DataSheet1_Metformin Combining PD-1 Inhibitor Enhanced Anti-Tumor Efficacy in STK11 Mutant Lung Cancer Through AXIN-1-Dependent Inhibition of STING Ubiquitination.PDF by Zhiguo Wang (219272)

“…</p><p>Results: Through colony formation assay, Ki67 incorporation assay, and CCK-8 assay, we found that metformin significantly enhanced the killing of H460 cells and A549 cells by T cells. In NOD-SCID xenografts, metformin in combination with PD-1 inhibitor pembrolizumab effectively decreased tumor growth and increased infiltration of CD8⁺ T cells. …”

Aerobic Exercise Inhibits Sympathetic Nerve Sprouting and Restores β-Adrenergic Receptor Balance in Rats with Myocardial Infarction by Ting Chen (15205)

“…<div><p>Background</p><p>Cardiac sympathetic nerve sprouting and the dysregulation of β-adrenergic receptor (β-AR) play a critical role in the deterioration of cardiac function after myocardial infarction (MI). …”

miR-93-5p knockdown repressed hepatocellular carcinoma progression via increasing ERBB4 and TETs-dependent DNA demethylation by Yuqiang Li (2016439)

“…TETs silence relieved the influence of miR-93-5p knockdown on cell proliferation and apoptosis. miR-93-5p knockdown decreased HCC growth in a xenograft model.</p> <p>miR-93-5p knockdown repressed the progression of HCC <i>via</i> increasing ERBB4 and TETs-dependent DNA demethylation.…”

Image_1_In ovo Feeding of L-Leucine Improves Antioxidative Capacity and Spleen Weight and Changes Amino Acid Concentrations in Broilers After Chronic Thermal Stress.JPEG by Guofeng Han (12259064)

“…Subsequent RNA-seq analysis in the spleen showed that a total of 77 significant differentially expressed genes (DEGs) were identified, including 62 upregulated DEGs and 15 downregulated DEGs. …”

Table_2_Xenobiotic Effects of Chlorine Dioxide to Escherichia coli O157:H7 on Non-host Tomato Environment Revealed by Transcriptional Network Modeling: Implications to Adaptation a... by Xiaomei Shu (6206294)

“…In contrast, more genes were further downregulated with exposure to 10 μg ClO₂ at the first hour, with the number of both upregulated and downregulated genes significantly decreasing at the second hour. A total of 810 genes were uniquely upregulated at the third hour at 10 μg ClO₂, suggesting that the potency of xenobiotic effects had led to potential adaptation. …”

Table_2_Tannic acid reduced apparent protein digestibility and induced oxidative stress and inflammatory response without altering growth performance and ruminal microbiota diversi... by Zuo Wang (8502849)

“…The increments of alanine aminotransferase (ALT), triglyceride (TG), cortisol (CORT), total antioxidant capacity (T-AOC), interleukin (IL)-1β, IL-6, and serumamyloid A (SAA), and decrements of globulin (GLB), immunoglobulin G (IgG), cholinesterase (CHE), glutathione reductase (GR), creatinine (CRE), growth hormone (GH), high-density lipoprotein cholesterol (HDLC), and insulin-like growth factor 1 (IGF-1) to different extents by TA addition were observed. …”

Image_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.jpg by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Table_3_Xenobiotic Effects of Chlorine Dioxide to Escherichia coli O157:H7 on Non-host Tomato Environment Revealed by Transcriptional Network Modeling: Implications to Adaptation a... by Xiaomei Shu (6206294)

“…In contrast, more genes were further downregulated with exposure to 10 μg ClO₂ at the first hour, with the number of both upregulated and downregulated genes significantly decreasing at the second hour. A total of 810 genes were uniquely upregulated at the third hour at 10 μg ClO₂, suggesting that the potency of xenobiotic effects had led to potential adaptation. …”

Biochemical data and western blot data. by Jun Ding (80820)

“…Herein, we evaluated whether LCZ696 attenuates renal fibrosis by inhibiting ASK1/JNK/p38 mitogen-activated protein kinase (MAPK)-mediated apoptosis in a rat model of unilateral ureteral obstruction (UUO) and in vitro. …”

Image 1_Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation.jpg by Hongyan Xu (29047)

