High ELS participants exhibited lower positive feedback sensitivity than those without a history of ELS. by Matthew Paul Wilkinson (11824625)

X‑ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson’s Disease Mouse Model by Jun Mou (4113313)

“…In a MPTP-induced Parkinson’s disease (PD) mouse model, <b>BI-43</b> manifested efficacy in mitigating locomotor deficits through reversing dopaminergic neuronal loss, reducing microglia, and decreasing levels of the sQC/gQC substrates, α-synuclein, and CCL2. …”

Box plot of queens and males in the young colony (left) and old colony (right) A-B compares the queens and males distribution in the young and old colonies, respectively. by Moïse Pierre Exélis (21578515)

Architecture of early-combined model (Model (A)). by Wanchalerm Pora (8360934)

A block of diagram of the process of our method. by Shuting Liao (9524506)

Raw data as basis for a meta-analysis. by Chan Guo (6116351)

A visual summary of the key study findings. by Joachim Worthington (8394213)

“…These changes would lead to an estimated increase of 255 colorectal cancer cases and 1,820 colorectal cancer deaths in Canada and 234 cases and 1,186 deaths in Australia over 2020–2030; a 1.9% and 2.4% increase in mortality, respectively, vs a scenario with no screening disruption or diagnostic/treatment delays. …”

A: Reduced image; B: Focal area. by Shuting Liao (9524506)

Cinnamaldehyde is a specific ligand for HL-IR. by Ceyan Kuang (8554557)

“…The ratio of bound/free 1-NPN gradually decreased as the concentration of 1-NPN increased, accompanied by a corresponding rise in fluorescence intensity. …”

Total inhibitory input as a function of figure size. by Hans Supèr (285410)

“…<p><b>A</b>: The total amount of inhibitory input that a neuron receives increases for larger figures for neurons located on the figure. …”

The Efficacy of Taurolidine Lock Solution in Preventing Catheter-Related Bloodstream Infections in Pediatrics: A Systematic Review and Meta-Analysis by Congyu Qin (22386781)

Motor Adaptations to Pain during a Bilateral Plantarflexion Task: Does the Cost of Using the Non-Painful Limb Matter? by François Hug (290603)

“…This decrease in force was correlated with a decrease in drive to the soleus muscle. …”

Evolution of the four pre-stimuli psychological parameters (A: Valence, B: Arousal, C: Tension, D: Energy). by Felix Alexandre Schoeller (20988295)

Quiescent amastigotes exhibit a significantly reduced size compared to DsRed^hi amastigotes. by Laura Dirkx (8950205)

PK profiles of the developed nanoparticles vs. free drugs in rats (a) amlodipine, (b) hydrochlorothiazide, and (c) candesartan. by Anjuman Arora (750291)

A. Bar chart showing the percentage of participants experiencing chills in response to various stimuli, ordered by descending frequency. by Felix Alexandre Schoeller (20988295)

“…<p>B: Line graph indicating a decrease in the chills ratio over successive presentations of stimuli, with a marked drop between the fifth and sixth exposure. …”

Attenuation of CDK expression and cyclin D-CDK4/6 activity by androgen in HPr-1AR. by Young-Chae Kim (163381)

“…Immunoblot analysis of cell lysates reveals that CDK4 and CDK6 protein expression decreased and CDKN1A expression increased with DHT treatment compared to vehicle. …”

AR-mediated transcriptional regulation of cyclin D2, CDK4/6, and CDKN1A pre-mRNAs in HPr-1AR. by Young-Chae Kim (163381)

“…<p>(A) Depiction of QPCR amplicons that were designed to detect various regions of cyclin D1 pre-mRNA and mRNA. …”

Attenuation of CDK expression and cyclin D-CDK4/6 activity by androgen in PC3-Lenti-AR. by Young-Chae Kim (163381)

“…(E) In comparison to control samples, DHT treatment for 24 hours significantly decreased CDK4 and CDK6 mRNAs and pre-mRNAs 1.5 fold or more and increased CDKN1A mRNA and pre-mRNA 2 fold or more, suggesting AR-mediated regulation of transcription at these genes, n = 3. …”

Inhibition of PC3-Lenti-AR cell proliferation in response to androgen. by Young-Chae Kim (163381)

“…(D) In time course experiments, PC3-Lenti-AR cells proliferated in the presence of DHT, albeit at a decreased rate. In comparison to control-treated PC3-Lenti-AR cells, 24%, 36%, and 63% fewer PC3-Lenti-AR cells were present following treatment with DHT for 3, 4, and 6 days (72, 96, and 144 hours), respectively. …”