.2%/year (−1.9; −0.5) in women aged 85-99 years, but among men in these age-groups, only a non-significant reduction occurred. …”

Laboratory data. by Biniyam Tedla Mamo (20598461)

“…<div><p>Background</p><p>Neonatal sepsis is a leading cause of mortality and morbidity. To improve the clinical outcomes of neonates with sepsis, treatment should be based on bacteriological identification and antibiotic susceptibility. …”

Data from: Increased Soil Nitrogen Availability Suppresses Annual Soil Respiration in Mixed Temperate Forests Regardless of Acidification by David W. Frey (21072152)

“…This data publication includes data from a study investigating how soil N availability and acidity affect soil respiration and its plant- and decomposer-driven component fluxes. …”

JAGGED1-NOTCH regulates RPE proliferation and specification. by Jingxing Ou (153590)

“…<p>(<b>A–F</b>) Optic cups of the indicated genotypes were harvested at the indicated times and stained for JAGGED1. …”

image_7_Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells.PDF by Kornelis S. M. van der Geest (478975)

“…In addition, aging was associated with a decrease of nonclassic T helper 1 cells, as indicated by decreased percentages of CD161-expressing cells within the IFN-γ⁺ CD4⁺ T cell compartment of old subjects. …”

The role of TLR9 on <i>Leishmania amazonensis</i> infection and its influence on intranasal LaAg vaccine efficacy by Juliana Elena Silveira Pratti (6397262)

“…The increased TLR9^-/- mice susceptibility was accompanied by an increased IgG and IgG1 production; a decrease of IFN-γ in infected tissue, but not IL-4 and IL-10; and a decreased number of IFN-γ producing CD8⁺ T cells, but not CD4⁺ T cells in the lesion-draining lymph nodes. …”

miR-466c participates in the regulation of <i>Vegfa</i> expression. by Pia Laitinen (12329203)

“…Deletion of miR-466c resulted in a significant drop in miR-466c levels in the deletion cell line. qPCR for miR-669c, a miRNA expressed from the same cluster as miR-466c from Sfmbt2 gene intron 10, showed that CRISPR-Cas9-deletion of miR-466 precursor does not decrease the levels of miR-669c in the cells, whereas both strands of miR-466c are repressed. n = 1 E. …”

table_1_Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells.PDF by Kornelis S. M. van der Geest (478975)

“…In addition, aging was associated with a decrease of nonclassic T helper 1 cells, as indicated by decreased percentages of CD161-expressing cells within the IFN-γ⁺ CD4⁺ T cell compartment of old subjects. …”