4-PBA alleviates ER stress in dystonia models. by Jin A. Cho (656426)

“…The results indicate that the presence of torsinAΔE induces ER stress in fibroblast cells, however, 10 mM 4-PBA treatment decreases ER stress in DYT1 patient lines.…”

A Double Negative Loop Comprising <i>ETV6/RUNX1</i> and <i>MIR181A1</i> Contributes to Differentiation Block in t(12;21)-Positive Acute Lymphoblastic Leukemia by Yung-Li Yang (514952)

“…Moreover, ectopic expression of miR-181a also resulted in decreased CD10 hyperexpression in <i>ETV6/RUNX1</i>^<i>+</i> primary patient samples. …”

DataSheet1_Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.docx by Shukun Sun (11510686)

“…Moreover, the alleviating effects of ADK inhibition on ER stress, inflammation, and cell necroptosis were eliminated by the adenosine A_2A receptor antagonist.</p><p>Conclusion: ADK inhibition reduced inflammation and necroptotic acinar cell death in SAP via the adenosine A_2A receptor/ER stress pathway, suggesting that ADK might be a potential therapeutic target for SAP.…”

Smooth Things Come in Threes: A Diabatic Surrogate Model for Conical Intersection Optimization by Ignacio Fdez. Galván (7450859)

“…Using this model with the restricted variance optimization method results in a notable decrease of the overall computational effort required to obtain minimum energy crossing points.…”

Induction of Peroxisomes by Butyrate-Producing Probiotics by Huachun Weng (690096)

“…Tributyrin or 4-PBA treatment significantly decreased body weight and increased hepatic mRNA expression of peroxisome proliferator-activated receptor-α (<i>PPARα</i>) and <i>Pex11a</i>. …”

Signal intensity plots from knockdown data for StAR (A) and CYP19A (B). by Roseanne Rosario (130971)

“…CYP19A, usually activated by FOXL2 shows a significant decrease (p = 0.03) in expression following the knockdown of mutant FOXL2. …”

<i>SpdA-ins</i> cells adhere more efficiently than WT cells to their substrate. by Marco Dias (290981)

“…A decrease in cell detachment can be the result of an increase in the adhesion force (F) or of a decrease in h (i.e. of a more efficient cell spreading).…”

Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues. by Kumaraswamy Naidu Chitrala (612025)

“…<p>Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues.…”

Both JMJD1A and BACH1 were the direct targets of miR-155. by Zi-Ming Du (223324)

“…Pairing of miR-155 with JMJD1A 3′UTR region. (C). Overexpression of miR-155 by the miR-155 mimic resulted in a significant decrease in luciferase signals of pMIR-report-JMJD1A 3′UTR (JMJD1A) and pMIR-report-BACH1 3′UTR (BACH1) transfected HEK 293 cells, but not in pMIR-report-vector (vector) transfected HEK 293 cells.…”

Characteristic Features of CO₂ and CO Adsorptions to Paddle-Wheel-type Porous Coordination Polymer by Jia-Jia Zheng (1480219)

“…For all cases, the exchange repulsion with the organic linker decreases to a larger extent than the attractive electrostatic and dispersion interactions decrease when going from the normal position to the deviating one. …”

Effects of HP1a depletion on focal movement. by Raghuvar Dronamraju (204100)

“…The western blot shows a decrease in the level of HP1a, but not HP1b or -c. …”

Whole brain activation as a function of illness course. by Maggie M. Sweitzer (3167943)

Splicing to include exon 3a is a developmentally regulated event in skeletal muscle. by Meghan C. Drummond (466384)

“…(<b>B</b>) qPCR of RNA harvested in Trizol showed that concurrent with a decrease in normal <i>Actg1</i>, splicing to generate alternative <i>Actg1</i> increases during differentiation into myotubes. …”

Example of a network. by Aurélie Pistono (3912550)

“…Blurriness did not lead to more disfluency on average and viewing times decreased with blurred pictures. However, multivariate pattern analyses revealed that a classifier could predict above chance, from the pattern of disfluency, whether each participant was about to name blurred or control pictures. …”

The effect of G1613A mutations on the levels of HBsAg and HBeAg. by Man-Shan Li (347605)

“…<p>(<b>A</b>) Intracellular level of HBsAg, (<b>B</b>) extracellular level of HBsAg, (<b>C</b>) intracellular level of HBeAg and (<b>D</b>) extracellular level of HBeAg were measured after transfection with 1.3× HBV genomes with indicated mutations into HuH7 cells by ELISA as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021856#s2" target="_blank">materials and methods</a>. …”

Decreased Memory B Cells and Increased CD8 Memory T Cells in Blood of Breastfed Children: The Generation R Study by Michelle A. E. Jansen (740955)

“…</p><p>Results</p><p>Per month continuation of breastfeeding, a 3% (95% CI -6, -1) decrease in CD27+IgM+, a 2% (95 CI % -5, -1) decrease in CD27+IgA+ and a 2% (95% CI -4, -1) decrease in CD27-IgG+ memory B cell numbers were observed at 6 months of age. …”

TUDCA decreases MPO with improved mitochondrial biogenesis, mitochondria-ER contact, and alveolar formation of HOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…<p>(<b>A</b>) The increased MPO levels in HOX neonatal lungs are decreased by TUDCA treatment (0.1±0.1-fold; n = 6, p<0.05). …”

Filipin-treated A549 cells have significantly fewer viable intracellular bacteria after uptake. by Kari Fine-Coulson (135880)

“…The calculated fold change from T0 to T24 indicates a significant decrease in the number of viable intracellular bacteria over time (B) (*p-value <0.001). …”

A. Gene expression of <i>SFRP1</i> during ACS measured by mRNA expression microarray analysis.... by Árpád V. Patai (132272)

“…<p>SFRP1 protein expression gradually decreased during ACS. The epithelial SFRP1 expression showed a continuous decrease during ACS. …”

Neural networks classify states which differ in neuronal activity levels using ensembles of neurons that increase/decrease their activity in each state. by Nicholas A. Frost (10739821)

“…As a result, there is an increase (neurons 51:100) or decrease (neurons 1:50) in activity levels in State B compared to State A. …”