A Peptide Mimetic of 5-Acetylneuraminic Acid-Galactose Binds with High Avidity to Siglecs and NKG2D by Laura L. Eggink (760403)

“…Using plant lectins as analogs of lectin-type cell-surface receptors, a tetravalent form of a peptide with the sequence NPSHPLSG, designated svH1C, bound with high avidity to lectins specific for glycans with terminal 5-acetylneuraminic acid (Neu5Ac)-galactose (Gal)/N-acetylgalactosamine (GalNAc) sequences. …”

Image_1_Simultaneous targeting of Tim3 and A2a receptors modulates MSLN-CAR T cell antitumor function in a human cervical tumor xenograft model.jpeg by Tahereh Soltantoyeh (15944541)

“…To overcome this challenge, researchers have investigated the potential of inhibiting specific immune checkpoint receptors, including A2aR (Adenosine A2 Receptor) and Tim3 (T cell immunoglobulin and mucin domain-containing protein 3), to enhance CAR T cell function. …”

Image_5_Simultaneous targeting of Tim3 and A2a receptors modulates MSLN-CAR T cell antitumor function in a human cervical tumor xenograft model.jpeg by Tahereh Soltantoyeh (15944541)

“…To overcome this challenge, researchers have investigated the potential of inhibiting specific immune checkpoint receptors, including A2aR (Adenosine A2 Receptor) and Tim3 (T cell immunoglobulin and mucin domain-containing protein 3), to enhance CAR T cell function. …”

Image_4_Simultaneous targeting of Tim3 and A2a receptors modulates MSLN-CAR T cell antitumor function in a human cervical tumor xenograft model.jpeg by Tahereh Soltantoyeh (15944541)

“…To overcome this challenge, researchers have investigated the potential of inhibiting specific immune checkpoint receptors, including A2aR (Adenosine A2 Receptor) and Tim3 (T cell immunoglobulin and mucin domain-containing protein 3), to enhance CAR T cell function. …”

Image_3_Simultaneous targeting of Tim3 and A2a receptors modulates MSLN-CAR T cell antitumor function in a human cervical tumor xenograft model.jpeg by Tahereh Soltantoyeh (15944541)

“…To overcome this challenge, researchers have investigated the potential of inhibiting specific immune checkpoint receptors, including A2aR (Adenosine A2 Receptor) and Tim3 (T cell immunoglobulin and mucin domain-containing protein 3), to enhance CAR T cell function. …”

A schematic representation of mechanisms of TMP for AS. by SiJin Li (12488187)

PCoA analysis of fungal communities. by Yumei Liang (8661069)

Design of a RSSCA system for agriculture. by Ngoc-Hai Vu (22290844)

“…<div><p>Agricultural land is increasingly under pressure from expanding solar energy infrastructure, leading to a growing conflict between food and energy production. …”

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…</p> <p>Results — Compared with the reference cohort, a distinctly larger proportion of the OA cohort had dispensed prescriptions for most types of analgesics, increasing exponentially each year prior to commencing non-pharmacological intervention. …”

Adult female tree crickets <i>Oecanthus nigricornis</i> with <i>a)</i> few ovarian eggs and <i>b)</i> an abdomen full of ovarian eggs; <i>c)</i> Predaceous wasp <i>Isodontia mexica... by Kyla Ercit (645474)

A diagram summarizes how high-salt diet (HSD) altered the intestinal morphology and the expression of calcium transporters, namely TRPV6 and PMCA₁. by Natchayaporn Thonapan (14142010)

“…An arrow with a dashed line indicates a hypothetical mechanism. …”

Visualization of quantitative variables (a) and individuals (b) from a Multiple Factor Analysis (MFA) describing the relationship between support for conservation, individual, and... by Thaïs A. Bernos (3193842)

“…<p>On Fig 4A, Individual attributes (IN) include age (young/old), gender (woman/man), association membership (asso/noasso), attachment to fishing (att/noatt), dependence on fisheries (dep/nodep); perceptions related to ecological degradation (ED) include distance to fishing sites (dist/nodist), fish size (size/nosize), fish numbers (num/nonum), and local disapearance (disp/nodisp); perceptions related to underling causes (Co) associated with local fishing (fish/nofish); local assets (LA) include shops (sho/no), hotels (hot/nohot), leisures (leis/noleis), and lagoons (lag/nolag); coping mechanisms include realized (CR) to observed changes (continue/decrease/adapt) and hypothetical (CH) to further changes (continue/decrease/adapt). …”

The change in the patch-specific proportion of infected hosts in a high transmission patch (<i>R</i>_0,<i>i</i> = 3.6) and a low transmission patch (<i>R</i><sub>0,<i>i</... by Miguel A. Acevedo (381283)

siRNA oligonucleotide specific for PKA causes decreased expression and activity of PKA and ameliorated the high glucose mediated decrease of G6PD activity. by Zhaoyun Zhang (118032)

“…Figures A and B show that siRNA led to decreased expression and decreased activity of PKA. …”

A good net tucked under a mattress on the floor strained to window grills and hand forged door metal lock; 2 - A torn net offering no maximum protection. by Job Oyweri (22041452)

Image_1_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_5_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_3_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.tif by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_6_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”

Image_2_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We further investigated the MLN DCs, and a significant decrease in RALDH2 gene expression was observed in MLN DCs from aged mice. …”