The UBR-1 ubiquitin ligase regulates glutamate metabolism to generate coordinated motor pattern in <i>Caenorhabditis elegans</i> by Jyothsna Chitturi (5094419)

“…<i>elegans</i> UBR-1 leads to a specific motor deficit: when adult animals generate reversal movements, A-class motor neurons exhibit synchronized activation, preventing body bending. …”

Table_1_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp... by Wang Zhang (289732)

“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”

Image_4_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp... by Wang Zhang (289732)

“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”

Image_1_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp... by Wang Zhang (289732)

“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”

Image_4_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp... by Wang Zhang (289732)

“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”

Table_1_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp... by Wang Zhang (289732)

“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”

Image_1_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp... by Wang Zhang (289732)

“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”

Image_2_Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymp... by Wang Zhang (289732)

“…Clinical improvement was accompanied by a reducing IgA secreted by the intestine and a decreasing IgA + B220 + lymphocytes in Peyer’s patches. …”

SOCE inhibitors affected fibrosis markers and cell morphology in SSc fibroblasts. by Ching-Ying Wu (3145974)

“…<p>After treatment with SOCE inhibitors for 24 h, (A) analysis of the expression of TGF-β1, fibronectin, α-SMA, β-actin, α-tubulin and GAPDH in three groups. …”

DataSheet_1_T-regulatory cells require Sin3a for stable expression of Foxp3.pdf by Lanette M. Christensen (6890030)

“…Mice also showed effector T-cell activation, autoantibody production, and widespread tissue injury. Mechanistically, Sin3a deletion resulted in decreased transcription of Foxp3 with a complete lack of CNS2 CpG demethylation. …”

Effect of genistein treatment and expression of HOTAIR and miR-34a in PCa cells. by Takeshi Chiyomaru (140914)

“…<p>(A) Expression of HOTAIR in PCa cell lines (LNCaP, PC3 and DU145) and normal prostate epithelial cells (RWPE-1). …”

Image_1_A Novel α-Galactosidase A Splicing Mutation Predisposes to Fabry Disease.pdf by Ping Li (31981)

“…<p>Fabry disease (FD) is a rare X-linked α-galactosidase A (GLA) deficiency, resulting in progressive lysosomal accumulation of globotriaosylceramide (Gb3) in a variety of cell types. …”

Knockdown of E2A promotes colon cancer cell growth. by Ao Huang (508797)

“…Co-transfected cells showed decreased cell proliferation rate than that of the parental or vector control (SW480/shE2A_VC, Caco-2/shE2A_VC) transfected cells. …”

The expression of Cregs is diminished in the allograft model with the progression of ATCMR. by Kazuaki Yamanaka (2541484)

“…(B) The arrow head and the arrow indicate Crry-positive and Crry-negative glomeruli [Magnification: (a) and (b) X400, (c) ~ (h) X200]. Crry was not expressed in renal tubules. …”

Inkjet Nanoinjection for High-Thoughput Chemiluminescence Immunoassay on Multicapillary Glass Plate by Fengming Chen (1928389)

“…The analysis time and reagent consumption were significantly decreased. The IgA concentrations in saliva samples were determined after 10000-fold dilution by the developed ELISA system showing comparable results by conventional immune assay with 96-wells. …”

DataSheet_1_Maternal siRNA silencing of placental SAA2 mitigates preterm birth following intrauterine inflammation.pdf by Yang Liu (4829)

“…<p>The placental inflammatory processes induced maternally result in preterm birth (PTB). Serum amyloid A (SAA) is a well-known biomarker of inflammation. …”

Inkjet Nanoinjection for High-Thoughput Chemiluminescence Immunoassay on Multicapillary Glass Plate by Fengming Chen (1928389)

“…The analysis time and reagent consumption were significantly decreased. The IgA concentrations in saliva samples were determined after 10000-fold dilution by the developed ELISA system showing comparable results by conventional immune assay with 96-wells. …”

Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension by Tetsuo Asaki (1366140)

“…Metabolic stability and agonist potency were optimized through modification of the linear side chain. Compound <b>12b</b> (MRE-269, ACT-333679) was identified as a potent and highly selective prostacyclin receptor agonist. …”

Selexipag: An Oral and Selective IP Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension by Tetsuo Asaki (1366140)

“…Metabolic stability and agonist potency were optimized through modification of the linear side chain. Compound <b>12b</b> (MRE-269, ACT-333679) was identified as a potent and highly selective prostacyclin receptor agonist. …”

Data_Sheet_1_Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet.docx by Guangshan Zhao (8828441)

“…<p>Resveratrol (RES) is considered to be an activator of AMP-activated protein kinase (AMPK) with many reported health benefits. Polydatin (POD) is a natural precursor and glycosylated form of RES. …”