Development of guinea pig monaural auditory brainstem responses (ABRs). by Kelsey L. Anbuhl (22190594)

“…<p>(a) <i><i>Inset</i></i>: The ABR is an auditory-evoked potential that displays peaks (black trace, waves I–IV) corresponding to locations along the ascending auditory pathway. …”

The effect of sGP on immune response when antigen exposure mimics natural infection. by Gopi S. Mohan (111744)

“…<p>(A) Immunization study design. Female BALB/C mice were immunized IM with 50 µg of total DNA per immunization according to the schedule shown. …”

E2F6 Impairs Glycolysis and Activates BDH1 Expression Prior to Dilated Cardiomyopathy by Jennifer L. Major (3639472)

“…Using the Seahorse platform, a 22% decrease in glycolysis was noted in neonatal cardiomyocytes isolated from E2F6-Tg hearts. …”

Image1_Exploring cell-derived extracellular vesicles in peripheral blood and bone marrow of B-cell acute lymphoblastic leukemia pediatric patients: proof-of-concept study.tiff by Fábio Magalhães-Gama (11483503)

“…Our results demonstrate that B-ALL patients had a marked production of EV-CD51/61⁺, EV-CD10⁺, EV-CD19⁺ and EV-CD10⁺CD19⁺ (double-positive) with a decrease in EV-CD41a⁺ on D0. …”

Data_Sheet_1_Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibrosis.docx by Joana Alpoim-Moreira (13239594)

“…The hypermethylation of MMP2 and MMP9, but not of COL1A1 genes, occurred simultaneously with a decrease in their mRNA levels, with endometrial fibrosis, suggesting that this hypermethylation is responsible for repressing their transcription. …”

Data_Sheet_1_Effects of Aleurone Supplementation on Glucose-Insulin Metabolism and Gut Microbiome in Untrained Healthy Horses.docx by Berit Boshuizen (3747655)

“…There was a significant dose-dependent increase in the postprandial time to peak of glucose (p = 0.030), a significant delay in the time to peak of insulin (p = 0.025), and a significant decrease in both the insulin peak level (p = 0.049) and insulin area under the curve (AUC) (p = 0.019) with increasing dose levels of aleurone, with a consideration of 200 g being the lowest significant dose. …”

Image_1_TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals.TIFF by José M. Jiménez (3043077)

“…The participation of TLR4 was confirmed through a decrease in IL-12p40 and IL-6 secretion induced by FLH when a TLR4 blocking antibody was used; a reduction was also observed in DCs from C3H/HeJ mice, a mouse strain with a nonfunctional mutation for this receptor. …”

Image3_Exploring cell-derived extracellular vesicles in peripheral blood and bone marrow of B-cell acute lymphoblastic leukemia pediatric patients: proof-of-concept study.tiff by Fábio Magalhães-Gama (11483503)

“…Our results demonstrate that B-ALL patients had a marked production of EV-CD51/61⁺, EV-CD10⁺, EV-CD19⁺ and EV-CD10⁺CD19⁺ (double-positive) with a decrease in EV-CD41a⁺ on D0. …”

Imidazole Substituent Effects on Oxidative Reactivity of Tripodal(imid)₂(thioether)Cu^I Complexes by Lei Zhou (19808)

“…In the search for new bis(imidazole)thioether (BIT) copper complexes that accurately mimic the electronic and reactivity features of the Cu_M site of copper hydroxylase enzymes, a set of tripodal BIT ligands <b>4a</b>,<b>b</b>−<b>6a</b>,<b>b</b> has been synthesized that vary according to the imidazole <i>C-</i>(Ph or H) and <i>N</i>-(H or Me) substituents, as well as the position (2- or 4-) of the tripodal attachment. …”

Thymocytes in γδ T cell-deficient mice. by Swati Popat Phalke (6876818)

“…The representative flow cytograms show an increase in the relative frequency of CD8-single-positive CD122+CD44+ TCR-β+ thymocytes in B6.TCR-Vγ4/6KO mice, and a relative decrease of CD4-single-positive CD122+CD44+ TCR-β+ thymocytes. …”

Data_Sheet_1_Reconfiguration of Functional Dynamics in Cortico-Thalamo-Cerebellar Circuit in Schizophrenia Following High-Frequency Repeated Transcranial Magnetic Stimulation.docx by Huan Huang (724980)

“…In addition, higher alteration in FC temporal variability between left DLPFC and right posterior parietal thalamus predicted a higher remission ratio of negative symptom scores, indicating that the decrease of FC temporal variability between the brain regions was associated with the remission of schizophrenia severity. …”

