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larger decrease » marked decrease (Expand Search)
large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
i large » ai large (Expand Search), _ large (Expand Search), a large (Expand Search)
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201
Large Hyperfine Coupling Arising from Pseudo‑<sup>2</sup>S Ground States in a Series of Lutetium(II) Metallocene Complexes
Published 2025“…Moreover, an extremely large splitting of the eight-line spectra indicates the presence of strong hyperfine coupling, and simulations provide isotropic hyperfine coupling constants of <i>A</i><sub>iso</sub> = 4.38, 4.30, and 4.17 GHz across the series, where the value of <i>A</i><sub>iso</sub> is found to decrease as the Cp–Lu–Cp angle becomes more acute. …”
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H‑NOX Influences Biofilm Formation, Central Metabolism, and Quorum Sensing in <i>Paracoccus denitrificans</i>
Published 2024“…In many species, the heme nitric oxide/oxygen binding proteins (H-NOX) play an important role in this process, although the signaling mechanisms and pathways in which they participate are quite diverse and largely unknown. In <i>Paracoccus denitrificans</i>, deletion of the <i>hnox</i> gene results in a severe biofilm-deficient phenotype. …”
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H‑NOX Influences Biofilm Formation, Central Metabolism, and Quorum Sensing in <i>Paracoccus denitrificans</i>
Published 2024“…In many species, the heme nitric oxide/oxygen binding proteins (H-NOX) play an important role in this process, although the signaling mechanisms and pathways in which they participate are quite diverse and largely unknown. In <i>Paracoccus denitrificans</i>, deletion of the <i>hnox</i> gene results in a severe biofilm-deficient phenotype. …”
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204
H‑NOX Influences Biofilm Formation, Central Metabolism, and Quorum Sensing in <i>Paracoccus denitrificans</i>
Published 2024“…In many species, the heme nitric oxide/oxygen binding proteins (H-NOX) play an important role in this process, although the signaling mechanisms and pathways in which they participate are quite diverse and largely unknown. In <i>Paracoccus denitrificans</i>, deletion of the <i>hnox</i> gene results in a severe biofilm-deficient phenotype. …”
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205
Data Sheet 1_Large scale atmospheric conditions favoring storm surges in the North and Baltic Seas and possible future changes.docx
Published 2025“…In contrast, a significant decrease of easterly effective winds is projected for all four locations at the Baltic Sea coast. …”
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206
Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma
Published 2025“…</p> <p><b>Abbreviation</b>: 3-MA, 3-methyladenine; AL, autolysosome; AP, autophagosome; Baf-A1, bafilomycin A<sub>1</sub>; BARA, β-α repeated autophagy specific domain; BH3, BCL2 homology 3 domain; CCD, coiled-coil domain; CHX, cycloheximide; Co-IP, co-immunoprecipitation; CQ, chloroquine; CTR, control; DAPI, 4′,6-diamidino-2-phenylindole; EBSS, Earle’s balanced salt solution; ECD, evolutionarily conserved domain; EEE, three-tyrosine phosphomimetic mutations Y229E Y233E Y352E; ER, endoplasmic reticulum; FFF, three-tyrosine non-phosphomimetic mutations; FFPE, formalin-fixed paraffin-embedded; FL, full-length; GIST, gastrointestinal stromal tumor; IB, immunoblotting; IHC, immunohistochemistry; KIT-HEK293, KIT stably expressing HEK293 cells; KRT20/CK20, keratin 20; LT, large T-antigen; LT339, MCPyV truncated LT antigen; LTco, codon-optimized MCPyV LT antigen; MCC, Merkel cell carcinoma; MCPyV<sup>−</sup>, MCPyV-negative; MCPyV, Merkel cell polyomavirus; MCPyV<sup>+</sup>, MCPyV-positive; PARP1, poly(ADP-ribose) polymerase 1; PCI, pan-caspase inhibitor; PI, propidium iodide; PtdIns3K, class III phosphatidylinositol 3-kinase; PtdIns3P, phosphatidylinositol-3-phosphate; RB1, RB transcriptional corepressor 1; RTKs, receptor tyrosine kinases; KITLG/SCF, KIT ligand; sT, small T-antigen; sTco, codon-optimized MCPyV sT antigen; T-B, Tat-BECN1; T-S, Tat-scrambled; TEM, transmission electron microscopy.…”
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207
Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx
Published 2025“…In addition, DLBCL cells exhibited increased expression of cholesterol uptake and synthesis proteins (CD36, SREBP2, and HMGCR) and decreased expression of efflux proteins (APOA1, NR1H2 and ABCG1), consistent with cholesterol metabolic reprogramming. …”
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Table1_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.docx
Published 2024“…Background<p>CDGSH iron-sulfur domain 2 (CISD2), an iron-sulfur protein with a [2Fe-2S] cluster, plays a pivotal role in the progression of various cancers, including Diffuse Large B-cell Lymphoma (DLBCL). …”
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210
Image1_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.JPEG
Published 2024“…Background<p>CDGSH iron-sulfur domain 2 (CISD2), an iron-sulfur protein with a [2Fe-2S] cluster, plays a pivotal role in the progression of various cancers, including Diffuse Large B-cell Lymphoma (DLBCL). …”
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Overview of the parameters used in the model.
Published 2024“…<div><p>Background</p><p>Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the <i>Aedes albopictus</i> mosquito and global climate change, pose a significant threat to public health. …”
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Mortality rates per lifecycle stage [28].
Published 2024“…<div><p>Background</p><p>Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the <i>Aedes albopictus</i> mosquito and global climate change, pose a significant threat to public health. …”
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