Table_2_Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population.docx by Xiao Tan (217064)

“…Functional experiments revealed a downregulation of IL1RL1, IL18R1, and SLC9A4 and a decreased secretion of IFN-γ in the anti-CD3/CD28 antibody-treated PBMCs as well as a decreased production of TNF-α in the lipopolysaccharide (LPS)-stimulated PBMCs in carriers of the protective homozygous rs12987977/GG genotype compared with the TT genotype. …”

Risk Factors Associated with Colorectal Cancer in a Subset of Patients with Mutations in <i>MLH1</i> and <i>MSH2</i> in Taiwan Fulfilling the Amsterdam II Criteria for Lynch Syndro... by Abram Bunya Kamiza (751340)

“…</p><p>Results</p><p>Among the total cohort, subjects of the Hakka ethnicity exhibited an increased CRC risk (HR = 1.62, 95% CI = 1.09–2.34); however, those who performed regular physical activity exhibited a decreased CRC risk (HR = 0.62, 95% CI = 0.41–0.88). …”

Image_3_Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population.jpg by Xiao Tan (217064)

“…Functional experiments revealed a downregulation of IL1RL1, IL18R1, and SLC9A4 and a decreased secretion of IFN-γ in the anti-CD3/CD28 antibody-treated PBMCs as well as a decreased production of TNF-α in the lipopolysaccharide (LPS)-stimulated PBMCs in carriers of the protective homozygous rs12987977/GG genotype compared with the TT genotype. …”

Image_1_Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population.jpg by Xiao Tan (217064)

“…Functional experiments revealed a downregulation of IL1RL1, IL18R1, and SLC9A4 and a decreased secretion of IFN-γ in the anti-CD3/CD28 antibody-treated PBMCs as well as a decreased production of TNF-α in the lipopolysaccharide (LPS)-stimulated PBMCs in carriers of the protective homozygous rs12987977/GG genotype compared with the TT genotype. …”

Image_5_Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population.jpg by Xiao Tan (217064)

“…Functional experiments revealed a downregulation of IL1RL1, IL18R1, and SLC9A4 and a decreased secretion of IFN-γ in the anti-CD3/CD28 antibody-treated PBMCs as well as a decreased production of TNF-α in the lipopolysaccharide (LPS)-stimulated PBMCs in carriers of the protective homozygous rs12987977/GG genotype compared with the TT genotype. …”

Table_1_Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population.docx by Xiao Tan (217064)

“…Functional experiments revealed a downregulation of IL1RL1, IL18R1, and SLC9A4 and a decreased secretion of IFN-γ in the anti-CD3/CD28 antibody-treated PBMCs as well as a decreased production of TNF-α in the lipopolysaccharide (LPS)-stimulated PBMCs in carriers of the protective homozygous rs12987977/GG genotype compared with the TT genotype. …”

Image_2_Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population.jpg by Xiao Tan (217064)

“…Functional experiments revealed a downregulation of IL1RL1, IL18R1, and SLC9A4 and a decreased secretion of IFN-γ in the anti-CD3/CD28 antibody-treated PBMCs as well as a decreased production of TNF-α in the lipopolysaccharide (LPS)-stimulated PBMCs in carriers of the protective homozygous rs12987977/GG genotype compared with the TT genotype. …”

Image_4_Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population.jpg by Xiao Tan (217064)

“…Functional experiments revealed a downregulation of IL1RL1, IL18R1, and SLC9A4 and a decreased secretion of IFN-γ in the anti-CD3/CD28 antibody-treated PBMCs as well as a decreased production of TNF-α in the lipopolysaccharide (LPS)-stimulated PBMCs in carriers of the protective homozygous rs12987977/GG genotype compared with the TT genotype. …”

Clustering of gene expression of the MFH samples with the RCC gene set (A), OVCA gene set (B), AF gene set (C), and the protein kinase gene set (D) as described in the text by Keith M Skubitz (92866)

“…MFH-1 to MFH-9 grouped together in panel A and are indicated by an asterisk. The tissue samples in the tree are joined by very short branches if they have gene expression patterns that are very similar to each other, and by increasingly longer branches as their similarity decreases.…”

Changes in the concentration of lactate, bicarbonate (HCO), base excess (BE) and chloride (Cl) after a patient with septic shock was placed on high-volume hemofiltration (HVHF) and... by Rinaldo Bellomo (982)

“…</p><p>Copyright © 2002 BioMed Central Ltd</p> The acidifying effect of hyperlactatemia (fall in bicarbonate and in base excess) was markedly attenuated by a decrease in serum chloride concentration (chloride shift). …”

Protein Tyrosine Phosphatase Oligomerization Studied by a Combination of ¹⁵N NMR Relaxation and ¹²⁹Xe NMR. Effect of Buffer Containing Arginine and Glutamic A... by Jascha Blobel (2383873)

