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27161
Image_8_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27162
Image_4_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27163
N<sup>6</sup>-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon blac...
Published 2019“…We found that both of m<sup>6</sup>A modifications of pri-miRNA-126 and its binding with DGCR8 were decreased after CB treatment, which resulted in the reduction of mature miRNA-126 accompanied by accumulation of unprocessed pri-miRNA-126. …”
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27164
Table_1_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.DOCX
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27165
Image_6_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27166
Image_7_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27167
Image_5_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.TIF
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27168
Image_3_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.TIF
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27169
Image_2_2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression.JPEG
Published 2021“…</p><p>Results: 2ME significantly decreased all lung edema parameters, neutrophil infiltration, oxidative stress, proinflammatory cytokine production, lung cell apoptosis, tight junction protein disruption, and lung tissue injury in the IR-induced acute lung inflammation model. 2ME also increased the expression of the AnxA1 mRNA and protein and suppressed the activation of nuclear factor-κB (NF-κB). …”
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27170
DataSheet_2_Immunotherapeutic Effects of Different Doses of Mycobacterium tuberculosis ag85a/b DNA Vaccine Delivered by Electroporation.pdf
Published 2022“…</p>Results<p>Compared with the phosphate-buffered saline (PBS) group, the CD4<sup>+</sup>IFN-γ<sup>+</sup> T cells% in whole blood from 200 µg DNA IM group and four DNA EP groups increased significantly (P<0.05), CD8<sup>+</sup>IFN-γ<sup>+</sup> T cells% (in 200 μg DNA EP group), CD4<sup>+</sup>IL-4<sup>+</sup> T cells% (50 μg DNA IM group) and CD8<sup>+</sup>IL-4<sup>+</sup> T cells% (50 μg and 100 μg DNA IM group, 100 μg and 200 μg DNA EP group) increased significantly only in a few DNA groups (P< 0.05). The CD4<sup>+</sup>CD25<sup>+</sup> Treg cells% decreased significantly in all DNA vaccine groups (P<0.01). …”
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27171
DataSheet_1_Immunotherapeutic Effects of Different Doses of Mycobacterium tuberculosis ag85a/b DNA Vaccine Delivered by Electroporation.pdf
Published 2022“…</p>Results<p>Compared with the phosphate-buffered saline (PBS) group, the CD4<sup>+</sup>IFN-γ<sup>+</sup> T cells% in whole blood from 200 µg DNA IM group and four DNA EP groups increased significantly (P<0.05), CD8<sup>+</sup>IFN-γ<sup>+</sup> T cells% (in 200 μg DNA EP group), CD4<sup>+</sup>IL-4<sup>+</sup> T cells% (50 μg DNA IM group) and CD8<sup>+</sup>IL-4<sup>+</sup> T cells% (50 μg and 100 μg DNA IM group, 100 μg and 200 μg DNA EP group) increased significantly only in a few DNA groups (P< 0.05). The CD4<sup>+</sup>CD25<sup>+</sup> Treg cells% decreased significantly in all DNA vaccine groups (P<0.01). …”
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27172
Relative abundance of (A) <i>Hypocreales</i>, (B), <i>Aspergillus</i>, (C) <i>Malasseziales</i>, and (D) Cladosporium identified in the synovial fluid of RA patients and healthy co...
Published 2019“…<p>Data determined by the amplification and sequencing of the ITS2 gene. (A) The relative abundance of order <i>Hypocreales</i> was increased in synovial fluid of RA patients relative to healthy control synovial fluid. …”
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27173
DataSheet_1_RelA Is an Essential Target for Enhancing Cellular Responses to the DNA Repair/Ref-1 Redox Signaling Protein and Restoring Perturbated Cellular Redox Homeostasis in Mou...
Published 2022“…Gene expression analysis demonstrated that Ref-1 inhibitors significantly decreased IL-8, FOSB, and c-Jun when functional RelA is present. …”
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27174
Data_Sheet_1_Non-canonical Interaction Between O-Linked N-Acetylglucosamine Transferase and miR-146a-5p Aggravates High Glucose-Induced Endothelial Inflammation.PDF
Published 2020“…Real time PCR analysis found that miR-146a-5p was decreased in HG- and glucosamine-stimulated HAECs. …”
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27175
Serum LRG levels in patients with DM-IP and the HC, and changes in serum LRG levels at baseline measurement and at 2, 4, and 8 weeks after the initiation of treatment.
Published 2020“…<p>The serum LRG levels of the DM-IP patients were higher than those of the HC (A). The serum LRG levels at 2, 4, and 8 weeks after the initiation of treatment were significantly decreased in comparison with those before treatment (B). …”
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27176
C-terminal regions are required for interaction.
Published 2010“…Deletion of the C-terminal of RipA decreased the intensity of interaction and the C-terminal 25 amino acids of RipA were sufficient for interaction with PBP1. …”
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27177
Empirical Bayesian Random Censoring Threshold Model Improves Detection of Differentially Abundant Proteins
Published 2014“…A challenge in proteomics is that many observations are missing with the probability of missingness increasing as abundance decreases. …”
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27178
Synthesis and Molecular Structure of Gold Triarylcorroles
Published 2011“…A number of third-row transition-metal corroles have remained elusive as synthetic targets until now, notably osmium, platinum, and gold corroles. …”
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27179
Volcano plots of whole body, plasma and hepatic features in the blockade arm, including the RD, WDD, WDB and WDO Groups.
Published 2017“…The Pie Plots <b>[D]</b> represent a summary of the features that increased, decreased or did not change with diet treatment in each comparison.…”
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27180
Quantitative RT-qPCR demonstrate that Tat complex modulates expression of C5, CRLF2, APBA1, and BDNF.
Published 2017“…Significance was determined using a Wilcoxon signed-rank test. Error bars represent the median ± S.D.; **P < 0.01.…”