A possible involvement of the IκBζ pathway in IL-17A-induced hypercontractility. by Hirotada Akiho (559455)

“…Genes with significant changes in expression are coloured in red (increased) or blue (decreased). (<b>C</b>) Immunohistochemical staining for NFκB p65 protein in MS treated with or without IL-17A and IL-1β for 1 hr. …”

MiR-99a gene therapy attenuates cardiac hypertrophy in a mice model with TAC. by Qiaoling Li (290816)

“…BNP, β-MHC, PPAR-α, ACTA1, Hif-α, GLUT1 and HK2 levels were strongly increased in lenti-GFP treated hearts, but attenuated in lenti-99a treated hearts. Serca2a was decreased after surgery, but there was no significant difference in Serca2a expression among these three groups. …”

A Novel Bacterial Pathogen of <i>Biomphalaria glabrata</i>: A Potential Weapon for Schistosomiasis Control? by David Duval (178941)

“…Various research strategies and treatment programs for achieving the objective of eradicating schistosomiasis within a decade have been recommended and supported by the World Health Organization. …”

H Ferritin Gene Silencing in a Human Metastatic Melanoma Cell Line: A Proteomic Analysis by Maddalena Di Sanzo (713542)

“…In vitro assays confirmed that the FHC-silenced MM07_m cells are characterized by a decreased growth activity, a reduced invasiveness, and a reduced cell adhesion capability. …”

DataSheet_1_bub1 as a potential oncogene and a prognostic biomarker for neuroblastoma.xlsx by Jingjing Song (711775)

“…This study aimed to identify a novel oncogene that could be used as a biomarker informing the prognosis of neuroblastoma, and to predict its biological functions, using bioinformatics and molecular biology tools.…”

Ceruloplasmin Is a Potential Biomarker for aGvHD following Allogeneic Hematopoietic Stem Cell Transplantation by Meng Lv (367612)

“…The plasma ceruloplasmin levels were significantly increased during the period of aGvHD onset and were markedly decreased as aGvHD resolved. …”

Table 1_Microplastics in focus: a silent disruptor of liver health- a systematic review.docx by Zahra Beyzaei (9911886)

“…<p>Micro- and nanoplastics (MNPs) are widespread environmental contaminants, yet their impact on human liver health is not fully understood. We conducted a systematic review of 25 experimental, observational, and organoid-based studies published between 2022 and 2025 that investigated the hepatotoxic effects of polystyrene micro- and nanoplastics (PS-MPs/NPs). …”

H Ferritin Gene Silencing in a Human Metastatic Melanoma Cell Line: A Proteomic Analysis by Maddalena Di Sanzo (713542)

“…In vitro assays confirmed that the FHC-silenced MM07_m cells are characterized by a decreased growth activity, a reduced invasiveness, and a reduced cell adhesion capability. …”

Table_1_Bather Shedding as a Source of Human Fecal Markers to a Recreational Beach.xlsx by Dong Li (212687)

“…Offshore sources appeared unlikely, since FIB and fecal markers decreased along a spatial gradient from the surf zone toward nearshore and offshore ocean waters. …”

H Ferritin Gene Silencing in a Human Metastatic Melanoma Cell Line: A Proteomic Analysis by Maddalena Di Sanzo (713542)

“…In vitro assays confirmed that the FHC-silenced MM07_m cells are characterized by a decreased growth activity, a reduced invasiveness, and a reduced cell adhesion capability. …”

The NRF2 transcription factor plays a dual role in colorectal cancer: A systematic review by C. Gonzalez-Donquiles (4033610)

“…This predominantly exerts a cytoprotective effect on cells and decreases risk of colorectal cancer. …”

H Ferritin Gene Silencing in a Human Metastatic Melanoma Cell Line: A Proteomic Analysis by Maddalena Di Sanzo (713542)

“…In vitro assays confirmed that the FHC-silenced MM07_m cells are characterized by a decreased growth activity, a reduced invasiveness, and a reduced cell adhesion capability. …”

Evaluation of a transdiagnostic psychodynamic online intervention to support return to work: A randomized controlled trial by Rüdiger Zwerenz (3453260)

“…To that purpose we devised a transdiagnostic psychodynamic online intervention to facilitate return to work, focusing on interpersonal conflicts at the workplace often responsible for work-related stress.…”

H Ferritin Gene Silencing in a Human Metastatic Melanoma Cell Line: A Proteomic Analysis by Maddalena Di Sanzo (713542)

“…In vitro assays confirmed that the FHC-silenced MM07_m cells are characterized by a decreased growth activity, a reduced invasiveness, and a reduced cell adhesion capability. …”

Excel spreadsheet containing, in separate sheets, the underlying numerical data and statistical analysis for Fig panels 1C, 1F, 2A, 2B, 2C, 2D, 2E, 3A, 3F, 3G, 3I, 3L, 3M, 4C, 4E,... by Zhengchang Wu (140532)

Differential suppression of a gelsolin sequence-tagged reporter gene by miR-133a isomiRs. by Mary K. McGahon (422181)

“…Cells were imaged and analysed for both green and red fluorescence intensity. A decrease in red/green ratio <i>vs</i> NTC indicates downregulation of target gene expression. …”

2‑Chloro-4-[[(1<i>R</i>,2<i>R</i>)‑2-hydroxy-2-methyl-cyclopentyl]amino]-3-methyl-benzonitrile: A Transdermal Selective Androgen Receptor Modulator (SARM) for Muscle Atrophy by Ashraf Saeed (1416946)

“…A transdermal SARM has a potential to have therapeutic benefit through anabolic activity in muscle while sparing undesired effects of benign prostate hyperplasia (BPH) and liver-mediated decrease in HDL-C. 2-Chloro-4-[(2-hydroxy-2-methyl-cyclopentyl)­amino]-3-methyl-benzonitrile <b>6</b> showed the desired muscle and prostate effects in a preclinical ORX rat model. …”

Video2_A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome.AVI by Mariam G. Aslanyan (6645584)

“…<p>Establishment and maintenance of the primary cilium as a signaling-competent organelle requires a high degree of fine tuning, which is at least in part achieved by a variety of post-translational modifications. …”

Video3_A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome.AVI by Mariam G. Aslanyan (6645584)

“…<p>Establishment and maintenance of the primary cilium as a signaling-competent organelle requires a high degree of fine tuning, which is at least in part achieved by a variety of post-translational modifications. …”

Mcl-1 degradation is slowed by a T163E mutation (but not T163A) in transfected CHO cells. by Shanna K. Nifoussi (128297)

“…<p><b>A:</b> CHO cells were transfected with WT-Mcl-1 and incubated in the presence of LiCl (+LiCl; 20 mM) or in its absence (−LiCl) where 20 mM NaCl was added in the latter case. …”