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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search), marked decrease (Expand Search)
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48501
Evidence and potential mechanisms of traditional Chinese medicine for the treatment of psoriasis vulgaris: a systematic review and meta-analysis
Published 2020“…Its pathogenesis is complex, and the multitarget effect of traditional Chinese medicine (TCM) is especially advantageous. Because a considerable number of randomized controlled trials related to TCM exhibit design defects, small sample size, or inadequate intervention time, so the status of TCM in the treatment of PV cannot be fully clarified. …”
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48502
Table_1_Effect of Alteration in Precipitation Amount on Soil Microbial Community in a Semi-Arid Grassland.DOCX
Published 2022“…<p>Climate models predict significant changes in precipitation magnitude in semi-arid grasslands, so it is vital to improve our understanding of how changing precipitation affects microbial communities in grassland ecosystems. Using a long-term field manipulation experiment, we evaluated the responses of microbial communities to a decrease (DP) and an increase (IP) in precipitation on a semi-arid grassland in northern China. …”
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48503
Knockdown of activin A increases cyclin-dependent kinase inhibitors p16, p21 and p27.
Published 2015“…<p>Cells were harvested, lysed and proteins were subjected to western blot analysis using specific antibodies against p16, p21, p27, CDK2, CDK4, CDK6, cyclin D1, cyclin E and phospho-RB. β-actin was used as loading control. A strong increase in expression of p16, p21 and p27, concomitant with decrease in phosphorylation of RB, was observed in shINHBA cells in comparison with shControl cells. …”
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48504
Unraveling the Molecular Structure of Zeolite–Octyl Methoxycinnamate Hybrid UV Filters: A Combined Spectroscopic and Computational Approach
Published 2023“…In this contribution, we tried to shed light on the molecular structure of octyl methoxycinnamate (octinoxate, OMC) adsorbed in NaX zeolite, which represents a promising hybrid UV filter system. The combination of infrared spectroscopy and density functional theory modeling was crucial to identify all the complex host–guest interactions and to unveil that, although slightly thermodynamically unfavored, OMC is dominantly present in the <i>trans-</i>form inside the NaX framework. …”
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48505
Table 1_Predicting the distribution of Sphagna (Bryophyta) in Türkiye: a perspective of present and future climate scenarios.docx
Published 2025“…Especially in the SSP5-8.5 scenario of the 2081-2100 time period, it is seen that there is a decrease in the distribution patterns of the integrals. …”
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48506
Graph depicting estimates of the fraction of the remaining tumor that is sensitive to a therapy at various times during its treatment.
Published 2014“…The graph depicts curves drawn using the median g (0.00084) and d (0.0050) values of all patients enrolled in the sunitnib arm of the study and shows: (a) the actual tumor measurements as sum of the LDs (green line); (b) the gradual decrease in the fraction of tumor that is sensitive to therapy (black line); (c) the gradual increase in the fraction of tumor relatively resistant to therapy (red line); and (d) the fraction of the remaining tumor that is still sensitive to the therapy that is being administered (blue line). …”
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48507
Proportion of narrow-sense chip heritability, <i>A</i>(<i>N</i>) (Eq 37), captured by genome-wide significant SNPs as a function of sample size, <i>N</i>, for phenotypes shown in F...
Published 2020“…Left-to-right curve order is determined by decreasing . The prediction for education at sample size N = 1.1 million is <i>A</i>(<i>N</i>) = 0.27, so that the proportion of phenotypic variance explained is predicted to be 3.5%, in good agreement with 3.2% reported in [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008612#pgen.1008612.ref070" target="_blank">70</a>]. …”
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48508
Data_Sheet_1_Altered functional connectivity and regional brain activity in a triple-network model in minimally conscious state and vegetative-state/unresponsive wakefulness syndro...
Published 2022“…These findings contribute to a better understanding of the underlying neural mechanism of functional connectivity and regional brain activity in DOC patients, and this triple-network model provides new connectivity pattern changes that may be integrated in future diagnostic tools based on the neural signatures of conscious states.…”
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48509
Table1_Stevens–Johnson syndrome induced by toripalimab in a previously EGFR-TKI-treated advanced lung adenocarcinoma patient harboring EGFR mutations 19 del/T790M/C797S in trans an...
