The first dipeptidyl peptidase III from a thermophile: Structural basis for thermal stability and reduced activity by Igor Sabljić (2807347)

“…<div><p>Dipeptidyl peptidase III (DPP III) isolated from the thermophilic bacteria <i>Caldithrix abyssi</i> (<i>Ca</i>) is a two-domain zinc exopeptidase, a member of the M49 family. …”

Impact of Etiology on the Outcomes in Heart Failure Patients Treated with Cardiac Resynchronization Therapy: A Meta-Analysis by Yanmei Chen (114960)

“…In the pooled analysis of observational studies, however, we found that ICM patients had a 54% greater risk for mortality or HF hospitalization than NICM patients (relative risk: 1.54; 95% CI: 1.30–1.83; P<0.001). …”

Data_Sheet_1_Stuttering in individuals with Down syndrome: a systematic review of earlier research.pdf by Silje Hokstad (10577739)

“…We identified 14 eligible studies, with a total of 1,833 participants (mean = 131.29, standard deviation = 227.85, median = 45.5) between 3 and 58 years of age. …”

Table_1_The Development of Evidence-Based Classification of Vision Impairment in Judo: A Delphi Study.DOCX by Kai J. Krabben (6338663)

“…</p><p>Results: The panel expressed that: (i) blind and partially sighted athletes should not compete against each other in the same class; (ii) additional measures of visual function might be needed to accurately evaluate an athlete’s impairment; (iii) the minimum impairment criteria (MIC) should represent a more severe level of impairment to ensure that all those included possess a level of VI that indeed decreases performance in judo; and (iv) legitimate competition could be undermined by some athletes intentionally underperforming on classification tests. …”

Image_1_Baicalein—A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury.jpeg by Li Pan (49390)

“…<p>Retinal ischemia is a common cause of many retinal diseases, leading to irreversible vision impairment and blindness. …”

Image_2_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF by Lingling Lu (2589835)

“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”

Spatial variations of soil respiration and temperature sensitivity along a steep slope of the semiarid Loess Plateau by Qiqi Sun (785068)

“…<div><p>The spatial heterogeneity of soil respiration and its temperature sensitivity pose a great challenge to accurately estimate the carbon flux in global carbon cycling, which has primarily been researched in flatlands versus hillslope ecosystems. …”

Image1_The light-independent locomotion response to a static magnetic field in Xenopus tadpoles.TIF by Jie Ren (176083)

“…We have previously reported that the physical performance of mice decreased after 1 month of exposure to a hypomagnetic field, which probably includes a light-independent mechanism. …”

An AlphaFold2-based variant effect classification scheme for the CXXC domain of KMT2A. by Tinna Reynisdottir (12902681)

“…The surface of the domain is color-coded based on the electrostatic potential, with red indicating a negative charge and blue a positive charge. Both variants lead to a decreased electrostatic potential in a residue important for DNA binding.…”

Sirtuin 1 Regulates SREBP-1c Expression in a LXR-Dependent Manner in Skeletal Muscle by Aurélia Defour (135815)

“…<div><p>Sirtuin 1 (SIRT1), a NAD⁺-dependent protein deacetylase, has emerged as a main determinant of whole body homeostasis in mammals by regulating a large spectrum of transcriptional regulators in metabolically relevant tissue such as liver, adipose tissue and skeletal muscle. …”

Defect-Induced Band-Edge Reconstruction of a Bismuth-Halide Double Perovskite for Visible-Light Absorption by Adam H. Slavney (1415035)

“…The first halide double perovskite evaluated as an absorber, Cs₂AgBiBr₆ (<b>1</b>), has a bandgap of 1.95 eV. Here, we show that dilute alloying decreases <b>1</b>’s bandgap by ca. 0.5 eV. …”

Table_1_Exploring the role of gut microbiota dysbiosis in gout pathogenesis: a systematic review.DOCX by Salman Shirvani-Rad (15535610)

“…This systematic review aimed to summarize the role of gut dysbiosis in gout disease and uncover the underlying mechanisms.</p>Methods<p>A comprehensive search was conducted on PubMed, Web of Science, and Scopus databases up to October 2021. …”

Evolutionary history predicts the response of tree species to forest loss: A case study in peninsular Spain by Rafael Molina-Venegas (3300951)

“…However, the probability of occurrence of many species increased when forest canopy cover decreased across landscape scales. We detected a strong phylogenetic signal in species response to forest loss at local and small landscape (1.6 km) scales. …”

Image_4_Circulating fatty acids, genetic susceptibility and hypertension: a prospective cohort study.PDF by Lingling Lu (2589835)

“…Background<p>Combining genetic risk factors and plasma fatty acids (FAs) can be used as an effective method of precision medicine to prevent hypertension risk.</p>Methods<p>A total of 195,250 participants in the UK Biobank cohort were included in this study from 2006–2010. …”

Table_1_Identification and Characterization of Circular RNA as a Novel Regulator and Biomarker in Preterm Birth.DOCX by Yuxin Ran (7729352)

“…<p>Preterm birth (PTB), as the leading cause of neonatal death, is a severe threat to maternal–fetal health. The diagnosis and treatment of PTB are difficult as its underlying mechanism still unknown. …”

Impaired bone formation in <i>Col1a1-Krm2</i> transgenic mice. by Jochen Schulze (365258)

“…(B) Histomorphometric quantification showing that the number of osteoblasts (ObN/BPm, osteoblast number per bone perimeter) is not significantly decreased in sections from transgenic mice. (C) Fluorescent micrographs showing that overall calcein labeling is reduced in vertebral bodies of 6 weeks old female <i>Col1a1-Krm2</i> transgenic mice (top, scale bars, 1 mm), as is the distance between the labeled surfaces at endosteal bone surfaces of the tibia (bottom, scale bars, 20 µm). …”

Table 1_Kinesiophobia in patients with coronary heart disease: a Rodgers’ evolutionary concept analysis.docx by Mei-Jun Zhang (3185463)

“…</p>Methodology<p>Rodgers’ evolutionary concept analysis method was applied to review the literature. A comprehensive search was conducted in PubMed, Web of Science, PsycINFO, CINAHL, Cochrane Library, Embase, Scopus, ProQuest, OVID, CNKI, Wanfang Data, CBM, and VIP Database (up to June 30, 2024). …”

Regulation of <i>Cxcl12</i> promoter activity in pancreatic beta cells: a working model. by Jelena Marković (5654275)

“…<p>(A) In the basal state, non-automodified PARP-1 (acting as a transcriptional inhibitor) and YY1 (acting as a transcriptional activator) strongly bind to the <i>Cxcl12</i> promoter, enabling its transcription (Fig. 3, 4). …”

Image_2_Vulnerability of Demersal Fish Assemblages to Trawling Activities: A Traits-Based Index.TIFF by Silvia de Juan (418494)

“…In fine mud in the shallower areas there was a higher presence of low vulnerable fauna. Furthermore, vulnerable organisms decreased in their presence in sandier substrates on the continental shelf. …”

Video_2_Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model.MOV by Ravikanth Velagapudi (7880072)

“…<p>Postoperative delirium is a frequent and debilitating complication, especially amongst high risk procedures such as orthopedic surgery, and its pathogenesis remains unclear. …”