G2019S LRRK2 modulates Tf recycling in iPSC-derived human microglia. by Adamantios Mamais (302600)

“…G2019S LRRK2 iPSC microglia exhibited larger Tf vesicles compared to WT while LPS treatment induced a decrease in average vesicle size in both cohorts (C) (minimum 3,000 vesicles were counted from 16 cells per group from 2 differentiations, two-way ANOVA, genotype: <i>P</i> < 0.0001, F(1,17753) = 16.38, treatment: <i>P</i> < 0.0001, F(1,17753) = 20.57). …”

A randomized controlled trial of Roux-en-Y gastrojejunostomy vs. gastroduodenostomy with respect to the improvement of type 2 diabetes mellitus after distal gastrectomy in gastric... by Yoon Young Choi (113840)

“…Sixty percent of RY patients and 20% of BI patients decreased their medication satisfying FBS<126 mg/dL and HbA1c<6.5% and 5% of BI patients stopped their medication satisfying the criteria of FBS<126 mg/dL and HbA1c<6.0%. …”

Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population by Bo Xing (105113)

“…Furthermore, T-1031C <i>C</i> allele (<i>P</i> < 0.001) and G-238A <i>A</i> allele (<i>P</i> < 0.001) were significantly associated with decreased risk of death. …”

Differences in mean daily dissolved oxygen between impoundment and upstream references before and after dam removal, also termed the impoundment DO effect. by Katherine M. Abbott (14135399)

Pyrolysis bio-oil yields (dry bio-oil, daf feedstock) from banagrass as a function of temperature and residence time (bed position, BP). by Trevor James Morgan (787777)

Time constants of approximating exponents as functions of stimulus level, keeping the relative level of the previous stimulus as a parameter; <i>s</i> (silence)–no previous stimulu... by Vladimir V. Popov (5563067)

Fig 4 - by Micha Keller (11312748)

“…The plots show most prominent changes only due to CVH for amplitudes and MFHA durations. There is a positive staircase (increase in both amplitude and MFHA [frequency] duration) for LF band, whereas there is a negative staircase for IM and HF band (amplitudes increase while MFHA [frequency] decrease). …”

Inhibition of DNA-PKcs reduces chemoresistance in RET 9 and RET 51 cells. by Lyle J. Burdine (753645)

Shift toward greater pathologic post-myocardial infarction remodeling with loss of the adaptive hypertrophic signaling of alpha1 adrenergic receptors in mice by Che-Chung Yeh (4615582)

“…</p><p>Results</p><p>Alpha1A-AR knockout paradoxically increased post-MI hypertrophy compared to wild type controls (WT), but also increased ventricular dilatation, fibrosis, apoptosis, and 4-week post-MI mortality (64% in AKO vs. 25% in WT, P = 0.02), suggesting a shift toward greater pathologic hypertrophy in the absence of pro-adaptive alpha1A effects. alpha1A-AR knockout increased phospho-p38 levels in the pre-MI myocardium compared to WT (0.55 ± 0.16 vs. 0.03 ± 0.01, P<0.05) but decreased phospho-ERK1/2 post-MI (0.49 ± 0.35 arbitrary units vs. 1.55 ± 0.43 in WT, P<0.05). …”

Model fit for Mixed-Effects Multi-linear Regressions with PSS-Moderate (PSS> = 14) as a binary outcome measure. by Laura S. P. Bloomfield (3820531)

Acquisition of the mesial and distal direction image. by Cai Wen (13988910)

Sinupret is a robust activator of CFTR-mediated and calcium-activated Cl^- secretion. by Shaoyan Zhang (363713)

“…Sinupret significantly increased ΔI_SC (in µA/cm²)when compared to controls in both WT (20.7+/−0.9 vs. 5.6+/−0.9, p<0.05) and CFTR^−/− MNSE (ΔI_SC in µA/cm², 10.1+/−1.0 vs. 0.9+/−0.3, p<0.05). …”

<i>Arabidopsis</i> PEX19 is farnesylated. by Margaret M. McDonnell (2175666)

“…<p>(A) Proteins with a C-terminal CaaX motif (Cys-aliphatic-aliphatic-X; where X can be Ser, Met, Ala, Asn, or Cys) can be farnesylated by a protein farnesyl-transferase complex composed of PLP and ERA1, cleaved of the three carboxyl-terminal residues, and methylated (me) on the carboxyl group of the prenylated Cys residue [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148335#pone.0148335.ref059" target="_blank">59</a>]. …”

Fig 3 - by Micha Keller (11312748)

“…<p>Estimated marginal means (± SE) of momentary frequency of highest amplitude (MFHA; A.1-A.3) as well as amplitudes (B.1-B.3) for each intervention, LF, IM, and HF frequency bands, and each section. …”

Effect of BCA mix on body weight (A), adiposity index (B), food intake (C) and water intake (D). by Mohamed Siliman Misha (19232949)

Fig 2 - by I. Moll (14227650)

The evolution of the differences between the combined and whole global binding-folding energy landscapes as a function of . by Xiakun Chu (151393)

Centromeric fork stalling/termination is CENP-A mediated and involves Rad51 and Rad52. by Sreyoshi Mitra (555232)

“…The RIT values, plotted on a bar graph, indicate a gradual decrease in the termination signal in CENP-A^CaCse4 repressed conditions as compared to wild-type. …”

Patient demographics. by Yongwoo Lee (2265172)

“…Redness in the nasal limbal and bulbar conjunctivae significantly decreased. The mean LLT tended to increase after treatment. …”

Acquisition of the sagittal direction image. by Cai Wen (13988910)