“…These experimental conditions are shown to enhance specific protein−protein interactions while decreasing nonspecific aggregation. In addition, ¹²⁹Xe NMR chemical shifts become selective reporters of one particular oligomer in the presence of arginine and glutamic acid, indicating that a specific Xe binding site is created in the oligomerization process. …”

Protein Tyrosine Phosphatase Oligomerization Studied by a Combination of ¹⁵N NMR Relaxation and ¹²⁹Xe NMR. Effect of Buffer Containing Arginine and Glutamic A... by Jascha Blobel (2383873)

“…These experimental conditions are shown to enhance specific protein−protein interactions while decreasing nonspecific aggregation. In addition, ¹²⁹Xe NMR chemical shifts become selective reporters of one particular oligomer in the presence of arginine and glutamic acid, indicating that a specific Xe binding site is created in the oligomerization process. …”

Survival of winter wheat plants acclimated to the cold at 4°C while growing under a 12 h light/12 h dark photoperiod for 5 weeks and then exposed to subzero temperatures. by Daniel Z. Skinner (769718)

Supplementary file 1_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…</p>Conclusion<p>This study found no association between ACE2 rs2106809 genetic variant and susceptibility to SARS-CoV-2 infection, whilst the rs2285666 T-allele was associated with a decreased frequency for SARS-CoV-2 infection among Ghanaian females. …”

Baseline progression risk for the model in the top part of <b>Table 4</b>, for a non-black participant in the San Francisco Veterans Affairs Medical Center liver studies cohort [17... by Peter Bacchetti (75155)

“…All transitions have decreasing hazard, reflecting the odds ratios <1 in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020104#pone-0020104-t004" target="_blank">Table 4</a> for years in stage. …”

Increased <i>BACE1</i> RNA and reduced <i>ADAM10</i> RNA expression levels in brain tissue from guinea pigs fed a high cholesterol diet. by Mathew J. Sharman (425316)

“…<p>Quantitative PCR analysis analysis for (A) ADAM10 and (B) BACE1 expression on total RNA extracted from the frontal cortex and cerebellum of guinea pigs fed the control or cholesterol diets. …”

Gene Expression Profiles of Fenofibrate Effects in mouse grafts and spleens: significant repression of IL17 and Th1 genes in vivo in spleens and grafts and formation of a single ne... by Silke Roedder (379898)

“…<p>PCR of RNA from mice cardiac allografts (5a) and recipient spleens (b) corroborated in vitro findings and further characterized the mechanism of Fenofibrate to regulate the IL17 pathway and Th1 response (c). …”

GFAP-positive cells in the DCN of the NC, 21D-B, and 21D-B/T (A) or 7D-B, and 7D-B/T (B) groups were quantified and statistically analyzed. by Xiaoping Du (284656)

“…Significantly increased GFAP expression is observed in the <i>lateral</i> and <i>middle</i> regions of the 21D-B and 7D-B groups compared to the NC group (all <i>p</i> < 0.05). Decreased numbers of GFAP-positive cells were observed in these two regions in the 21D-B/T group compared to the 21D-B group (A, all <i>p</i> < 0.05), suggesting a treatment effect in these regions at this time point after blast exposure. …”

Immunostaining of nucleostemin (NS) (A–C), semi-quantitation (D) and qRT-PCR analysis of gene expression (E, F) in aging TSCs subjected to mechanical loading <i>in vitro</i>. by Jianying Zhang (256508)

“…<p>Patellar TSCs isolated from aging mice (9 months old) were subjected to no stretching (Control), 4% stretching or 8% stretching followed by the analyses. Immunostaining (<b>A–C</b>) and semi-quantitation (<b>D</b>) showed that compared to the control without stretching, 4% stretching increased the number of NS-expressing TSCs, whereas 8% stretching further decreased it. qRT-PCR analysis of the expression of three stem cell and tenocyte-related genes, Nanog, collagen I and tenomodulin (<b>E</b>) and three non-tenocyte related genes, LPL, Sox-9 and Runx-2 (<b>F</b>) showed that 4% stretching effectively up-regulated Nanog, collagen I and tenomodulin, but 8% was less effective (<b>E</b>). …”

Scale-Adjusted Metrics for Predicting the Evolution of Urban Indicators and Quantifying the Performance of Cities by Luiz G. A. Alves (441209)

“…Simple linear models account for 31%–97% of the observed variance in data and correctly reproduce the average of the scale-adjusted metric when grouping the cities in above and below the allometric laws. We further employ these models to forecast future values of urban indicators and, by visualizing the predicted changes, we verify the emergence of spatial clusters characterized by regions of the Brazilian territory where we expect an increase or a decrease in the values of urban indicators.…”