A 37 year old female with <i>c-MET</i> amplified CCA, who had progressed on conventional chemotherapy. by Chaitanya R. Churi (678656)

“…After 4 weeks of therapy, (C) axial fused PET-CT and (D) unenhanced CT images show decreased FDG avidity and size of metastases. A representative segment II mass (arrows) has decreased from 2.6 cm to 2.1 cm.…”

Survival curves for HCC patients with the <i>DICER</i> rs3742330 AA genotype (reference) and the GG genotype. by Mi Na Kim (3111618)

“…<p>Patients carrying the rs3742330 GG genotype had a decreased risk (HR, 0.314; 95% CI, 0.135–0.730; <i>P</i> = 0.007) of death compared with those with the AA genotype.…”

Survival curves for HCC patients with the <i>RAN</i> rs14035 CC genotype (reference) and the CT genotype. by Mi Na Kim (3111618)

“…<p>Patients carrying the <i>RAN</i> rs14035 CT genotype showed a decreased risk of death compared with those with the CC genotype (HR, 0.587; 95% CI, 0.349–0.987; <i>P</i> = 0.044).…”

A 69 year old female with KRAS mutated CCA metastatic to the ovaries. by Chaitanya R. Churi (678656)

“…<p>(A) Coronal contrast-enhanced CT image demonstrates a 15.4×12.6×12.2 cm (transverse × craniocaudal × AP) pelvic mass. …”

MRP3 silencing led to reduce excretion rates and increase intracellular demethoxycurcumin-<i>O</i>-glucuronides in HeLa1A1 cells. by Beibei Zhang (509356)

“…<p>(A) MRP3 transporter silencing inhibited the accumlated demethoxycurcumin-<i>O</i>-glucuronides (G1) in extracellular medium; (B) MRP3 transporter silencing decreased the excreted demethoxycurcumin-<i>O</i>-glucuronides (G2) in extracellular solution; (C) MRP3 silencing significantly reduced the excretion rates of G1 and G2; (D) MRP3 silencing resulted in evaluation of intracellular G1 and G2 levels; (E) MRP3 silencing decreased total cellular glucuronidation (G1 ang G2) of demethoxycurcumin; (F) Effects of gene silencing on the protein level of MRP3. …”

Image_1_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.TIF by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

Image_1_Impact of inactivated vaccines on decrease of viral RNA levels in individuals with the SARS-CoV-2 Omicron (BA.2) variant: A retrospective cohort study in Shanghai, China.tif by Peng Yang (296696)

“…We performed the survival data analysis and Generalized Estimating Equation to calculate the adjusted relative risk (aRR) to assess the effect of inactivated vaccines on the decrease of viral RNA levels.…”

Four-fold decrease in [H⁺]_e shifted GLT-1a E_rev by −18 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…<p><b>(A)</b> Representative experiment shows the current as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136111#pone.0136111.g001" target="_blank">Fig 1B</a>. …”

Image_5_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.TIFF by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

Pathways illustrating the network of genomic loci involved with (A & B) Regions undergoing increase in 5mC content and (C & D) decrease in 5mC contents, upon simulated microgravity. by Basudev Chowdhury (2182760)

“…<p>Pathways illustrating the network of genomic loci involved with (A & B) Regions undergoing increase in 5mC content and (C & D) decrease in 5mC contents, upon simulated microgravity.…”

Depletion of CD8 lymphocytes in CD8 Ab-treated macaques resulted in a significant decrease in BCG vaccine-induced immunity against tuberculosis after <i>M. tuberculosis</i> infection. by Crystal Y. Chen (122165)

Image_7_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.TIF by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

Table_1_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.DOCX by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

Image_5_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.TIFF by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

(A-E) Selected signaling pathway schematics demonstrating increase (red bar) or decrease (blue) bar and relative amplitude (height of bar) of differentially expression in each gene and their roles in the signaling pathway depicted. by Vinay Kumar Aakalu (3636064)

Image_1_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.TIF by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

Image_3_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.TIF by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

Eight hours of 10% CSE leads to a decrease in wild-type AQP5 but no change in N228K AQP5 (n = 3; * p<0.05 with ANOVA one-way). by Nadia N. Hansel (359186)

“…<p>Eight hours of 10% CSE leads to a decrease in wild-type AQP5 but no change in N228K AQP5 (n = 3; * p<0.05 with ANOVA one-way).…”

Image_2_The Response of Cupriavidus metallidurans CH34 to Cadmium Involves Inhibition of the Initiation of Biofilm Formation, Decrease in Intracellular c-di-GMP Levels, and a Novel Metal Regulated Phosphodiesterase.TIF by Pablo Alviz-Gazitua (6930746)

“…These results indicate that the response to cadmium in C. metallidurans CH34 inhibits the initiation of biofilm lifestyle and involves a decrease in c-di-GMP levels and a novel metal regulated PDE.…”

The control of <i>phoP</i> by regulatory sRNAs is accompanied by a strong decrease in the steady-state level of <i>phoPQ</i> mRNA, but not always of PhoP protein. by Audrey Coornaert (105790)