Supplementary Material for: Age Dependency of Successful Recanalization in Anterior Circulation Stroke: The ENDOSTROKE Study by Singer O.C. (2884253)

“…<b><i>Results:</i></b> The median age was 68 years (25th and 75th percentiles: 56, 76 years), and the median National Institutes of Health Stroke Scale (NIHSS) score at admission was 16 (13, 19); 41% of the patients had a favorable (mRS scores 0-2), and 59% had an unfavorable (mRS scores 3-6) outcome; 83% reached TIMI 2-3 flow. …”

Data_Sheet_1_Long-term environmental enrichment is associated with better fornix microstructure in older adults.docx by Olga M. Klimecki (3179982)

“…Background<p>Sustained environmental enrichment (EE) through a variety of leisure activities may decrease the risk of developing Alzheimer’s disease. …”

Data_Sheet_1_Understanding public support for COVID-19 pandemic mitigation measures over time: Does it wear out?.docx by John B. F. De Wit (10800816)

“…Support for mitigation measures may also differ between population subgroups who experience different benefits and costs, and decrease over time, a phenomenon termed “pandemic fatigue.”…”

DataSheet1_Lorcaserin Inhibit Glucose-Stimulated Insulin Secretion and Calcium Influx in Murine Pancreatic Islets.docx by Muhan Jing (11651452)

“…It is known that the mCPP, a kind of 5-HT_2CR agonist, decreases plasma insulin concentration in mice and previous research in our laboratory found that mCPP inhibited glucose-stimulated insulin secretion (GSIS) by activating 5-HT_2CR on the β cells. …”

Data_Sheet_1_Estimation of potato above-ground biomass based on unmanned aerial vehicle red-green-blue images with different texture features and crop height.docx by Yang Liu (4829)

“…The results show that (i) potato crop height and AGB first increase and then decrease over the growth period; (ii) GDS and scales mainly affect the correlation between GLCM- and Gabor-based textures and AGB; (iii) to estimate AGB, GLCM-based textures of GDS1 and GDS30 work best when the GDS is between 1 and 5 cm and 10 and 60 cm, respectively (however, estimating potato AGB based on Gabor-based textures gradually deteriorates as the Gabor convolution kernel scale increases); (iv) the AGB estimation based on a single-type texture is not as good as estimates based on multi-resolution GLCM-based and multiscale Gabor-based textures (with the latter being the best); (v) different forms of textures combined with crop height using the LSSVM technique improved by 22.97, 14.63, 9.74, and 8.18% (normalized root mean square error) compared with using only all GLCM-based textures, all Gabor-based textures, the former combined with crop height, and the latter combined with crop height, respectively. …”

Method for the Large-Scale Synthesis of Multifunctional 1,4-Dihydro-pyrrolo[3,2‑<i>b</i>]pyrroles by Mariusz Tasior (1457731)

“…Simultaneously, the optimized conditions have finally allowed the synthesis of these extremely promising heterocycles in amounts of more than 10 g per run without a concomitant decrease in yield or product contamination. …”

DataSheet_1_The Transcription of ZIP9 Is Associated With the Macrophage Polarization and the Pathogenesis of Hepatocellular Carcinoma.pdf by Yingying Gou (12243224)

“…TAMs generated from human liver cancer tissues also displayed a decrease in ZIP9 transcription compared to paracarcinoma tissues. …”

Image_3_Relationship of iodine excess with thyroid function in 6-year-old children living in an iodine-replete area.tiff by Yun Jeong Lee (7305383)

“…Excess iodine was associated with a decrease in FT4 or T3 levels and an increase in TSH levels. …”

Urine effects on grass and legume nitrogen isotopic composition: Pronounced short-term dynamics of δ¹⁵N by Bettina Tonn (5678663)

“…We applied cattle urine to a mixture of <i>Lolium perenne</i> and <i>Trifolium repens</i> in a pot experiment. …”

DataSheet3_Prediction of the Molecular Mechanisms Underlying Erlong Zuoci Treatment of Age-Related Hearing Loss via Network Pharmacology-Based Analyses Combined with Experimental V... by Qing Liu (20889)

