Real-world mepolizumab treatment in patients with severe asthma decreased exacerbations, oral corticosteroid use, and healthcare resource utilization and costs over 4 years: a retrospective analysis by Wendy C. Moore (10682686)

“…This study evaluated the real-world impact of mepolizumab treatment in patients with severe asthma over a 4-year follow-up period.</p> <p>This was a retrospective cohort study of patients with asthma initiating mepolizumab (index date: first claim, November 2015–September 2019) using the Merative MarketScan Commercial and Medicare Databases. …”

Male <i>Frem1</i>^eyes2/eyes2 mice on a C57BL6 background have decreased anogenital distance. by Tyler F. Beck (387827)

A neurotensin receptor antagonist SR142948 dose-dependently decreased wakefulness time and duration during the lights on period in wild-type mice, but not in orexin neuron-ablated mice. by Naoki Furutani (169799)

Abdominal surgery (AS) decreased plasma levels of acyl-ghrelin (A) in vehicle or RKT pretreated mice, while there was no significant difference in insulin (B) and leptin (C) levels among the treatments. by Lixin Wang (343011)

Oligomeric Aβ₄₂-induced neuronal cell death was decreased by increased IL-10 secreted from hASC and/or murine BV2 cells. by Saeromi Kim (132677)

Image_1_Reaching and maintaining higher dietary diversity is associated with decreased risk of all-cause mortality: A longitudinal study from the China Health and Nutrition Survey.jpg by Xiaochen Qu (13861271)

“…In summary, reaching and maintaining a higher DDS was associated with a decreased risk of all-cause mortality. …”

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

DataSheet1_Pharmacological inhibition of receptor protein tyrosine phosphatase β/ζ decreases Aβ plaques and neuroinflammation in the hippocampus of APP/PS1 mice.docx by Teresa Fontán-Baselga (20392470)

“…In addition, we observed a significant decrease in the number and size of astrocytes in both sexes and in the number of microglial cells in a sex-dependent manner. …”

Supplementary Material for: A Polymorphism in the Gene Encoding the Insulin Receptor Binding Protein ENPP-1 Is Associated with Decreased Glomerular Filtration Rate in an Under-Investigated Indigenous African Population by Cave E.M. (9719192)

“…<b><i>Conclusion:</i></b> The rs1044498 A allele was significantly associated with lower eGFR levels in a cohort of apparently healthy Black South Africans, through an unknown mechanism that was independent of insulin resistance. …”

DataSheet1_Gestational intermittent hypoxia reduces mandibular growth with decreased Sox9 expression and increased Hif1a expression in male offspring rats.docx by Takumi Suzuki (12687350)

The induced knockdown of GmCAD receptor protein encoding gene in <i>Galleria mellonella</i> decreased the insect susceptibility to a <i>Photorhabdus akhurstii</i> oral toxin by Tushar K. Dutta (9406648)

As the number of infections <i>I</i> in a given county increases, the variance in exponential growth rate, Var(Δ<i>I</i>/<i>I</i>), decreases as . by Calvin Pozderac (10451496)

Decreased Akt-FoxO1/FoxO3a phosphorylation of Tsc1 KO naïve CD8⁺T cells in response to IL-7. by Lianjun Zhang (181973)

Supplementary Table 1 from A Novel Tankyrase Inhibitor Decreases Canonical Wnt Signaling in Colon Carcinoma Cells and Reduces Tumor Growth in Conditional APC Mutant Mice by Jo Waaler (1970758)

GXM decreases the trans-endothelial electrical resistance (TEER) and transmigration of <i>C</i>. <i>neoformans</i> through HBECs in a blood brain barrier (BBB) model. by Hiu Ham Lee (15374677)

Expression of genes that were decreased below a 1.5-fold cut-off in THP-1 monocytes treated with control medium or cigarette smoke extract for 8 hours. by William R. Wright (182615)

Clutches from <i>cd9b</i> mutant pairs, produced by IVF, have a decreased clutch size and lower percentage of eggs fertilised per clutch. by Sarah Greaves (11772721)

“…<p>The number of eggs is significantly decreased in clutches from <i>cd9b</i> mutant pairs (A). …”

Six-week-old neurons formed after a pSE insult show decreased scaffolding protein expression but unaltered expression of adhesion molecules important at excitatory synapses. by Johanna Jackson (325502)

Seed setting (A, B), pollen viability (C) and endogenous OsSpo11-4 expression (D) were decreased in OsSpo11-4 RNAi lines. by Xiao Jing An (219627)

Image_1_Mice with lung airway ciliopathy develop persistent Mycobacterium abscessus lung infection and have a proinflammatory lung phenotype associated with decreased T regulatory cells.jpeg by Audrey Nava (14173695)

“…T cells subset analysis showed a decrease in the percentage of CD4⁺FoxP3⁺ T cells in the total lymphocyte population in the lungs of IFT88 KO mice relative to IFT88 control mice. …”