Published 2023“…Stevens–Johnson syndrome (SJS) is a rare but potentially fatal complication of TKI and anti-PD-1 therapy. …”
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48510
DataSheet1_Trust and Psychosomatic Complaints in Adolescence: Findings From a Swedish Cohort Study.pdf
Published 2023“…</p><p>Conclusion: The findings indicate that trust is a social determinant of psychosomatic complaints in adolescents, but also that health may affect trust.…”
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48511
DataSheet_1_CircFAM114A2 Promotes Cisplatin Sensitivity via miR-222-3p/P27 and miR-146a-5p/P21 Cascades in Urothelial Carcinoma.docx
Published 2021“…</p>Results<p>We discovered that the levels of circFAM114A2 were decreased in urothelial carcinoma cell lines and tissues. …”
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48512
Safety and tolerability of HIV-1 multiantigen pDNA vaccine given with IL-12 plasmid DNA via electroporation, boosted with a recombinant vesicular stomatitis virus HIV Gag vaccine i...
Published 2018“…VSV-Gag vaccine often caused systemic reactogenicity symptoms, including a viral syndrome (in 41%) of fever, chills, malaise/fatigue, myalgia, and headache; and decreased lymphocyte counts 1 day after vaccination.…”
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48513
Corrosion inhibition of Mild Steel at Elevated temperature in highly Acidic Brines using a green corrosion inhibitor
Published 2017“…Corrosion Inhibition of mild steel in 5 M Hydrochloric acid solution at different temperatures was investigated using a new green corrosion inhibitor (lauramidopropylamine oxide). …”
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48514
Dairy Wastage Footprint Analysis: A Farm-to-Fork Life Cycle Approach Across Dairy Supply Chain.
Published 2021“…Although the dairy sector is a primary source of milk, cheese, yogurt, and cream, livestock's supply chain, including their wastes, releases a considerable greenhouse gas such as methane, nitrous oxide, and carbon dioxide. …”
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48515
NaBu- resistant MDA-MB-231 cells displayed a high tumor initiation ability in vivo.
Published 2012“…Down regulation of <i>MET</i> with a treatment of NaBu leads to decrease the tumor incident rate effectively(18%), although con siRNA teated group resulted in a similar tumor incident rate with the intact cancer cell group(83%). …”
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48516
Table_2_High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation.DOCX
Published 2019“…Dysregulation of NET production and/or degradation can exert pathogenic effects, contributing to the pathogenesis of various diseases, including cystic fibrosis, autoimmune diseases and inflammatory conditions. By employing a phenotypic assay based on high-content imaging and analysis, we screened a library of biologically active compounds and identified vanilloids as a novel class of chemical compounds able to hinder NETosis induction and NET release. …”
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48517
Table_1_High-Content Screening Identifies Vanilloids as a Novel Class of Inhibitors of NET Formation.DOCX
Published 2019“…Dysregulation of NET production and/or degradation can exert pathogenic effects, contributing to the pathogenesis of various diseases, including cystic fibrosis, autoimmune diseases and inflammatory conditions. By employing a phenotypic assay based on high-content imaging and analysis, we screened a library of biologically active compounds and identified vanilloids as a novel class of chemical compounds able to hinder NETosis induction and NET release. …”
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48518
D−π–A Compounds with Tunable Intramolecular Charge Transfer Achieved by Incorporation of Butenolide Nitriles as Acceptor Moieties
Published 2015“…Chromophores where a polyenic spacer separates a 4<i>H</i>-pyranylidene or benzothiazolylidene donor and three different butenolide nitriles have been synthesized and characterized. …”
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48519
Isoalantolactone enhances radiation-induced G2/M cell cycle arrest in UMSCC-10A cells.
Published 2016“…Those led to an increase in the proportion of cells in G2/M phase; this also led to a slight increase in the number of cells in S phase and a decrease in the number of cells in G1 phase compared with the control. …”
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48520
Up/down regulation of reactions/paths of one compartment when a reaction from another compartment is deleted.
Published 2015“…Although deletion of the reactions shown here causes high up/down regulation in flux in the same compartment or in cytosol but here we focused to observe maximum flux FC in different compartment i.e., change in mitochondria when chloroplastic reaction is deleted and vice versa. Here, CoA, Pyr, IsoCit, <i>α</i>-KG, AcCoA, Cit, Cyt_red, Cyt_ox, Q, QH2, MalOxAc, _ext and _int indicate Coenzyme A, Pyruvate, isocitrate, alpha ketoglutarate, Acetyl-CoA, citrate, cytochrome c reductase, cytochrome c oxidase, ubiquinone, ubiquinol, malate oxaloacetate, external and internal, respectively.…”