Image_4_CD209/CD14+ Dendritic Cells Characterization in Rheumatoid and Psoriatic Arthritis Patients: Activation, Synovial Infiltration, and Therapeutic Targeting.tif by Viviana Marzaioli (3484127)

“…Furthermore, we demonstrated that JAK/STAT inhibition can be used as a therapeutic strategy to decrease the inflammatory state of the pathogenic CD209/CD14⁺ DC.…”

Low- and High-Volume of Intensive Endurance Training Significantly Improves Maximal Oxygen Uptake after 10-Weeks of Training in Healthy Men by Arnt Erik Tjønna (416233)

“…Both groups had a similar ∼5% decrease in fasting glucose. Body fat, total cholesterol, LDL-cholesterol, and ox-LDL cholesterol only were significantly reduced after 4-AIT. …”

Image1_Skeletal Muscle Adaptations to Exercise Training in Young and Aged Horses.TIF by Christine M. Latham (11611039)

“…<p>In aged humans, low-intensity exercise increases mitochondrial density, function and oxidative capacity, decreases the prevalence of hybrid fibers, and increases lean muscle mass, but these adaptations have not been studied in aged horses. …”

The cKO mice make more entries in the food receptacle during reinstatement. by Robert Fredriksson (27811)

“…On the FR2 and FR3 schedule the cKO mice nose pokes significantly lower number as compared to ctrl (Mann Whitney U-test p = 0.037 and p = 0.0397). C) There were a clear decrease of nose pokes in the inactive apparatus for both cKO and ctrl mice during the FR1-FR3 schedule. …”

Randomized, Controlled Trial of Therapy Interruption in Chronic HIV-1 Infection by Emmanouil Papasavvas (5406)

“…Here we present longitudinal follow-up of a randomized, open-label, single-center study of the immune, viral, and safety outcomes of structured therapy interruptions (TIs) in patients with chronically suppressed HIV-1 infection as compared to equal follow-up of patients on continuous therapy and including a final therapy interruption in both arms.…”

Table_1_Functional infrared thermography imaging can be used to assess the effectiveness of Maxicam Gel® in pre-emptively treating transient synovitis and lameness in horses.DOCX by Júlia Ribeiro Garcia de Carvalho (18804619)

“…The C group presented an increase in neutrophils and a decrease in total hemoglobin and hematocrit 8 h after induction. …”

Structural definition of the full VRC01-class bnAb epitope in the context of the Env trimer. by Joseph G. Jardine (3075186)

“…<p>(<b>A</b>) Crystal structure of eOD-N276Kif containing a Man₉GlcNAc₂ glycan at N276 in complex with VRC01, with the critical MinVRC01 mutations from germline shown as spheres and colored as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005815#ppat.1005815.g002" target="_blank">Fig 2B</a>. …”

Parasitemia titration results. by Paul Lebel (11250722)

“…The Faster R-CNN method was used to detect cells directly on the raw images (yellow). b) The data from a) were re-plotted after compensation for recall and FPR, for an array of confidence threshold values applied to the data. c) Recall and FPR compensation values are plotted as a function of confidence threshold, which both decrease with threshold value, as healthy cells’ median confidence is on the order of 99.9%. d) Manual counting of Giemsa-stained smears by three experienced technicians are plotted with solid red curves (human 1: squares, human 2: hexagrams, human 3: pentagrams), and their arithmetic mean plotted in solid black (circles). …”

Data_Sheet_1_Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies.pdf by Eli Hatchwell (8584452)

“…</p>Conclusion<p>For the first time, a PML genetic risk test can be implemented for screening patients taking or considering treatment with a PML-linked drug in order to decrease the incidence of PML and enable safer use of highly effective therapies used to treat their underlying disease.…”

DataSheet_1_Assessing risk from invasive alien plants in China: Reconstructing invasion history and estimating distribution patterns of Lolium temulentum and Aegilops tauschii.docx by Ming Yang (109148)

“…Lolium temulentum and Aegilops tauschii are critical IAPs in China because they reduce the quality of cereal grains and decrease wheat yields. Lolium temulentum is a winter-temperate weed that spreads easily and is poisonous to humans and animals. …”

