Table_1_Determination of the effective dose of dexmedetomidine to achieve loss of consciousness during anesthesia induction.DOCX by Bing Mu (163814)

“…Background<p>Dexmedetomidine (DEX) is a sedative with greater preservation of cognitive function, reduced respiratory depression, and improved patient arousability. …”

Image_2_Residual OXPHOS is required to drive primary and metastatic lung tumours in an orthotopic breast cancer model.tif by Patries Herst (18472197)

“…Background<p>Fast adaptation of glycolytic and mitochondrial energy pathways to changes in the tumour microenvironment is a hallmark of cancer. Purely glycolytic ρ⁰ tumour cells do not form primary tumours unless they acquire healthy mitochondria from their micro-environment. …”

Protein signatures in serum and urine in three murine urothelial cancer models. by Iliana K. Kerzeli (11090169)

“…Significantly altered serum proteins in (A) MB49 orthotopic model (n = 6), (B) Carcinogen induced female C57BL/6 mice (n = 6), (C) 10-week endpoint Hgf-Cdk4^R24C mice (n = 13), (D) MIBC endpoint Hgf-Cdk4^R24C mice (n = 8) compared to respective healthy controls (n = 6–10). …”

Image_2_ATF3 Suppresses Growth and Metastasis of Clear Cell Renal Cell Carcinoma by Deactivating EGFR/AKT/GSK3β/β-Catenin Signaling Pathway.TIFF by Shenglin Gao (10142900)

“…The potential mechanism affected by ATF3 was analyzed through gene set enrichment analysis (GSEA) and verified using western blotting, invasion assay, or immunofluorescence staining. Furthermore, a xenograft mouse model was used to assess the function of ATF3 in vivo.…”

Supplementary Material for: <b><i>NT5C2</i></b> Gene Polymorphisms and the Risk of Coronary Heart Disease by Chen X. (2888087)

“…<b><i>Background:</i></b> Increasing studies have reported that 5′-nucleotidase cytosolic II (<i>NT5C2</i>) has a strong relationship with coronary heart disease (CHD) development. …”

Image_1_The Interaction Mechanism Between Herpes Simplex Virus 1 Glycoprotein D and Host Antiviral Protein Viperin.jpg by Meili Li (286549)

“…<p>Viperin is an interferon-inducible protein that responsible for a variety of antiviral responses to different viruses. …”

Data_Sheet_1_Cytosolic Glucose-6-Phosphate Dehydrogenase Is Involved in Seed Germination and Root Growth Under Salinity in Arabidopsis.pdf by Lei Yang (102719)

“…Compared to wild type, the mutant seeds showed a reduced germination rate and root elongation under salt stress. …”

Data_Sheet_1_Peri-interventional Triple Therapy With Dabigatran Improves Vasomotion and Promotes Endothelialization in Porcine Coronary Stenting Model.docx by Rayyan Hemetsberger (5056196)

“…<p>Objective: We evaluated the short and long-term effect of peri-interventional dabigatran therapy on vasomotion, endothelialization, and neointimal formation in a porcine coronary artery stenting model.</p><p>Background: Stenting of coronary arteries induces local inflammation, impairs vasomotion and delays endothelialization.…”

XRD pattern of improved granite residual soil. by Ya Wang (1202)

“…In contrast, <i>Bacillus tequilensis</i> shows the highest improvement in cohesion, with a maximum increase of 316.19%. The solidification effect differed among different bacterial strains, with B. …”

Image_3_Hypoxia-Inducible Factor 1α and 2α Have Beneficial Effects in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Aged Rats.TIF by Xiangnan Du (8552319)

“…ACF also reversed the activation of the Akt signaling pathway induced by RIPC following stroke. HIF may play a key role in RIPC, which was likely mediated by the Akt signaling pathway and systemic modulation of the inflammatory response in aged rats.…”

Image_1_Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model.jpg by Bhornprom Yoysungnoen (17115046)

“…Male ICR mice were randomly divided into 3 groups: mice fed with a low-fat diet (LFD group); mice fed with very high fat diet (VHFD group), and mice fed with VHFD supplemented with THC (300 mg/kg/day orally) (VHFD+THC treated group) for 6 weeks. …”

Results of the D-H panel causality test. by Xiaoying Hu (2079796)

“…Conversely, renewable energy consumption (REC) is an element that can increase economic activity and therefore decline the environmental damages to secure a green economy. Likewise, the growth in cases of Covid-19 also reduces the usage of resources like land, water, and forests and subsequently decreases carbon emissions, promoting the green economy. …”

Image 3_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Neonatal ODA supplementation may offer a promising intervention to mitigate the cognitive deficits and brain changes induced by MSI during lactation.…”

Image_1_Metformin Ameliorates Gestational Diabetes Mellitus-Induced Endothelial Dysfunction via Downregulation of p65 and Upregulation of Nrf2.jpg by Cong Cong Sun (9501830)

“…<p>Gestational diabetes mellitus (GDM) causes oxidative stress in mothers and infants and causes vascular endothelial dysfunction, which is a key factor for maternal and fetal cardiovascular diseases in the later stage of GDM, seriously threatening the life and health of mothers and infants. …”

Image_2_Geographic Variation in the Petiole–Lamina Relationship of 325 Eastern Qinghai–Tibetan Woody Species: Analysis in Three Dimensions.pdf by Yanan Li (94033)

“…Understanding environmental gradients in the relationship and its underlying mechanisms remains a critical challenge for ecologists. We investigated the possible scaling of the petiole–lamina relationships in three dimensions, i.e., petiole length (PL) vs. lamina length (LL), petiole cross sectional area (PCA) vs. lamina area (LA), and petiole mass (PM) vs. lamina mass (LM), for 325 Qinghai–Tibetan woody species, and examined their relation to leaf form, altitude, climate, and vegetation types. …”

The TrkB was expressed in neurons in the injured brain and treatment with 7,8-dihydroxyflavone attenuated stretch-induced cytotoxicity and apoptosis in primary cultured neurons. by Chun-Hu Wu (306057)

“…<p><b>(A)</b> Cellular localization of phospho-TrkB is in the peri-contusion margin at 4 days post-TBI observed by immunofluorescence labeling. …”

Table2_Mid-Late Holocene Sub-Millennial Scale Inverse Trends of South Asian Summer and Winter Monsoons in Sri Lanka.docx by Kasun Gayantha (11834375)

“…Multiple proxies (diagnostic biomarkers, hydrogen and carbon isotopes of individual n-alkane, grain size, and Zr/Rb elemental ratio) indicate a sub-millennial scale decreasing trend of summer monsoon rainfall in the wet zone of Sri Lanka alongside an increasing trend of winter monsoon rainfall in the dry zone during the last ∼6000 years. …”

Changes in glycolysis, EMT markers, and ROS production after matrix detachment. by Minjong Lee (597002)

“…<p>(A) AR Huh-BAT cells had higher expression of HK II, p-PDH, rGCS, and MCT-1 compared to Huh-BAT and HepG2 cells at the indicated time points after matrix detachment. …”

Evaluation of relapse distance and osteoclast activity after retention following injection with anti-c-Fms antibody. by Jiawei Qi (6467441)

“…<p>(A) Scheme for the experiment. Mice were treated with experimental loading for 12 days, followed by resin retention for 4 weeks. …”

Image_3_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.tif by Dong-sheng Di (11634688)

“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”