“…</p><p>Results: In total, 63 chemical compounds from ELZC and 365 putative ARHL-related targets were identified, and 1860 ARHL-related targets were collected from the OMIM and GeneCards. A total of 145 shared targets of ELZC and ARHL were acquired by Venn diagram analysis. …”

Image1_Effect of pro-inflammatory cytokine priming and storage temperature of the mesenchymal stromal cell (MSC) secretome on equine articular chondrocytes.TIF by Manon Jammes (16910904)

“…The three cytokines chosen for the MSC priming influenced MSC immunomodulator gene expression, although each cytokine led to a different pattern of MSC immunomodulation. The cytokine-primed CM had no major effect on eAC proliferation, with IL-1β and TNF-α slightly increasing collagen (types IIB and I) accumulation in eAC 3D cultures (particularly with the CM derived from MSCs primed with IL-1β), and IFN-γ leading to a marked decrease. …”

Soluble CD73 in Critically Ill Septic Patients – Data from the Prospective FINNAKI Study by Suvi T. Vaara (2504209)

“…</p><p>Conclusions</p><p>Compared to normal population, the sCD73 levels were generally low at 0h, showed a decrease to 24h, and later an increase by day 5. …”

Supplementary file 1_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.docx by Wentong Li (492392)

“…</p>Conclusion<p>This study elucidates the HSP90AA1-HSPA1B-DNAJB1 network as a key driver of VaD pathogenesis through dual mechanisms of protein homeostasis and immune reprogramming. …”

Rapamycin aggravates neurodegeneration in fly model of FXTAS. by Yunting Lin (405839)

“…<p>(<b>A</b>) (<b>i</b>) Rapamycin aggravates ommatidial degeneration of <i>GMR-GAL4>CGG₉₀</i> (4 days old after eclosion). …”

Genetic Variants of Pregnane X Receptor (PXR) and CYP2B6 Affect the Induction of Bupropion Hydroxylation by Sodium Ferulate by Lichen Gao (423659)

“…<i>NR1I2</i> TGT haplotype (-25385T+g.7635G+g.8055T) carriers exhibited a significantly decreased AUC ratio, compared with TGT noncarriers, in the basal states (7.6±1.0 versus 9.7±1.0), while this result wasn't observed in <i>CYP2B6*6</i> noncarriers. …”

Nationwide Trends in Bacterial Meningitis before the Introduction of 13-Valent Pneumococcal Conjugate Vaccine—Burkina Faso, 2011–2013 by Dinanibè Kambiré (2173702)

“…<div><p>Background</p><p>Following introduction of <i>Haemophilus influenzae</i> type b vaccine in 2006 and serogroup A meningococcal conjugate vaccine in 2010, <i>Streptococcus pneumoniae</i> (Sp) became the leading cause of bacterial meningitis in Burkina Faso. …”

Inadequate maternal weight gain in the third trimester increases the risk of intrauterine growth restriction in rural Bangladesh by S. M. Tafsir Hasan (5146871)

“…Inadequate third-trimester weight gain was defined as 4 kg or less irrespective of pre-gravid nutritional status. IUGR was defined as a birth weight below 2500 g in full-term newborns (LBW-Term), and a birth weight for gestational age and infant sex less than the 10^th percentile (SGA-10^th) and 2 standard deviations below the mean birth weight (SGA-2SD) based on the international newborn standards from the INTERGROWTH-21^st project. …”

Image_4_Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4+ T Cell Responses.TIF by M. Ayelén Milillo (4325953)

“…We also demonstrated that B. abortus RNA along with its lipoproteins decrease MHC-II surface expression predominantly by a mechanism of inhibition of MHC-II expression. …”

HGF, VEGF and the lack of EGF in glioma C6 CM induce NSCs transmigration across RBMECs. by Mónica Díaz-Coránguez (400103)

“…IP of VEGF reverses the decrease in TEER induced by glioma C6 CM whereas IP of EGF from astrocyte CM decreases TEER in a manner similar to that obtained with glioma C6 CM. …”

Data_Sheet_1_The BACH1 inhibitor ASP8731 inhibits inflammation and vaso-occlusion and induces fetal hemoglobin in sickle cell disease.PDF by John D. Belcher (9042980)

“…In pulmonary endothelial cells, ASP8731 decreased VCAM1 mRNA in response to TNF-α and blocked a decrease in glutathione in response to hemin. …”