Imidazole Substituent Effects on Oxidative Reactivity of Tripodal(imid)₂(thioether)Cu^I Complexes by Lei Zhou (19808)

“…In the search for new bis(imidazole)thioether (BIT) copper complexes that accurately mimic the electronic and reactivity features of the Cu_M site of copper hydroxylase enzymes, a set of tripodal BIT ligands <b>4a</b>,<b>b</b>−<b>6a</b>,<b>b</b> has been synthesized that vary according to the imidazole <i>C-</i>(Ph or H) and <i>N</i>-(H or Me) substituents, as well as the position (2- or 4-) of the tripodal attachment. …”

Data Sheet 1_Crosstalk between MSC-extracellular vesicles and Olea europaea leaf extract in encapsulated liposomal hydrogel: attenuation of neuroinflammation and brain neurotransmi... by Doaa Ibrahim (12910718)

“…The findings of this study demonstrated that the neuroprotective effect of the combined Lipo-OLE-Hydrogel and MSC-Exo treatment was associated with a significant reduction in oxidative stress, as evidenced by the restoration of total antioxidant capacity and the marked decrease in oxidative biomarkers, including reactive oxygen species (ROS), H₂O₂, and malondialdehyde (MDA). …”

Simulating the seismic signal of phase transtions in the deepest mantle by Andrew Walker (411843)

“…</p> <p><br>These calculations show clear differences in global and local scale elastic anisotropy in the lowermost mantle between cases where texture is allowed to persist through the phase transitions and those where it is not. On a global scale and when radial anisotropy is imposed<br>the inclusion of topotaxy results in a dramatic decrease in the strength of the degree two signal and better agreement between observations and the model for post­perovskite deformation where dislocations moving on (001) dominate. …”

Image2_Exploring cell-derived extracellular vesicles in peripheral blood and bone marrow of B-cell acute lymphoblastic leukemia pediatric patients: proof-of-concept study.tiff by Fábio Magalhães-Gama (11483503)

“…Our results demonstrate that B-ALL patients had a marked production of EV-CD51/61⁺, EV-CD10⁺, EV-CD19⁺ and EV-CD10⁺CD19⁺ (double-positive) with a decrease in EV-CD41a⁺ on D0. …”

Imidazole Substituent Effects on Oxidative Reactivity of Tripodal(imid)₂(thioether)Cu^I Complexes by Lei Zhou (19808)

“…In the search for new bis(imidazole)thioether (BIT) copper complexes that accurately mimic the electronic and reactivity features of the Cu_M site of copper hydroxylase enzymes, a set of tripodal BIT ligands <b>4a</b>,<b>b</b>−<b>6a</b>,<b>b</b> has been synthesized that vary according to the imidazole <i>C-</i>(Ph or H) and <i>N</i>-(H or Me) substituents, as well as the position (2- or 4-) of the tripodal attachment. …”

<i>C</i>. <i>elegans</i> SNX-3 is required for formation of clathrin-independent recycling endosomal tubules. by Yangli Tian (4871416)

“…<p>(A) Confocal images provide the effect of various SNX mutant or RNAi treatment on the subplasmalemmal hTAC-GFP-containing tubular endosomes. …”

Table_3_Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation.XLSX by Alessia Buso (6653861)

“…Based on quantitative immunoblot analyses, in both groups a reduction of two key regulators of mitochondrial biogenesis/remodeling and activity, namely PGC-1α and Sirt3, was revealed during bed-rest, with a subsequent up-regulation after rehabilitation, indicating an involvement of PGC-1α-Sirt3 axis in response to the treatments. …”

DataSheet_1_Comparison of the effects of monounsaturated fatty acids and polyunsaturated fatty acids on the lipotoxicity of islets.pdf by Wen Liu (39804)

“…However, when fed diets containing a high proportion of UFAs (20% of energy), both the FO and OO groups exhibited substantially improved glucose and lipid metabolism, such as decrease in total cholesterol (TC), low-density lipoprotein (LDL), fasting blood glucose (FBG), and fasting blood insulin (FBI)) and improvement of insulin sensitivity evidenced by intraperitoneal glucose tolerance test (IPGTT) and intraperitoneal insulin tolerance test (IPITT). …”

Data_Sheet_1_Hypoxia signaling in the equine small intestine: Expression and distribution of hypoxia inducible factors during experimental ischemia.PDF by Nicole Verhaar (8781686)

“…After reperfusion, the cytoplasmic staining of the crypt and villus enterocytes as well as the villus nuclear staining significantly increased, whereas the perinuclear granules in the crypts decreased. The protein levels showed a significant decrease in group C at reperfusion, with lower HIF1α levels in group C compared to group IPoC during ischemia and reperfusion. …”