In Vitro Inhibition of NFAT5-Mediated Induction of CCL2 in Hyperosmotic Conditions by Cyclosporine and Dexamethasone on Human HeLa-Modified Conjunctiva-Derived Cells by Elise Warcoin (3144120)

“…Adding NFAT5-siRNA before hyperosmolar stimulation led to a complete inhibition of CCL2 induction and to a decrease in cellular viability. p38 MAPK (p38), c-Jun NH₂-terminal kinase (JNK) and NFĸB inhibitors, CsA and Dex induced a partial inhibition of HO-induced CCL2, while Dox and extracellular signal-regulated kinase (ERK) inhibitor did not. …”

Experimental procedure and results of Experiment 1. by İlayda Nazlı (19332772)

“…<p><i>Note</i>. (A) Experiment 1 comprised two training phases (training phase 1 and training phase 2) and a test phase. …”

Evolution of New <i>cis</i>-Regulatory Motifs Required for Cell-Specific Gene Expression in <i>Caenorhabditis</i> by Michalis Barkoulas (3097899)

“…<i>elegans</i> results in a dramatic decrease in <i>lin-3</i> expression. …”

Hexokinase 2 (Hxk2) is the main 2DG-phosphorylating enzyme <i>in vivo</i>. by Clotilde Laussel (13237429)

“…Values are normalized to the value of the WT / 15 min (n = 3 independent experiments ± SEM, <i>p</i>value indicated, paired <i>t</i>-test) (<b>B</b>) 2DG causes a decrease in ATP content as visualized using a FRET ATP biosensor. …”

Integrated NMR interface and mutagenesis data illustrated onto the HPV16 E6 3D structure. by Katia Zanier (17371)

“…Side-chains that when mutated decrease E6/pep11** binding in mammalian two-hybrid assays by 1.5-fold or more (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0112514#pone-0112514-g005" target="_blank">Figure 5C</a>) are displayed.…”

Interface Engineering Modulation Combined with Electronic Structure Modification of Zn-Doped NiO Heterostructure for Efficient Water-Splitting Activity by Gundegowda Kalligowdanadoddi Kiran (17654768)

“…Also, the results obtained from density functional theory (DFT + <i>U</i> = 0–8 eV), where <i>U</i> is the on-site Coulomb repulsion parameter also known as Hubbard <i>U</i>, based electronic structure calculations confirm that Zn doping constructively modifies the electronic structure, in both the valence band and the conduction band, and found to be suitable in tailoring the carrier’s effective masses of electrons and holes. The decrease in electron’s effective masses together with large differences between the effective masses of electrons and holes is noticed, which is found to be mainly responsible for achieving the best water-splitting performance from a 9% Zn-doped NiO sample prepared under vacuum.…”

Reversal of GABAergic postsynaptic currents by the ANO2 inhibitor. by Weiping Zhang (311523)

“…Application of the ANO2 inhibitor <i>(lower scheme)</i> reduces the Cl^- conductance. This causes a polarity reversal of the Cl^- driving force, as the balance shifts towards Cl^- extrusion, causing local [Cl^-]_i to decrease. …”

Microglial process dynamics and injury-induced process recruitment are altered by bumetanide. by Krisztina Tóth (12009827)

“…(<b>E)</b> Calculated postlesion velocities of microglial process recruitment using automated image analysis followed by model fitting. Data show a significant decrease (31.7%) in mean frontline velocity of cells with Bum administration. …”

Metal−Metal Bonding and Correlated Metallic Behavior in the New Deficient Spinel Ga_0.87Ti₄S₈ by C. Vaju (2447485)

“…We have synthesized and characterized the first Ti member of the AM₄X₈ (A = Ga, Ge; M = V, Nb, Ta, Mo, X = S, Se) family of compounds that exhibit a deficient spinel structure with tetrahedral transition metal clusters. …”

Synthesis and Evaluation of Novel Substrates and Inhibitors of <i>N-</i>Succinyl-ll-diaminopimelate Aminotransferase (DAP-AT) from <i>Escherichia coli</i> by Russell J. Cox (225848)

“…Progress of the reaction is monitored by spectrophotometric observation of decrease in NADPH concentration at 340 nm in a coupled enzyme assay with l-glutamate dehydrogenase (EC 1.4.1.4). …”