“…</p>Methods<p>This study uses Quercus (oak) sawdust (OS) as a control to evaluate the potential of Korshinsk peashrub (KP), Hippophae rhamnoides (seabuckthorn) pruning (HRP), and Lycium barbarum (goji) pruning (LBP) in the cultivation of L. edodes by measuring parameters such as mycelium growth, yield, protein, fat, fiber, amino acids, soluble sugars, and organic acids. …”

Table_1_Safety and Immunological Evaluation of Interleukin-21 Plus Anti-α4β7 mAb Combination Therapy in Rhesus Macaques.docx by Maria Pino (109981)

“…<p>Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections compromise gut immunological barriers, inducing high levels of inflammation and a severe depletion of intestinal CD4⁺ T cells. …”

Quantification of abnormal QRS peaks predicts response to cardiac resynchronization therapy and tracks structural remodeling by Adrian M. Suszko (6577292)

“…For each precordial lead, QRSp was defined as the total number of peaks detected on the unfiltered QRS minus those detected on a smoothed moving average template QRS. CRT response was defined as >5% increase in left ventricular ejection fraction post-CRT.…”

Data_Sheet_1_The Ameliorating Effects of Bushen Huatan Granules and Kunling Wan on Polycystic Ovary Syndrome Induced by Dehydroepiandrosterone in Rats.docx by Yang Xu (178421)

“…</p>Conclusion<p>This study demonstrated BHG or KW as a potential strategy for treatment of PCOS induced by DHEA, and suggested that the beneficial role of the two medicines were mediated by different pathway with the effect of BHG being correlated with the regulation of mitochondria, while the effect of KW being attributable to protection of endoplasmic reticulum stress.…”

DataSheet_1_Association Between Nitric Oxide, Oxidative Stress, Eryptosis, Red Blood Cell Microparticles, and Vascular Function in Sickle Cell Anemia.docx by Elie Nader (3161037)

“…<p>Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO) bioavailability promote vasculopathy in sickle cell anemia (SCA). …”

Image_1_Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning.jpeg by Jing Wang (6206297)

“…Objective<p>The decreased stability of atherosclerotic plaques increases the risk of ischemic stroke. …”

Table 2_Modified maxillomandibular advancement for Eastern Asian patients with moderate or severe OSA: an anatomic and aerodynamic assessment of the upper airway.xlsx by Kan Li (490394)

“…</p>Conclusion<p>Modified MMA is an excellent therapeutic method for Eastern Asian patients with skeletal class Ⅱ dentomaxillofacial deformity suffering from moderate to severe OSA; it achieves a balance between esthetic improvement and therapeutic efficacy for OSA both anatomically and aerodynamically.…”

Table_5_Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning.xlsx by Jing Wang (6206297)

“…Objective<p>The decreased stability of atherosclerotic plaques increases the risk of ischemic stroke. …”

nPM exposure results in myelin injury and axonal damage in the corpus callosum. by Michelle Connor (5932034)

“…<p>(A) dMBP in the corpus callosum of mice exposed to filtered air and nPM. …”

Impact of Dietary Tomato Juice on Changes in Pulmonary Oxidative Stress, Inflammation and Structure Induced by Neonatal Hyperoxia in Mice (<i>Mus musculus</i>) by Sheena Bouch (3149889)

“…Our objective was to determine if dietary supplementation with a known source of antioxidants (tomato juice, TJ) could protect the developing lung from injury caused by breathing hyperoxic gas. …”

DataSheet_1_The duration and breadth of antibody responses to 3-dose of inactivated COVID-19 vaccinations in healthy blood donors: An observational study.docx by Shanhai Ou (9957037)

“…The nAbs of plasma samples (collected between 2-6 weeks after the 3^rd dose) from triple-vaccinated donors (n=94) showed a geometric mean titer of 145.3 (95% CI: 117.2 to 180.1) against the ancestral B.1, slightly reduced by 1.7-fold against Delta variant, but markedly decreased by 4-6 fold in neutralizing Omicron variants, including the sub-lineages of BA.1 (5.6-fold), BA.1.1 (6.0-fold), BA.2 (4.2-fold), B.2.12.1 (6.2-fold) and BA.4/5 (6.5-fold).…”