S3 Fig - by R. J. S. D. Heine (17889199)

“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”

S6 Fig - by R. J. S. D. Heine (17889199)

“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”

Input parameters for the base-case analysis. by R. J. S. D. Heine (17889199)

“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”

S2 Fig - by R. J. S. D. Heine (17889199)

“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”

S1 Data - by R. J. S. D. Heine (17889199)

“…</p><p>Methods</p><p>The model was used to calculate cumulative yearly prices, cumulative prices per indication, and non-cumulative indication-based prices using inputs such as research and development (R&D) costs, manufacturing costs, eligible patient population, and a profit margin. A deterministic stepwise analysis and scenario analysis were conducted to examine how sensitive the estimated price is to the different input assumptions.…”

High levels of IFNγ partially restores <i>C</i>. <i>trachomatis</i> development in HeLa cells. by Shardulendra P. Sherchand (3133677)

“…As reported previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0163174#pone.0163174.ref019" target="_blank">19</a>], the addition of 300 U/mL IFNγ resulted in a statistically significant 2-log decrease in IFU recovery. …”

Time evolution of patient outcomes for a range of neutrophil (<i>N</i>) and cortisol (<i>C</i>) initial conditions for model (1). by Manuel Mai (497861)

Interhomolog polymorphism shapes meiotic crossover within the Arabidopsis <i>RAC1</i> and <i>RPP13</i> disease resistance genes by Heïdi Serra (488603)

“…We mapped crossover hotspots located in the <i>Arabidopsis thaliana RAC1</i> and <i>RPP13</i> disease resistance genes, using varying haplotypic combinations. We observed a negative non-linear relationship between interhomolog divergence and crossover frequency within the hotspots, consistent with polymorphism locally suppressing crossover repair of DSBs. …”

Accumulation of glutamine and glutamate in <i>L. tarentolae</i> WT and A150.1. by Gaétan Roy (187604)

Histology of miR-181a1/b1^-/- (a/b KO) and control (WT). by Daijiro Hori (3850915)

Subjects:

A novel <i>FLNC</i> frameshift and an <i>OBSCN</i> variant in a family with distal muscular dystrophy by Daniela Rossi (1716643)

“…<div><p>A novel <i>FLNC</i> c.5161delG (p.Gly1722ValfsTer61) mutation was identified in two members of a French family affected by distal myopathy and in one healthy relative. …”

Principal Coordinates Analysis (PCoA) of gut bacterial (A) and fungal (B) communities in <i>C. capitata.</i> by Maria Cecilia Rasuk (4594303)

Comparison of community composition of phyllosphere bacteria (a, c, e) and fungi (b, d, f) at species (a, b), function (b, d) and phylogenetic (e, f) levels between the control and... by Zhiming Zhong (1745548)

HbA1c, plasma glucose and plasma insulin levels in the chronic treatment study. by Yoshinori Tsumura (3753757)

To demonstrate aversion to bobcat urine, percent time spent in the quadrant with bobcat urine (Bobcat Urine) was compare to the percent time spent in the same quadrant from the pre... by Jeffrey B. Eells (11751583)

Genome-wide association analysis identifies multiple loci associated with kidney disease-related traits in Korean populations by Jeonghwan Lee (286889)

“…<div><p>Chronic kidney disease (CKD) is an important social health problem characterized by a decrease in the kidney glomerular filtration rate (GFR). …”

Supplementary file 1_Early life predictors of child development at kindergarten: a structural equation model using a longitudinal cohort.docx by Sarah E. Turner (8478309)

“…Higher SES was related to a-0.26 (p-value =0.01) standardized decrease of EDI vulnerability, and this link was partially mediated through family stress at 3 years (10.6% mediated). …”

Table4_Eight weeks of dry dynamic breath-hold training results in larger spleen volume but does not increase haemoglobin concentration.XLSX by Kun Yang (19445)

“…Spleen sizes were measured with an ultrasound system and a complete blood cell analysis was performed on the median cubital venous blood.…”

Table1_Eight weeks of dry dynamic breath-hold training results in larger spleen volume but does not increase haemoglobin concentration.XLSX by Kun Yang (19445)

“…Spleen sizes were measured with an ultrasound system and a complete blood cell analysis was performed on the median cubital venous blood.…”

Table2_Eight weeks of dry dynamic breath-hold training results in larger spleen volume but does not increase haemoglobin concentration.XLSX by Kun Yang (19445)

“…Spleen sizes were measured with an ultrasound system and a complete blood cell analysis was performed on the median cubital venous blood.…”