Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…We confirmed experimentally that the interaction is predominantly driven by electrostatic forces, and using noncanonical amino acids as photo-cross-linkers, we identified 16 residues in ASIC1a contributing to Big Dyn binding. Covalently tethering Big Dyn to its ASIC1a binding site dramatically decreased the proton sensitivity of channel activation, suggesting that Big Dyn stabilizes a resting conformation of ASIC1a and dissociates from its binding site during channel opening.…”

Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…We confirmed experimentally that the interaction is predominantly driven by electrostatic forces, and using noncanonical amino acids as photo-cross-linkers, we identified 16 residues in ASIC1a contributing to Big Dyn binding. Covalently tethering Big Dyn to its ASIC1a binding site dramatically decreased the proton sensitivity of channel activation, suggesting that Big Dyn stabilizes a resting conformation of ASIC1a and dissociates from its binding site during channel opening.…”

GluN2A(D731N) decreases current amplitudes and shortens synaptic-like response time course. by Kai Gao (120150)

Subjects:

Decreased activity of FASII favors the cold growth of the <i>ΔcshA</i> strain. by Vanessa Khemici (814639)

“…<p><b>(A)</b><i>fapR</i> mRNA levels decrease in ACC and biotin related suppressor strains. …”

Cryo-electron tomography of a FC reveals linear, periodical protein arrangements in the interstitial zone. by Johanna L. Höög (402710)

“…<p><b>A)</b> An overview of the cryo-section shows the old flagellum, new flagellum tip and the cell body sectioned transversally to the cells longitudinal axis. …”

Optimal allocation of clusters and efficiency of uniform allocation in a cohort design. by Mirjam Moerbeek (8603520)

JNK inhibitor AS601245 decreased levels of Bim and CC3 proteins and reduced neuronal apoptosis and brain infarct volume in P7 rat after HI. by Deyuan Li (769599)

“…The infarct volume in the AS601245-treated brain was decreased by 58% compared with the DMSO controls (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132998#pone.0132998.g004" target="_blank">Fig 4I</a>).…”

Assays of TUNEL revealed a decreased number of apoptotic cell after oroxylin A treatment. by Shu-Fang Lin (4167091)

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

An Experimental Investigation of Evaporation of Ethanol–Water Droplets Laden with Alumina Nanoparticles on a Critically Inclined Heated Substrate by Pallavi Katre (10796035)

“…The pinning effect caused by nanoparticles results in a larger perimeter and surface area for the nanoparticle-laden droplets, enhancing the evaporation rates and significantly decreasing the lifetime of the nanoparticle-containing droplets compared to the no-loading case. …”

Table_2_Antiretroviral Treatment-Induced Decrease in Immune Activation Contributes to Reduced Susceptibility to Tuberculosis in HIV-1/Mtb Co-infected Persons.xlsx by Katalin A. Wilkinson (10193231)

“…Next, we evaluated 30 soluble analytes in QuantiFERON Gold in-tube (QFT) samples from the Ag stimulated and Nil tubes, during the first 6 months of ART in 30 patients. There was a significant decrease in IL-1alpha and IL-1beta (Ag-Nil) concentrations as well as MCP-1 (Nil), supporting decreased immune activation and inflammation. …”

(a) Dependence of δ on η with κ = 2.0 by Shu-Wei Song (557396)

“…As the spin–orbit coupling strength gets larger and larger, the spatial displacement decreases at a rate inversely proportional to the spin–orbit coupling strength. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…Maternal peripheral leukocytes can be used to monitor a variety of physiological processes occurring in the body. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…Maternal peripheral leukocytes can be used to monitor a variety of physiological processes occurring in the body. …”

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)

Multiple linear regression models of fetal NT and plasma trace element levels in primiparas and multiparas. by Kai-Wei Liao (620360)

Within-race sex disparities in COVID-19 incidence and mortality. by Max Jordan Nguemeni Tiako (11442284)

Summary of regression results. by Max Jordan Nguemeni Tiako (11442284)

“…Black-White disparities decreased over time, with a larger effect on Black men, and Older Black people were particularly more vulnerable to COVID-19 in terms of mortality. …”