Small molecule inhibitors of GSK-3β impede VEEV replication. by Kylene Kehn-Hall (45085)

“…<p><b>A</b>) U87MG astrocytes were treated with BIO (10, 5, 2.5, or 1.25 µM) and cell viability assayed 24 hours later by CellTiter Glo Assay (Promega). …”

Image9_Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic progen... by Osvaldo Contreras (780538)

“…<p>Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA receptors and mediating signalling pathways that regulate embryonic development, wound healing, carcinogenesis, and fibrosis, via effects on cell migration, proliferation and differentiation. …”

Table_2_Molecular Mechanism of the UDP-Glucuronosyltransferase 2B20-like Gene (AccUGT2B20-like) in Pesticide Resistance of Apis cerana cerana.XLSX by Xuepei Cui (9658271)

“…<p>UDP-glucuronosyltransferases (UGTs), being multifunctional detoxification enzymes, play a major role in the process of resistance to various pesticides in insects. …”

Table 14_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx by Yanyao Lu (22163632)

“…However, the specific effects of different drainage durations on soil microorganisms and metabolites remain unclear. This study adopted a multi-omics research method. After nontargeted metabolomics analysis of lipids as the main metabolite, microbial diversity analysis and lipidomics analysis were conducted to determine the main influencing factors. …”

DataSheet_2_Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction... by Siqi Xu (429196)

“…We confirmed this mechanistic effect in a CLP-induced sepsis model of intestinal SIRT3 conditional-knockout mice, and found that melatonin preserved mitochondrial function and induced autophagy of small-intestine epithelial cells; these effects were dependent on SIRT3 activation. …”

Data_Sheet_1_Geographic Variation in the Petiole–Lamina Relationship of 325 Eastern Qinghai–Tibetan Woody Species: Analysis in Three Dimensions.xlsx by Yanan Li (94033)

“…Understanding environmental gradients in the relationship and its underlying mechanisms remains a critical challenge for ecologists. We investigated the possible scaling of the petiole–lamina relationships in three dimensions, i.e., petiole length (PL) vs. lamina length (LL), petiole cross sectional area (PCA) vs. lamina area (LA), and petiole mass (PM) vs. lamina mass (LM), for 325 Qinghai–Tibetan woody species, and examined their relation to leaf form, altitude, climate, and vegetation types. …”

Data_Sheet_1_Adjuvant Chemotherapy and Tumor Sidedness in Stage II Colon Cancer: Analysis of the National Cancer Data Base.PDF by Shiva Kumar R. Mukkamalla (9378413)

“…We examined AC administration in this population and its effect on overall survival (OS) for available patient, tumor, and treatment characteristics</p><p>Methods: Using National Cancer Data Base, a cohort of 42,971 stage II CC patients diagnosed from 2004 to 2009, who underwent surgery with curative intent, was identified. …”

Selective Inhibitors of Janus Kinase 3 Modify Responses to Lipopolysaccharides by Increasing the Interleukin-10-to-Tumor Necrosis Factor α Ratio by Julian Laux (13047767)

Image_4_Effect of four fluoroquinolones on the viability of bladder cancer cells in 2D and 3D cultures.tif by Tomasz Kloskowski (622176)

“…</p>Results and Discussion<p>All tested fluoroquinolones in 2D culture decreased the viability of both tested cell lines in a dose- and timedependent manner. …”

DataSheet1_Artemisinin relieves myocardial ischemia-reperfusion injury via modulating miR-29b-3p and hemicentin 1.PDF by Junyu Han (13232310)

“…</p><p>Conclusion: This study demonstrated the functional role of the ARS/miR-29b-3p/HMCN1 axis in alleviating myocardial I/R injury, which provided a new direction for myocardial I/R injury therapy.…”

Image2_Effects of Temperature and Additives on NOx Emission From Combustion of Fast-Growing Grass.PNG by Haili Liu (395833)

