Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…In vivo studies showed that overall tumor metastasis decreased in 4T1 xenografts mice treated with MSN-PEG/TA 25 with a notable reduction in lung tumor metastasis. …”

Protective Role of Acidic pH-Activated Chloride Channel in Severe Acidosis-Induced Contraction from the Aorta of Spontaneously Hypertensive Rats by Zhiyong Ma (95708)

“…In the present study, we investigate whether this channel participates in reactions of the thoracic aorta to severe acidosis and whether it plays a role in hypertension. We measured isometric contraction in thoracic aorta rings from spontaneously hypertensive rats (SHRs) and normotensive Wistar rats. …”

Table_1_10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism.XLSX by Pei Fan (404125)

“…To the best of our knowledge, our results provide the first concrete evidence that 10-HDA-scavenged •OH could be a potential pharmacological application for maintaining vascular health.…”

DataSheet1_Activation of Nrf2 by Lithospermic Acid Ameliorates Myocardial Ischemia and Reperfusion Injury by Promoting Phosphorylation of AMP-Activated Protein Kinase α (AMPKα).ZIP... by Min Zhang (111999)

“…<p>Background: As a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, lithospermic acid (LA) has been identified as the pharmacological management for neuroprotection and hepatoprotection. …”

Image4_2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways.jpg by Tsung-Teng Huang (167578)

“…The main purpose of this study was to investigate the protective effect of THSG against bleomycin (BLM)-induced lung fibrosis in a murine model, and explore the underlying mechanisms of THSG in transforming growth factor-beta 1 (TGF-β1)-induced fibrogenesis using MRC-5 human lung fibroblast cells. …”

DataSheet_3_The value of metabolic LncRNAs in predicting prognosis and immunotherapy efficacy of gastric cancer.docx by Peizhun Du (14324136)

“…Introduction<p>As a unique feature of malignant tumors, abnormal metabolism can regulate the immune microenvironment of tumors. …”

Physiological and transcriptomic responses of Lanzhou Lily (<i>Lilium davidii</i>, var. unicolor) to cold stress by Xuehui Tian (5285726)

“…Comparative transcriptome profiling showed that a total of 238,109 differentially expressed genes were detected. …”

Synthesis and Characterization of Ru(II)–DMSO–Cl–Chalcone Complexes: DNA Binding, Nuclease, and Topoisomerase II Inhibitory Activity by Ruchi Gaur (1358721)

“…The molecular assembly of complex <b>5</b> using secondary interactions provides a butterfly structure. The binding of complexes with calf thymus DNA is monitored using UV–vis spectral titrations. …”

Table_1_Molecular Mechanism of the UDP-Glucuronosyltransferase 2B20-like Gene (AccUGT2B20-like) in Pesticide Resistance of Apis cerana cerana.XLSX by Xuepei Cui (9658271)

“…<p>UDP-glucuronosyltransferases (UGTs), being multifunctional detoxification enzymes, play a major role in the process of resistance to various pesticides in insects. …”

Data_Sheet_1_Alpine wetland degradation reduces carbon sequestration in the Zoige Plateau, China.docx by Ao Yang (2387728)

“…These results suggest that the capacity of carbon sequestration in the Zoige wetlands reduced with intensification of the degradation. This study provides a reference for sustainably managing and utilizing degraded wetlands under climate change.…”

DataSheet1_Clostridium butyricum Protects Against Pancreatic and Intestinal Injury After Severe Acute Pancreatitis via Downregulation of MMP9.ZIP by Qingqing Yan (752158)

“…In addition, to investigate the association between gut microbiota and MMP9 in intestinal injury during SAP, we established MMP9 stable knockdown Caco2 and HT29 cells in vitro and generated a MMP9 knockout (MMP9−/−) mouse model of SAP in vivo.…”

Substitution of dry corn grain by rehydrated and ensiled corn grain, finely or coarsely ground, on performance of young bulls finished in feedlot by Marlon Richard Hilário da Silva (5889929)

“…The experiment was conducted in blocks by weight, and bulls were randomly assigned into four groups of five animals each in a 2 × 2 factorial scheme. The factors evaluated were particle size (finely and coarsely ground) and two grain sources (dry ground corn and rehydrated corn grain silage). …”

Expression of lncRNA RGMB-AS1 and RGMB in lung adenocarcinoma tissues. by Ping Li (31981)

“…<p>(A) LncRNA RGMB-AS1 expression in lung adenocarcinoma tissues (Tumor group) was higher than in adjacent normal tissues (Normal group) (<i>P</i> < 0.05). …”

DataSheet_2_Global burden of major gastrointestinal cancers and its association with socioeconomics, 1990–2019.pdf by Mei-Zhu Hong (518188)

“…</p>Conclusion<p>There is a profound association between socioeconomics and burden of common cancers of the gastrointestinal tract. …”

Shrimp allergen extract (SAE) immunotherapy preventing the development of allergies. by Honey Dzikri Marhaeny (20480031)

“…SAE desensitization successfully decreased transcription of (A) <i>FcεR1α</i> mRNA (n = 6 mice per group) and (B) IL-4 mRNA—relative to NC—in the ileal tissue (n = 3 mice per group), and suppressed the production of the pro-inflammatory cytokine (C) IL-4 in serum (n = 6 mice per group). …”

Image_1_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.tif by Dong-sheng Di (11634688)

“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”

Image 1_Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus.pdf by Guanfei Zhao (3815596)

“…CD8⁺ T naïve (Tn) cell MMP-Low, CD8⁺ T effector memory cell MMP-Low, CD8⁺ T central memory (Tcm) cell MMP-Low, and SCMM-CD8⁺ Tn cells demonstrated a moderate diagnostic value for SLE, with an area under the curve (AUC) above 0.8. …”

The results of the microarray analysis revealed the GATA3-regulated cytokine and cytokine receptor genes in Th2 cells. by Tetsuya Sasaki (423108)

“…<p>(<b>A</b>), The names of the selected 24 cytokine genes. …”

Data_Sheet_1_Pyruvate Might Bridge Gut Microbiota and Muscle Health in Aging Mice After Chronic High Dose of Leucine Supplementation.docx by Yuxiao Liao (11735678)

“…</p><p>Conclusions: Chronic high dose of leucine supplementation changed gut microbiota composition and increased pyruvate levels in the feces, which possibly provides a novel direction for promoting muscle health in aging mice.…”

Table_1_Carbon Amendments Influence Composition and Functional Capacities of Indigenous Soil Microbiomes.XLSX by José Pablo Dundore-Arias (6517574)

“…Mesocosms were established with soil from two field sites varying in soil organic matter content (low organic matter, LOM; high organic matter, HOM), that were amended at intervals over nine months with low or high dose solutions of glucose, fructose, malic acid, a mixture of these compounds, or water only (non-amended control). …”