Metformin treatment reduces the mRNA levels of proinflammatory cytokines in human HT-29 cells. by Seon-Yeong Lee (403007)

“…<p>(A) Tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-8 mRNA expression levels decreased in human HT-29 cells stimulated with LPS and then treated with metformin. …”

Sample characteristics throughout the study duration. by Alexander J. Ehrenberg (10880032)

“…<p>(A) The proportion of samples (n = 11,971) that returned with a specimen insufficient value decreased throughout the study. …”

Insulin-producing cells (IPCs) regulate reproductive dormancy in <i>D</i>. <i>melanogaster</i>. by Luca Schiesari (3186768)

“…<p>(A) Ablation of IPCs with <i>dilp2>hid</i>,<i>rpr</i> and <i>Insp3>hid</i>,<i>rpr</i> significantly enhances diapause at both 11 and 28 days compared with controls even under a long summer photoperiod (LD16:8). …”

Transcriptional deregulation of gene markers involved in pathological processes. by Michal Mielcarek (195209)

“…<p>(A) <i>S100A4</i> (S100 calcium binding protein A4), (B) <i>Vgl-4</i> (vestigial related factor 4) transcripts were up-regulated while (C) <i>Myh6</i> (myosin heavy light chain 6) (D) <i>Myh7</i> (myosin heavy light chain 7) and (E) <i>Bdnf</i> (brain derived neurotophic factor) mRNAs were significantly decreased in the heart of R6/2 and <i>Hdh</i>Q150 mice. …”

Examples of proteins with putative high bi-stability. by Tobias Sikosek (135058)

“…</p>b<p>Root Mean Square Deviation of backbone atoms; in units of Å.…”

Supplemental Fig. S2 from RNF6 Inhibits Lung Adenocarcinoma Cell Proliferation by Promoting Cyclin D2 Degradation by Yuening Sun (21232876)

“…<p>Supplemental Fig. S2. RNF6 decreases the half-life of CCND2. (A) A549 and NCI-H1299 cells were transfected a Flag-RNF6 plasmid for 48 hrs, followed by treatment with MG132 for 8 hrs and IP/IB assays. …”

Effects of 18β-GA on cell proliferation and apoptosis. by Run-Yue Huang (546049)

“…<b>C</b>, Western blot analysis demonstrated the increased cleaved PARP (85 kDa) with the decreased full length PARP (116 kDa) in A549 and NCI-H460 cells treated with 18β-GA. …”

Lysozyme c-1 knockdown (KD) significantly reduced prevalence and intensity of <i>P. berghei</i> infections. by Mayur K. Kajla (186122)

“…<p>The results of three independent replicate experiments for the <i>An. gambiae</i> G3 strain are shown. (A) Shows the significantly decreased prevalence of infection in the <i>LYSC-1</i> KD mosquitoes. …”

Effect of plate washing on the dissociation of ACE inhibitor from ACE. by Sergei M. Danilov (118956)

“…The ZPHL/HHL ratio for ACE in solution in the presence of the inhibitor (red bar in the right column) is shown for comparison. Data are expressed as a % of control (i.e. ACE without inhibitor) and presented as a mean of at least 3 independent experiments. …”

Data Sheet 1_Use of HLA desensitization in the management of renal transplant recipients in Europe.pdf by Lionel P. E. Rostaing (22138330)

“…As the degree of sensitization increases, the likelihood of finding a compatible organ decreases. Desensitization is the process of reducing recipient anti-HLA antibodies to acceptable levels to allow transplantation. …”

Time-dependent effects of increasing RSV concentrations on XBP1 splicing, CHOP expression and viability. by Cristina Rojas (667363)

“…The viability was evaluated using a MTT assay. The data are shown as the mean ± SD of three independent experiments. …”

AV counting and distribution for neurons exposed to different treatments. by Mehrdad Alirezaei (51956)

“…<p>(A) Total AV counting results show that a significant drop occurs in neurons exposed to TNF-α or NMDA for 3 or 24 hr. *** <i>P</i><0.001, ** <i>P</i><0.01 for <i>n</i> = 6 experiments. …”

Daily administration of morphine, midazolam and propofol and percentages of patients needing these sedatives by Denise P Veelo (38856)

“…</p><p></p> Data are expressed as mean DD/MDD. When comparing the summed data of seven days before and after tracheotomy there was a significant difference in dosage and percentage of patients using these sedatives before and after tracheotomy (< 0.01 with the Wilcoxon signed-rank test and the McNemar test). …”

Impact of the Identification Strategy on the Reproducibility of the DDA and DIA Results by Carolina Fernández-Costa (2151589)

“…The reproducibility of quantification was also improved with library search compared to database search, with the mean of the coefficient of variation decreasing more than 30% and a reduction in the number of missing values of more than 35%. …”

Transcriptional deregulation of HD markers involved in heart failure. by Michal Mielcarek (195209)

“…<p>(A) <i>S100A4</i> (S100 calcium binding protein A4), Vgl-3 (vestigial related factor 3), <i>Vgl-4</i> (vestigial related factor 4) were up-regulated while <i>Mck</i> (muscle creatine kinase) and <i>Bdnf</i> (brain derived neurotophic factor) transcripts were significantly decreased in the heart of R6/2 mice. …”

Levels of dioxins and dioxin-like PCBs in food of animal origin in the Netherlands during the period 2001–2011 by Paulien Adamse (774690)

“…In general, only minor decreases in mean PCDD/F and DL-PCB concentrations could be observed for the period 2001–2011. …”

Impact of the Identification Strategy on the Reproducibility of the DDA and DIA Results by Carolina Fernández-Costa (2151589)

“…The reproducibility of quantification was also improved with library search compared to database search, with the mean of the coefficient of variation decreasing more than 30% and a reduction in the number of missing values of more than 35%. …”

Soma diameter in DEX treated animals compared to the relevant control group. by Verena Scheper (538613)

“…DEX elution out of the implant in two concentrations (study II) increased the soma diameter compared to the relevant control group over the full cochlear length (C) but not in the basal region (D). Using a pump-delivery-system (study III) DEX decreased the soma diameter compared to AP- and AP+ES-treated ones in the entire cochlea (E) but not in the basal region (F). …”

FA and glucose oxidations in SCD1-overexpressed cardiac myocytes. by Hiroki Matsui (330019)

“…(D): PA (50 to 100 µM) -induced suppression of glucose oxidation recovered in cardiac myocytes transduced with Ad-SCD1 (▪) in comparison with control cells transduced with Ad-LacZ (□). BSA was used as a vehicle. Each sample was counted in a scintillation counter (cpm) and data are shown as the mean ± SD. …”

Granuloma scores. by Masahiro Ishizuka (795418)

“…The data are presented as the means ± standard errors of the mean (SEs) for each group (day 0–10: n = 7–11, control group: n = 10, PDE group: n = 11, anti-IL-17A group: n = 8). *: <i>P</i> < 0.05, **: <i>P</i> < 0.01, ***: <i>P</i> < 0.001.…”