Heat map analysis and the relative expression of proteins in pancreas at the termination of the experiment. by Christopher Mayer (529944)

Aβ₄₂-induced proteasome inhibition is associated with a delayed, inverse effect on CatB activity. by Karen L. G. Farizatto (4348537)

Overexpression of cyclin D-CDK complex components rescues AR-mediated growth suppression of HPr-1AR. by Young-Chae Kim (163381)

“…<p>(A) Transient overexpression of cyclin D1 and cyclin D2 was validated by immunoblot analysis. …”

SERCA2A expression is regulated by mTORC2. by Angelika Kusch (368579)

“…<p>Rictor silencing was induced by cell transfection with rictor siRNA and then, cells were stimulated with IGF-1 for 24 hours in presence or absence of E2. mTORC2 downregulation was confirmed by abolished Akt-pS473 and resulted in decreased SERCA2A protein expression. Akt-pT308, mTOR and raptor were not negatively affected by rictor silencing. …”

17ß-Estradiol Regulates mTORC2 Sensitivity to Rapamycin in Adaptive Cardiac Remodeling by Angelika Kusch (368579)

“…In addition, cardiomyocytes with reduced Akt-pS473 under rapamycin treatment displayed decreased SERCA2A mRNA and protein expression suggesting negative functional consequences on cardiomyocyte contractility. …”

siRNA knockdown of TGFβ1 in NTM cells led to an increase in RASAL1 expression by Western blotting. by Fiona McDonnell (2636635)

“…This indicates that when TGFβ1 is decreased, its pathway is also affected. Further, a decrease in TGFβ1 expression by siRNA treatment also led to an increase in RASAL1 protein expression B, a decrease in COL1A1 expression C and a decrease in DNMT1 expression D. …”

IL-17A, a possible biomarker for the evaluation of treatment response in <i>Trypanosoma cruzi</i> infected children: A 12-months follow-up study in Bolivia by Clara Vásquez Velásquez (7429844)

“…</p><p>Within 14 Th1/Th2/Th17 cytokines, IL-17A showed significantly higher levels in seropositive children before the treatment compared to age-matched seronegative children and significantly decreased to the normal level one-year after. …”

Body distribution of <i>P</i>. <i>mirabilis</i> in tumor-bearing mice. by Hong Zhang (25820)

“…<p>(A) The bacteria were detected in tumors and other organs, including heart, liver, spleen, lung and kidney at 0, 6, 24, 48, 72, and 96 hours after <i>P</i>. …”

Predicted acceptance probabilities to a top 5 journal against Alma mater ranking at the time of graduation using splines. by Sergey V. Popov (6719075)

Overexpression of pyruvate dehydrogenase kinase 1 in retinoblastoma: A potential therapeutic opportunity for targeting vitreous seeds and hypoxic regions by Swatishree Sradhanjali (4025933)

“…In this study, we have evaluated the expression of PDK1 in RB clinical samples, and studied its inhibition as a strategy to decrease cell growth and migration. …”

Uncropped Nemp1, Ter119, and Histone3 immunoblots with boxed area used to build Fig 3A. by Didier Hodzic (132944)

Insect performance on seven different alfalfa cultivars and a two-way choice assay on Zhongmu-1 and Xinjiang Daye. by Yunting Lei (4256269)

The therapeutic effect of <i>P</i>. <i>mirabilis</i> in 4T1 solid tumor model. by Hong Zhang (25820)

“…<p>(A) Bacterial treatment suppressed tumor growth at the end of the experiment. …”

Model for AR-mediated growth suppression of HPr-1AR and PC3-Lenti-AR. by Young-Chae Kim (163381)

“…(B) Androgen signaling through AR increases CDKN1A expression and decreases the abundance and activity of cyclin D-CDK4/6 complexes by multiple mechanisms. …”

Discrimination between Adenocarcinoma and Normal Pancreatic Ductal Fluid by Proteomic and Glycomic Analysis by Mindy Porterfield (1849300)

“…Our results identify a set of seven proteins that were consistently increased in cancer ductal fluid compared to normal (AMYP, PRSS1, GP2-1, CCDC132, REG1A, REG1B, and REG3A) and one protein that was consistently decreased (LIPR2). …”

Inhibition of FleA by 2EHex or fucose results in a loss of mucin binding and greatly reduced phagocytosis by macrophages. by Sheena C. Kerr (495450)

“…Removing the double bond or extending the carbon chain beyond 6 carbons (hexyl α-L-fucopyranoside, (2E)-octenyl α-L-fucopyranoside) markedly decreases inhibition. (2E)-hexenyl α-D-galactopyranoside has no effect on FleA binding to mucin. …”

Association of the G473A Polymorphism and Expression of Lysyl Oxidase with Breast Cancer Risk and Survival in European Women: A Hospital-Based Case-Control Study by Andrea Friesenhengst (618739)

“…We found that the minor A-allele of this polymorphism is associated with a later age at breast cancer onset, a trend towards a decreased disease-free and metastasis-free survival, but not with an increased breast cancer risk. …”

FBG1 knockout increases A1AT-Z dPAS accumulation in the mouse liver. by John H. Wen (785980)

Knockdown of FBG1 in HepG2 cells increases levels of endogenous A1AT. by John H. Wen (785980)

Image_2_Simultaneous targeting of Tim3 and A2a receptors modulates MSLN-CAR T cell antitumor function in a human cervical tumor xenograft model.jpeg by Tahereh Soltantoyeh (15944541)

“…To overcome this challenge, researchers have investigated the potential of inhibiting specific immune checkpoint receptors, including A2aR (Adenosine A2 Receptor) and Tim3 (T cell immunoglobulin and mucin domain-containing protein 3), to enhance CAR T cell function. …”