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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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145441
Presentation_1_Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain.PPTX
Published 2022“…An eQTL was revealed to significantly affect EGLN2 expression in the European sample and two mQTLs were respectively detected in CpG sites in NRXN1 and CYP2A7. Interestingly, we found for the first time that the minor allele of the single nucleotide polymorphism (SNP) rs3745277 located in CYP2A7P1 (downstream of CYP2B6) significantly decreased methylation at the CpG site for CYP2A7 (cg25427638; P = 5.31 × 10<sup>–7</sup>), reduced expression of CYP2B6 (P = 0.03), and lowered the percentage of smokers (8.8% vs. 42.3%; Odds Ratio (OR) = 0.14, 95% Confidence Interval (CI): 0.02–0.62; P = 4.47 × 10<sup>–3</sup>) in a dominant way for the same cohort sample. …”
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145442
Video_2_Hearing Someone Laugh and Seeing Someone Yawn: Modality-Specific Contagion of Laughter and Yawning in the Absence of Others.WMV
Published 2022“…We investigated how these two sensory modalities contribute to the contagion of laughter and yawning under controlled laboratory conditions in the absence of a social situation that might confound their contagion. …”
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145443
Covariance of shape fluctuations and eigenworms.
Published 2013“…Worm images are recorded at times synchronized to a heat pulse and we display <i>σ</i><sup>2</sup><i><sub>K</sub></i> aligned with this pulse (red line). …”
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145444
NOTCH1 Gain of Function in Germ Cells Causes Failure of Spermatogenesis in Male Mice
Published 2013“…Using a <i>Stra8-icre</i> transgene we produced mice with conditional activation of the NOTCH1 intracellular domain (NICD) in germ cells. …”
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145445
Table_1_Microplastic Intake, Its Biotic Drivers, and Hydrophobic Organic Contaminant Levels in the Baltic Herring.docx
Published 2019“…To predict MP abundance in fish guts, we constructed a mass-balance model using literature data on MP in the water column and physiological rates on ingestion and gut evacuation for clupeids of a similar size. …”
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145446
Data_Sheet_1_Arabidopsis FHY3 and FAR1 Function in Age Gating of Leaf Senescence.pdf
Published 2021“…In addition, we show that FHY3, PIF5, and EIN3 form a tri-protein complex(es) and that they coordinately regulate the progression of leaf senescence. …”
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145447
Expression Profiling of Rectal Tumors Defines Response to Neoadjuvant Treatment Related Genes
Published 2014“…Nevertheless, identification of patients who have a higher likelihood of responding to preoperative CRT could be crucial in decreasing treatment morbidity and avoiding expensive and time-consuming treatments. …”
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145448
Video_1_Hearing Someone Laugh and Seeing Someone Yawn: Modality-Specific Contagion of Laughter and Yawning in the Absence of Others.WMV
Published 2022“…We investigated how these two sensory modalities contribute to the contagion of laughter and yawning under controlled laboratory conditions in the absence of a social situation that might confound their contagion. …”
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145449
<i>In Vivo</i> Activation of Duocarmycin–Antibody Conjugates by Near-Infrared Light
Published 2017“…A modest change to the ethylenediamine linker (<i>N</i>,<i>N</i>′-dimethyl to <i>N</i>,<i>N</i>′-diethyl) leads to a bathochromic shift in the absorbance maxima, while decreasing background hydrolysis. …”
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145450
Pan-coronavirus fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and simian immunodeficiency virus
Published 2021“…In the outbreak of COVID-19, we generated a lipopeptide EK1V1 by modifying EK1 with cholesterol, which exhibited significantly improved antiviral activity. …”
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145451
Table_1_Understory Community Assembly Following Wildfire in Boreal Forests: Shift From Stochasticity to Competitive Exclusion and Environmental Filtering.docx
Published 2018“…We found that random patterns of phylogenetic, functional, and trait dispersions were dominant for most of our surveyed plots, indicating that stochastic processes may play a crucial role in the determination of understory community assembly. …”
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145452
Environment-Friendly Antibiofouling Superhydrophobic Coatings
Published 2019“…We demonstrate our coating on a variety of metallic and nonmetallic surfaces with dip-coating of aluminum, absorbent fabrics, glass, and even paper. …”
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145453
Poster ATVB2022 MDG.pptx
Published 2023“…At the cellular level, Dhdds LSKO mice showed hepatic endoplasmic reticulum (ER) stress and decreased N-linked glycosylation. In addition, we observed significant downregulation of Sterol Regulatory Element-Binding Protein 1c (Srebp-1c) - a key regulator of de novo lipogenesis (DNL) - and downstream-regulated genes in the DNL pathway. …”
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145454
Data_Sheet_1_Growth Temperature Influence on Lipids and Photosynthesis in Lepidium sativum.PDF
Published 2020“…This revealed that plants developing at temperatures above the optimum have a lower photosynthetic efficiency. Moreover, plants grown under elevated and low temperatures showed a different galactolipid profile, especially the amount of saturated galactolipids decreased at low temperature and increased at high temperature. …”
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145455
DataSheet_1_Characterizing and Evaluating Diurnal Salivary Uric Acid Across Pregnancy Among Healthy Women.pdf
Published 2022“…Using multilevel linear models, we found sUA increased across pregnancy and displayed a robust diurnal pattern with the highest concentrations at waking, a steep decline in the early morning, and decreasing levels across the day. …”
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145456
Exploring the effects of COVID-19 on verbal memory function in schizophrenia: Multiple case study and brief literature review
Published 2024“…Left hippocampal volumes showed a comparatively slowed increase, while the right hippocampi decreased in volume, although these atrophy rates did not exceed those expected in general population samples. …”
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145457
Video_4_The Alternative Complement System Mediates Cell Death in Retinal Ischemia Reperfusion Injury.MOV
Published 2018“…Moreover, genetic deletion of complement component 3 (C3<sup>−/−</sup>) and complement factor b (Fb<sup>−/−</sup>) decreased IR-induced retinal apoptosis. Because vascular dysfunction is central to IR injury, we also assessed the role of complement in a model of shear stress. …”
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145458
Video_1_Comparison of the Mechanical Properties Between the Convex and Concave Inner/Apical Surfaces of the Developing Cerebrum.MOV
Published 2021“…Through indentation measurement using atomic force microscopy (AFM), we first found that Young’s modulus was higher at a concave-shaped apical surface of the pallium than at a convex-shaped apical surface of the ganglionic eminence (GE). …”
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145459
Table_1_Cultivar Contributes to the Beneficial Effects of Bacillus subtilis PTA-271 and Trichoderma atroviride SC1 to Protect Grapevine Against Neofusicoccum parvum.pdf
Published 2021“…Our findings highlight a common feature for both cultivars: salicylic acid (SA)-dependent defenses were strongly decreased in plants protected by the BCA, in contrast with symptomatic ones. …”
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145460
Identification of Virulence Properties in <i>Salmonella</i> Typhimurium DT104 Using <i>Caenorhabditis elegans</i>
Published 2013“…SNS12 exhibited decreased virulence in <i>C. elegans</i>, and we observed increased colonization and proliferation of the intestine of <i>C. elegans</i> by DT104. …”