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marked decrease » marked increase (Expand Search)
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increase » increased (Expand Search)
marked decrease » marked increase (Expand Search)
large decrease » large increases (Expand Search), large degree (Expand Search)
ad greater » a greater (Expand Search), load greater (Expand Search), aged greater (Expand Search)
increase » increased (Expand Search)
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Withdrawal of Type I JAKinibs increased STAT phosphorylation, a phenomenon present but markedly lower in Type II JAKinibs.
Published 2025“…(A) pJAK2 peaked at time zero after exposure to baricitinib and ruxolitinib and then decreases. There was no increase in pJAK2 with CHZ868 treatment; (B) pSTAT1 proportion peaked after 60 minutes and was greater after Type I JAKinib withdrawal than Type II JAKinib withdrawal; <b>(C)</b> The pSTAT2 proportion peaked 60 minutes after Type I JAKinib withdrawal but this phenomenon was not seen with Type II JAKinib withdrawal.…”
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