Data_Sheet_1_Metabolomics combined with intestinal microbiota reveals the mechanism of compound Qilian tablets against diabetic retinopathy.PDF by Jiangwei Jia (19431646)

“…Compound Qilian tablets (CQLT) is a traditional Chinese medicine (TCM) developed for treating DR, but its mechanism is still unclear. …”

Dipeptide makeup of ancient proteins. by Gustavo Caetano-Anollés (65405)

“…<p>A. The distribution of dipeptide compositions in proteins shows remarkable conservation along the FF timeline. …”

Data Sheet 2_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -ind... by Yanping Wang (275956)

“…</p>Methods<p>In this study, the chronic unpredictable mild stress (CUMS) method was used to establish a rat model of depression to investigate the ameliorative effects of HLTP on depression.…”

Schematic summary: MC immuno-phenotype and MC-CD8+ T-cell interactions in healthy compared to lesional AA skin. by Marta Bertolini (564966)

“…Most of them express IL-10, TGFβ1 while only some express OX40L and PD-L1 and very few express CD30L and ICAM-1 (A). In lesional AA skin, the degranulation of MCs is increased (release of tryptase, heparin and histamine) and the expression of tryptase is increased, while the contents of TGFbeta1, IL-10 are decreased. …”

Table_2_Associations between plasma metal elements and risk of cognitive impairment among Chinese older adults.DOCX by Xin Wang (91924)

“…Moreover, subgroup analyses by age, sex, and body mass index suggested a consistent significant correlation (p < 0.05).…”

Temporal and spatial variation of potassium balance in agricultural land at national and regional levels in China by Yingxia Liu (792213)

“…<div><p>Linking potassium (K) balance to soil fertility creates a valuable indicator for sustainability assessment in agricultural land-use systems. …”

Recombinant PLTP induced FLS proliferation and cytokine production independently of its lipid transfer ability. by Rachel Audo (96127)

“…<p><b>(A)</b> RA-FLS were stimulated for 48 hours with 2μg/ml of PLTP or heat inactivated-PLTP (heated-PLTP) and proliferation was evaluated using [³H] thymidine incorporation during the last day of stimulation. …”

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts by Yu-Tse Lee (19944891)

“…In vivo studies showed that overall tumor metastasis decreased in 4T1 xenografts mice treated with MSN-PEG/TA 25 with a notable reduction in lung tumor metastasis. …”

Image_1_Geographic Variation in the Petiole–Lamina Relationship of 325 Eastern Qinghai–Tibetan Woody Species: Analysis in Three Dimensions.pdf by Yanan Li (94033)

“…Understanding environmental gradients in the relationship and its underlying mechanisms remains a critical challenge for ecologists. We investigated the possible scaling of the petiole–lamina relationships in three dimensions, i.e., petiole length (PL) vs. lamina length (LL), petiole cross sectional area (PCA) vs. lamina area (LA), and petiole mass (PM) vs. lamina mass (LM), for 325 Qinghai–Tibetan woody species, and examined their relation to leaf form, altitude, climate, and vegetation types. …”

Effect of SILD on STZ-diabetic kidney: modulation of macrophage infiltration. by Mary Anna Venneri (737094)

“…<p>(A) Representative photomicrographs of H&E-stained kidneys (×200 magnification) on harvesting show normal structure in the CTRL and SILD, mild mesangial expansion and tubular damage in the STZ, and normal structure in the STZ+SILD group (bar represents 100 μm).…”

DataSheet1_Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway.XLSX by Qin Ru (11623021)

“…The combination of network pharmacology approaches with experimental validation may offer a useful tool to characterize the molecular mechanism of multicomponent complexes.…”

Table1_HSP90 Inhibitor 17-AAG Attenuates Nucleus Pulposus Inflammation and Catabolism Induced by M1-Polarized Macrophages.DOCX by Shuo Zhang (30844)

“…In conclusion, HSP90 inhibitor 17-AAG attenuates NP inflammation and catabolism induced by M1 macrophages, suggesting 17-AAG as a promising candidate for IVDD treatment.</p>…”

MCT4/CD147 transporter complex-associated cell proliferation, migration and invasion in U87 and U251 cell lines. by Chen Gao (159491)

“…<p><b>A.</b> Cell proliferation curves of U251 cells. …”

Table2_Deciphering the mechanism of PSORI-CM02 in suppressing keratinocyte proliferation through the mTOR/HK2/glycolysis axis.XLSX by Maojie Wang (807580)

“…<p>Hyperplasia of epidermal keratinocytes that depend on glycolysis is a new hallmark of psoriasis pathogenesis. Our previous studies demonstrated that PSORI-CM02 could halt the pathological progression of psoriasis by targeting inflammatory response and angiogenesis, but its effect(s) and mechanism(s) on proliferating keratinocytes remained unclear. …”

Spanish real-world experience with fingolimod in relapsing-remitting multiple sclerosis patients: MS NEXT study by Francisco Barrero (8662047)

“…</p><p>Methods</p><p>This observational, retrospective, multicentre, nationwide study was performed at 56 Spanish hospitals and involved 804 RRMS patients who received oral fingolimod (0.5 mg) since November 2011, with a minimum follow-up of 12 months.</p><p>Results</p><p>The mean annualized relapse rate (ARR) in the year before fingolimod was 1.08 and the median EDSS was 3; patients were exposed to fingolimod for 2.2 years as average; regarding magnetic resonance imaging (MRI) activity, more than half of the patients had >20 lesions at baseline. …”

Table_3_Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis.xlsx by Jipeng Yan (8473710)

“…Notably, 5 optimal ASV-based microbial markers were identified as the diagnostic model of AL amyloidosis and the AUC value of the train set and the test set was 0.8549 (95% CI 0.7310-0.9789) and 0.8025 (95% CI 0.5771-1), respectively. With a median follow-up of 19.0 months, further subgroup analysis also demonstrated some key gut microbial markers were related to disease severity, treatment response, and even prognosis of patients with AL amyloidosis.…”

Image_1_Precision immunointerception of EGFR-driven tumorigenesis for lung cancer prevention.jpeg by Jing Pan (95938)

“…In this study, we identified immunogenic epitopes for the common EGFR mutations in humans and formulated a multi-peptide vaccine (E^mut Vax) targeting the EGFR L858R, T790M, and Del19 mutations. …”

Image_5_Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity.tif by Laura Kröhn (17011479)

“…However, higher IL37 expression correlated with a reduced proinflammatory cytokine response in murine colonic organoids. …”

Data_Sheet_2_RETRACTED: Endothelial-Monocyte Activating Polypeptide II Suppresses the In Vitro Glioblastoma-Induced Angiogenesis by Inducing Autophagy.DOC by Zhiqing Li (174007)

“…<p>The obstacle in delivering therapeutics to glioblastoma (GBM) is tumor-induced angiogenesis which leads to the formation of abnormal vessels and a dysfunctional blood-tumor barrier. Here, we elucidated the effect of endothelial-monocyte activating polypeptide II (EMAP II) on the GBM-induced angiogenesis as well as its potential mechanisms. …”

Image_6_Response of bacterial communities (Marivita, Marinobacter, and Oceanicaulis) in the phycosphere to the growth of Phaeodactylum tricornutum in different inorganic nitrogen s... by Xiaoxue Wei (14672540)

“…Our results explain when and how the phycosphere bacterial communities responded to algal biomass variations. The study provides a foundation for the quantitative relationship among nutrients, microalgae, and bacteria in this system.…”