“…<p>Fast-growing grass, as a popular renewable energy, is low in sulfur content, so NO_x is the major pollutant during its combustion. …”

Characterization of Genome-Wide Association-Identified Variants for Atrial Fibrillation in African Americans by Jessica T. Delaney (181642)

“…<div><h3>Background</h3><p>Despite a greater burden of risk factors, atrial fibrillation (AF) is less common among African Americans than European-descent populations. …”

Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff by Yulia Dwi Setia (21590591)

“…</p>Discussion<p>Our findings suggested that E. pragensis infection induces a mucosal barrier dysfunction in the early phase of the infection, which possibly causes the tissue invasion of bacteria in the large intestine. …”

DataSheet6_Single-cell transcriptome dynamics of the autotaxin-lysophosphatidic acid axis during muscle regeneration reveal proliferative effects in mesenchymal fibro-adipogenic pr... by Osvaldo Contreras (780538)

“…<p>Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA receptors and mediating signalling pathways that regulate embryonic development, wound healing, carcinogenesis, and fibrosis, via effects on cell migration, proliferation and differentiation. …”

Image_2_Longitudinal Changes in Diffusion Tensor Imaging Following Mild Traumatic Brain Injury and Correlation With Outcome.tif by Bo Yin (681235)

“…Neuroimaging was obtained within 7 days post-injury for acute scans and repeated at 1 and 3 months post-injury. Using a region-of-interest-based approach, tract-based spatial statistics was used to conduct voxel-wise analysis on diffusion changes in mTBI and was compared to those of healthy matched controls, scanned during the same time period and rescanned with an interval similar to that of patients. …”

Table_2_From numbers to medical knowledge: harnessing combinatorial data patterns to predict COVID-19 resource needs and distinguish patient subsets.DOCX by Parthkumar H. Satashia (17354863)

“…New methods could also identify, upon admission, a subset of COVID-19 patients that reveal inflammation. …”

Data Sheet 2_Neonatal encephalopathy due to birth asphyxia and trauma: global trends and disparities.zip by Fengling Du (22229149)

“…Background<p>Neonatal encephalopathy due to birth asphyxia and trauma (NE-BAT) is a leading cause of neonatal mortality and long-term neurodevelopmental disabilities, particularly in low- and middle-income regions.…”

Data_Sheet_1_Alteration of pro-carcinogenic gut microbiota is associated with clear cell renal cell carcinoma tumorigenesis.docx by Bo-Yu Yang (12267206)

“…Here we aim to elucidate the association of specific gut bacteria and their metabolites with ccRCC.</p>Methods<p>In a pilot case-control study among 30 ccRCC patients (RCC group) and 30 healthy controls (Control group), 16S ribosomal RNA (rRNA) gene sequencing were analyzed from fecal samples collected prior to surgery or hospitalization. …”

Table5_Correlation Between Immune-Related Genes and Tumor-Infiltrating Immune Cells With the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer.XLSX by Yan Zhou (6523)

“…Among the many biomarkers predicting the efficacy of NAC, immune-related biomarkers, such as immune-related genes and tumor-infiltrating lymphocytes (TILs), play a key role.</p><p>Methods: We analyzed gene expression from several datasets in the Gene Expression Omnibus (GEO) database and evaluated the relative proportion of immune cells using the CIBERSORT method. …”

Table_2_The Impact of Chronic Heat Stress on the Growth, Survival, Feeding, and Differential Gene Expression in the Sea Urchin Strongylocentrotus intermedius.DOC by Yaoyao Zhan (359351)

“…Further Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analyses revealed that these DEGs mainly enriched the functional categories of ribosome, protein processing in endoplasmic reticulum, and prion diseases. A total of 732 temperature-induced expressed genes, such as ATP5, heat shock protein 70, and heat shock protein 90, were identified as candidates that were closely correlated with heat resistance in S. intermedius. …”