Restricting CSPG Secretion to the Acute Stage after Injury Improves Functional Recovery by Asya Rolls (84466)

“…</p> <p>(L) Western blot analysis of CSPG levels in the control group (PBS) and in the groups receiving xyloside treatment on day 0 or day 2 after the injury (excised 7 d after the injury). β-actin was used as a control for protein levels. Fold decrease in CSPG levels, relative to PBS control, are shown (<i>n</i> = 3 mice per group).…”

table_1_Expression and Function of IL12/23 Related Cytokine Subunits (p35, p40, and p19) in Giant-Cell Arteritis Lesions: Contribution of p40 to Th1- and Th17-Mediated Inflammatory... by Georgina Espígol-Frigolé (5124590)

“…Background<p>Giant-cell arteritis (GCA) is considered a T helper (Th)1- and Th17-mediated disease. Interleukin (IL)-12 is a heterodimeric cytokine (p35/p40) involved in Th1 differentiation. …”

Hemophagocytic Lymphohistocytosis in the Chinese Han Population May Be Associated with an STXBP2 Gene Polymorphism by Li Yang (6520)

“…<div><p>Study Purpose</p><p>Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Table_1_MRI-Based Radiomics Nomogram: Prediction of Axillary Non-Sentinel Lymph Node Metastasis in Patients With Sentinel Lymph Node-Positive Breast Cancer.docx by Ya Qiu (12157977)

“…Background<p>Overtreatment of axillary lymph node dissection (ALND) may occur in patients with axillary positive sentinel lymph node (SLN) but negative non-SLN (NSLN). Developing a magnetic resonance imaging (MRI)-based radiomics nomogram to predict axillary NSLN metastasis in patients with SLN-positive breast cancer could effectively decrease the probability of overtreatment and optimize a personalized axillary surgical strategy.…”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Table_1_pcMSC Modulates Immune Dysregulation in Patients With COVID-19-Induced Refractory Acute Lung Injury.xlsx by Mei-Chuan Chen (143589)

“…Immune cell profiles showed an increase in the proportions of CD4⁺ T cells (namely, CD4⁺ naïve T cells and CD4⁺ memory T cell subtypes), Treg cells, CD19⁺ B cells (namely, CD19⁺ naïve B cells, CD27⁺ switched B cell subtypes) and dendritic cells, and a significant decrease in the proportion of CD14⁺ monocytes (namely, CD16^- classical and CD16⁺ non-classical subtypes), and plasma/plasmablast cells. …”

Viral ORF57 inhibits eIF2α phosphorylation through down-regulation of PKR pathway. by Nishi R. Sharma (4543936)

“…<p>(A) Diagrams of four major stress pathways leading to phosphorylation of eIF2α via different kinases. …”

Transcriptional effect of TRα2 knockdown on positively and negatively regulated T₃ target genes <i>in vivo</i>. by Hajer Guissouma (586934)

“…A decrease in TRα2 protein expression level is observed with shTRα2 compared to control (shCt). …”

Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects by Kaat Kehoe (5233382)

“…Serum PRCP activity in lean subjects was 0.83 ± 0.04 U/L and increased significantly with a rising BMI (p<0.001) and decreased upon weight loss (diet, p<0.05; bariatric surgery, p<0.001). …”

Table_1_Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance.xlsx by B. Leticia Rodriguez (1953484)

“…Classical Ly6C+ monocytes from ICB resistant tumors had a decrease in both Flt3 and PU.1 expression that prevented differentiation into dendritic cells/macrophages.…”

table_3_Expression and Function of IL12/23 Related Cytokine Subunits (p35, p40, and p19) in Giant-Cell Arteritis Lesions: Contribution of p40 to Th1- and Th17-Mediated Inflammatory... by Georgina Espígol-Frigolé (5124590)

“…Background<p>Giant-cell arteritis (GCA) is considered a T helper (Th)1- and Th17-mediated disease. Interleukin (IL)-12 is a heterodimeric cytokine (p35/p40) involved in Th1 differentiation. …”

TGF-β1 is required for NRP2-mediated EMT. by Camille Grandclement (215143)

“…Histone-H1 was used as a control of protein loading. Whereas only 10 µM of SB-431542 decreases the nuclear level of phosphorylated Smad2 in Colo320 cancer cells, doses of 50 µM should be used to decrease the nuclear level of phosphorylated Smad2 in HT29^NRP2 cancer cells. …”

DataSheet_1_pcMSC Modulates Immune Dysregulation in Patients With COVID-19-Induced Refractory Acute Lung Injury.docx by Mei-Chuan Chen (143589)

“…Immune cell profiles showed an increase in the proportions of CD4⁺ T cells (namely, CD4⁺ naïve T cells and CD4⁺ memory T cell subtypes), Treg cells, CD19⁺ B cells (namely, CD19⁺ naïve B cells, CD27⁺ switched B cell subtypes) and dendritic cells, and a significant decrease in the proportion of CD14⁺ monocytes (namely, CD16^- classical and CD16⁺ non-classical subtypes), and plasma/plasmablast cells. …”

<i>KIR</i> and <i>HLA</i> Genotypes Implicated in Reduced Killer Lymphocytes Immunity Are Associated with Vogt-Koyanagi-Harada Disease by Ralph D. Levinson (3142863)

“…The incidence of <i>Bx</i>-<i>KIR</i> genotypes was decreased in VKH patients (odds ratio [OR] 0.58, P = 0.007), due primarily to a decrease in centromeric <i>B-KIR</i> motif and its associated <i>KIRs 2DS2</i>, <i>2DL2</i>, <i>2DS3</i>, and <i>2DL5B</i>. …”

Presentation_1_Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance.pptx by B. Leticia Rodriguez (1953484)

“…Classical Ly6C+ monocytes from ICB resistant tumors had a decrease in both Flt3 and PU.1 expression that prevented differentiation into dendritic cells/macrophages.…”

Table_1_pcMSC Modulates Immune Dysregulation in Patients With COVID-19-Induced Refractory Acute Lung Injury.xlsx by Mei-Chuan Chen (143589)

“…Immune cell profiles showed an increase in the proportions of CD4⁺ T cells (namely, CD4⁺ naïve T cells and CD4⁺ memory T cell subtypes), Treg cells, CD19⁺ B cells (namely, CD19⁺ naïve B cells, CD27⁺ switched B cell subtypes) and dendritic cells, and a significant decrease in the proportion of CD14⁺ monocytes (namely, CD16^- classical and CD16⁺ non-classical subtypes), and plasma/plasmablast cells. …”

Combined Experimental and Computational Studies on Carbon−Carbon Reductive Elimination from Bis(hydrocarbyl) Complexes of (PCP)Ir by Rajshekhar Ghosh (1812388)

“…For R/R′ = Ph/Ph, Ph/Me, and Ph/CCPh, we obtain upper limits to the elimination rate; and for R/R′ = CCPh/CCPh, a lower limit. In general, the rates decrease (activation barriers increase) according to the following order: acetylide < vinyl ∼ Me < Ph. …”

Mitotic regeneration of IPhCs. by Tomokatsu Udagawa (11675636)

“…<p>(A) Experimental paradigm: DT was injected into P1 wild-type or <i>Lgr5</i>^<i>DTR/+</i> mice. …”